Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip

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Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1039/B812987H
P698PubMed publication ID20023795
P5875ResearchGate publication ID40731285

P2093author name stringPaul C H Li
Xiaoyan Xue
XiuJun Li
P2860cites workRapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assaysQ25939005
Antiproliferative and apoptotic effects of chamomile extract in various human cancer cellsQ28253485
Regulation of cell death: the calcium-apoptosis linkQ29615554
Seven-transmembrane receptorsQ29619896
Chemical and physiological characterization of fluo-4 Ca(2+)-indicator dyesQ30855902
Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cellsQ31512518
Mitochondria and calcium: from cell signalling to cell deathQ34083618
Orphan G-protein-coupled receptors and natural ligand discoveryQ34175467
Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosisQ34275661
Glycyrrhizic acid inhibits virus growth and inactivates virus particlesQ34322209
G-protein-coupled receptors and cancer.Q34606002
Extracellular recordings of field potentials from single cardiomyocytesQ35021449
The endoplasmic reticulum: a multifunctional signaling organelleQ35051249
An Industrial Perspective on Utilizing Functional Ion Channel Assays for High Throughput ScreeningQ35105370
Mitochondria: a target for cancer therapyQ35545214
A kinetic model for calcium dynamics in RAW 264.7 cells: 1. Mechanisms, parameters, and subpopulational variabilityQ35878648
Techniques: high-throughput measurement of intracellular Ca(2+) -- back to basics.Q36088557
Micro total analysis systems. Latest advancements and trends.Q36505433
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune responseQ36584553
Analysis of single mammalian cells on-chipQ36772370
Calcium and cancer: targeting Ca2+ transportQ36856463
Same-single-cell analysis for the study of drug efflux modulation of multidrug resistant cells using a microfluidic chipQ39986874
Stimulation of single isolated adult ventricular myocytes within a low volume using a planar microelectrode arrayQ40252284
Evaluation of MTT assay for measurement of emodin-induced cytotoxicityQ40277867
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivoQ40416142
Isoliquiritigenin induces apoptosis and cell cycle arrest through p53-dependent pathway in Hep G2 cellsQ40426062
Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calciumQ40494431
Calcium ionophore, ionomycin inhibits growth of human bladder cancer cells both in vitro and in vivo with alteration of Bcl-2 and Bax expression levelsQ40933918
Activation of a Ca2+-permeable cation channel by two different inducers of apoptosis in a human prostatic cancer cell lineQ40957010
Study of the apoptosis induced in vitro by antitumoral drugs on leukaemic cellsQ41129539
Ionomycin activates electrogenic Ca2+ influx in rat thymic lymphocytesQ42076086
Apoptosis Induced by Isoliquiritigenin in Human Gastric Cancer MGC-803 CellsQ43814751
Parallel single-cell monitoring of receptor-triggered membrane translocation of a calcium-sensing protein moduleQ43909644
Taurine antagonizes the increase in intracellular calcium concentration induced by alpha-adrenergic stimulation in freshly isolated guinea-pig cardiomyocytesQ43999764
Isoliquiritigenin suppresses pulmonary metastasis of mouse renal cell carcinomaQ44017833
Microfluidic device for single-cell analysis.Q44023040
Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.Q44026925
Cell docking and on-chip monitoring of cellular reactions with a controlled concentration gradient on a microfluidic deviceQ44117098
Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cellsQ44317859
Isoliquiritigenin inhibits the growth of prostate cancerQ44410376
Localized chemical stimulation to micropatterned cells using multiple laminar fluid flows.Q44853752
Dynamic single-cell analysis for quantitative biology.Q45940878
Effect of methylglyoxal on intracellular calcium levels and viability in renal tubular cellsQ46373797
Microfluidic selection and retention of a single cardiac myocyte, on-chip dye loading, cell contraction by chemical stimulation, and quantitative fluorescent analysis of intracellular calciumQ46597919
Microfluidic device for electric field-driven single-cell capture and activationQ46779137
Real-time monitoring of intracellular calcium dynamic mobilization of a single cardiomyocyte in a microfluidic chip pertaining to drug discoveryQ46856168
Quantitative comparison between microfluidic and microtiter plate formats for cell-based assays.Q46871827
Effects of the licorice extract against tumor growth and cisplatin-induced toxicity in a mouse xenograft model of colon cancerQ46918053
Influence of hydrodynamic conditions on quantitative cellular assays in microfluidic systems.Q50949596
Microfluidic systems to examine intercellular coupling of pairs of cardiac myocytesQ50991765
Metabolic monitoring of the electrically stimulated single heart cell within a microfluidic platformQ51113229
A microfluidic-based system for analysis of single cells based on Ca2+ flux.Q51582945
A three-dimensional flow control concept for single-cell experiments on a microchip. 1. Cell selection, cell retention, cell culture, cell balancing, and cell scanningQ51595524
Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acidQ52571944
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
microfluidicsQ138845
cytotoxicityQ246181
P304page(s)90-98
P577publication date2008-11-12
P1433published inIntegrative BiologyQ1524032
P1476titleReal-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip
P478volume1

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cites work (P2860)
Q37552875A PDMS/paper/glass hybrid microfluidic biochip integrated with aptamer-functionalized graphene oxide nano-biosensors for one-step multiplexed pathogen detection
Q38439900A Review: The Pharmacology of Isoliquiritigenin
Q39590850A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells
Q34089110A versatile PDMS/paper hybrid microfluidic platform for sensitive infectious disease diagnosis
Q30370312Biomarker detection for disease diagnosis using cost-effective microfluidic platforms
Q91285944Dielectrophoretic trapping of single leukemic cells using the conventional and compact optical measurement systems
Q40661556High-Throughput Cytotoxicity Testing System of Acetaminophen Using a Microfluidic Device (MFD) in HepG2 Cells
Q36168144Low-cost bioanalysis on paper-based and its hybrid microfluidic platforms
Q37540653Microfluidic 3D cell culture: potential application for tissue-based bioassays
Q38789186Microfluidic technologies in cell isolation and analysis for biomedical applications
Q98649293Recent advances in microfluidic platforms for single-cell analysis in cancer biology, diagnosis and therapy
Q37741295Relationship between Porcine Sperm Motility and Sperm Enzymatic Activity using Paper-based Devices
Q37960084Strategies for the real-time detection of Ca2+ channel events of single cells: recent advances and new possibilities
Q37688692Study of flow behaviors on single-cell manipulation and shear stress reduction in microfluidic chips using computational fluid dynamics simulations

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