Metronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use.

scientific article published on November 1978

Metronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1017119005
P356DOI10.2165/00003495-197816050-00002
P8608Fatcat IDrelease_umtr2undyfdybgponxheyxlpf4
P698PubMed publication ID363399

P50authorRex N. BrogdenQ62563651
P2093author name stringG S Avery
R C Heel
T M Speight
P2860cites workMetronidazole for Crohn's diseaseQ28317693
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Anaerobic infection in a neonate. Early detection by gas liquid chromatography and response to metronidazoleQ34985813
Antimicrobial susceptibilities of anaerobic bacteria: recent clinical isolatesQ35656719
Absence of Strand Breaks in Deoxyribonucleic Acid Treated with MetronidazoleQ36465236
Metronidazole versus anaerobes. In vitro data and initial clinical observationsQ36523211
A comparison of the in vitro activity of metronidazole, tinidazole, and nimorazole against Gram-negative anaerobic bacilliQ36593247
Comparison of two commercially available media for detection of bacteremiaQ37148874
Comparative Pharmacokinetic Studies of Ornidazole and Metronidazole in ManQ67438558
Metronidazole in prevention and treatment of bacteroides infections after appendicectomyQ67472039
Anaerobic bacteria in chronic otitis mediaQ67569380
Metronidazole in anaerobic infectionsQ67572526
Treatment with metronidazole of 48 patients with serious anaerobic infectionsQ67655856
Quantitative bacteriology of the vaginal floraQ67656917
Interaction of metronidazole with nucleic acids in vitroQ67660084
Pharmacokinetics of metronidazole during short-term therapy of trichomoniasis urogenitalisQ67705552
The stereoselective interaction of warfarin and metronidazole in manQ67745717
Anaerobic meningitis and bacteremia caused by Fusobacterium speciesQ67763377
Effect of tinidazole, metronidazole and nitrofurazone on nucleic acid synthesis in Clostridium bifermentansQ67789390
Metronidazole and anaerobic sepsisQ68230206
Activity of metronidazole against experimental tetanus and gas gangreneQ68587592
The mode of action of metronidazole in Trichomonas vaginalis and other micro-organismsQ68685745
The effect of metronidazole on the experimental mixed infection of oral anaerobesQ69013261
Carcinogenicity of 5-nitrofurans, 5-nitroimidazoles, 4-nitrobenzenes, and related compoundsQ69034594
The selective toxicity of antimicrobial nitroheterocyclic drugsQ69114674
Bacteriology and treatment of primary lung abscessQ69340935
The pharmacokinetics of metronidazole and tinidazole in manQ69462851
Bactericidal Activity of Five Antimicrobial Agents against Bacteroides fragilisQ70404015
Effect of metronidazole on hydrogen production by Clostridium acetobutylicumQ70434784
Induction of lung tumors and malignant lymphomas in mice by metronidazoleQ70448786
Anaerobic bacteremiaQ70483866
Anaerobic bacterial endocarditisQ71576432
The isolation and identification of the urinary oxidative metabolites of metronidazole in manQ72132852
Penetration of Cephalothin and Lincomycin into the Cerebrospinal FluidQ72337480
Disulfiram-metronidazoleQ72408021
The Peripheral White Blood Cells and MetronidazoleQ72742728
Bacteroides fragilis endocarditis, bacteremia and other infections treated with oral or intravenous metronidazoleQ45261698
Bacteriological study of otogenic cerebral abscesses: chemotherapeutic role of metronidazoleQ48257300
Bacteroides fragilis ventriculitis and meningitis. Report of two casesQ48373605
Letter: Treatment of a brain abscess due to Bacteroides fragilis with metronidazoleQ48400697
Treatment with metronidazole of three patients with serious infections due to Bacteroides fragilisQ48458260
Toxicity of Disulfiram Combined with MetronidazoleQ53774919
Blood levels of chemotherapeutic drugs and the pharmacokinetics of tinidazole and metronidazole.Q54130957
Anaerobic Bacterial Infections of the Female Genital TractQ54133629
Bacteroides fragilis resistant to metronidazole after long-term therapy.Q54588370
The bacteriology of aspiration pneumoniaQ54591610
