Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis

scientific article

Determining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

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P356DOI10.1002/BDRA.23511
P698PubMed publication ID27173682

P2093author name stringXin Yu
Lihua Wu
Li Wang
Zhen Wang
Ting Zhang
Xiaolin Lu
Shaofang Shangguan
Shaoyan Chang
P2860cites workEffects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductaseQ24555055
Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's roleQ26852086
Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: a systematic review and meta-analysis of trials and observational studiesQ28084461
Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin SupplementationQ29615365
Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defectsQ33531991
Breast cancer DNA methylation profiles are associated with tumor size and alcohol and folate intake.Q33649722
Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or =60 y in the United StatesQ33994343
A common mutation in the 5,10-methylenetetrahydrofolate reductase gene affects genomic DNA methylation through an interaction with folate status.Q34025724
A literature review of MTHFR (C677T and A1298C polymorphisms) and cancer riskQ34450001
Association between folate levels and CpG Island hypermethylation in normal colorectal mucosaQ34681062
Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanismsQ35190160
Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE reviewQ35672899
DNA methylation abnormalities in congenital heart diseaseQ36213648
Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer.Q36616379
The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasiaQ37318403
Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell linesQ37380412
The MTHFR C677T polymorphism and global DNA methylation in oral epithelial cellsQ37414862
One-carbon metabolism-genome interactions in folate-associated pathologiesQ37421241
Nutriepigenetic regulation by folate-homocysteine-methionine axis: a reviewQ38161417
Global DNA hypomethylation is associated with NTD-affected pregnancy: A case-control studyQ40353504
5,10-methylenetetrahydrofolate reductase (MTHFR) 677C-->T and 1298A-->C mutations are associated with DNA hypomethylationQ43073677
Influence of methylenetetrahydrofolate reductase polymorphisms in oral cancer patientsQ43495266
Folate levels and N(5),N(10)-methylenetetrahydrofolate reductase genotype (MTHFR) in mothers of offspring with neural tube defects: a case-control studyQ43664424
Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G polymorphisms influence on leukocyte genomic DNA methylation levelQ43806881
Metabolic effects of C677T and A1298C mutations at the MTHFR gene in Brazilian children with neural tube defectsQ43906630
Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population.Q44770564
The MTHFR 1298A>C polymorphism and genomic DNA methylation in human lymphocytes.Q46432965
P433issue8
P921main subjectDNA methylationQ874745
P304page(s)667-674
P577publication date2016-05-13
P1433published inBirth Defects Research Part A: Clinical and Molecular TeratologyQ15724446
P1476titleDetermining the association between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and genomic DNA methylation level: A meta-analysis
P478volume106

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cites work (P2860)
Q58771792Associations of the MTHFR rs1801133 polymorphism with coronary artery disease and lipid levels: a systematic review and updated meta-analysis
Q39336050Epigenetics, nutrition and mental health. Is there a relationship?
Q33552542Integrated approach of nutritional and molecular epidemiology, mineralogical and chemical pollutant characterisation: the protocol of a cross-sectional study in women
Q52689990No evidence for association of MTHFR 677C>T and 1298A>C variants with placental DNA methylation.
Q28074234Novel Approaches to Investigate One-Carbon Metabolism and Related B-Vitamins in Blood Pressure

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