Successful treatment of Bacteroides bacteraemia with metronidazole, after failure with clindamycin and lincomycin.Q54597640
Susceptibility of Anaerobic bacteria to carbenicillin, cefoxitin, and related drugs.Q54627673
Anaerobic septicemia from thrombophlebitis of the internal jugular vein. Successful treatment with metronidazole.Q54632935
Biochemical Characterization and in vitro Determination of Antibiotic Susceptibility of Clinical Isolates of Bacteroides fragilisQ54643598
Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgeryQ55339286
Letter: Metronidazole in treatment of empyemaQ55380503
Fusobacterium endocarditis treated with metronidazoleQ55692885
Mismanaged facial infectionQ66696114
Treatment of anaerobically infected pressure sores with topical metronidazoleQ66697539
Will the real Clostridium species responsible for antibiotic-associated colitis please step forward?Q66697788
Letter: Drug treatment in Crohn's diseaseQ66702815
Treatment of purulent anaerobic pleurisy by local injections of metronidazoleQ66847352
An evaluation of metronidazole in the prophylaxis and treatment of anaerobic infections in surgical patientsQ66904863
Bactericidal activity of metronidazole, tinidazole and ornidazole against Bacteroides fragilis in vitroQ67053531
Identification of Clostridium difficile as a cause of pseudomembranous colitisQ67288099
Bioassay of Metronidazole with Either Anaerobic or Aerobic IncubationQ67326056
Metronidazole treatment of liver abscess due to bacteroides fragilisQ67361357
Activity-electroreduction relationship of antimicrobial metronidazole analogsQ39192525
Prophylactic oral antimicrobial agents in elective colonic surgery. A controlled trialQ39355829
Bacteroides: an unusual cause of breast abscessQ39387983
Metronidazole and acneQ39393494
Prophylactic systemic antibiotics in colorectal surgeryQ39442335
What are Anaerobic Cocci?Q39458509
Inhibition of phagocytosis in vitro by obligate anaerobesQ39468353
The antimicrobial effect of combinations of clindamycin and metronidazole with spectinomycinnQ39754406
Assessment of the in vitro activity against Bacteroides spp. of spectinomycin, metronidazole and clindamycinQ39824858
Fixed Drug Eruption Due to MetronidazoleQ39831524
Susceptibility of Anaerobic Bacteria to Metronidazole: Relative Resistance of Non-Spore-Forming Gram-Positive BaccilliQ39921480
Infective endocarditis—1973Q39938233
Antibiotic Susceptibility Testing of Anaerobic Bacteria by the Standardized Disc Diffusion Method with Special Reference to Bacteroides fragilisQ39939580
Anaerobic infections: a reviewQ39940660
Antibiotic Susceptibility of Clostridium Species Isolated from Human InfectionsQ39954552
Metronidazole: view of uses and toxicityQ40062362
Antimicrobial activity of metronidazole in anaerobic bacteriaQ40301840
Susceptibility of Campylobacter fetus to twenty-two antimicrobial agentsQ40471086
Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methodsQ40617130
Use of High-Pressure Liquid Chromatography to Determine Plasma Levels of Metronidazole and Metabolites After Intravenous AdministrationQ40617971
Nonspecific vaginitis: role of Haemophilus vaginalis and treatment with metronidazoleQ40677662
The Anaerobic Culture of Clinical Specimens: A 14-Month StudyQ40751708
Metronidazole compared with penicillin in the treatment of acute dental infectionsQ40755013
Improving the performance of anaerobic bacteriology in a hospital laboratoryQ40757420
Bioavailability of metronidazole in fasting and non-fasting healthy subjects and in patients with Crohn's diseaseQ40809592
The effect of metronidazole on the incidence of postoperative wound infection in elective colon surgeryQ40855001
Protective effect of metronidazole in experimentalulcerative colitisQ40866948
Phase II study of metronidazole therapy for advanced colorectal carcinomaQ40887378
Pharmacokinetics and therapeutic efficacy of metronidazole at different dosagesQ40933462
Microbiological agar diffusion assay for metronidazole concentrations in serumQ40943242
Susceptibility of Clostridium ramosum to antimicrobial agentsQ40943384
Treatment of anaerobic infections with metronidazoleQ40944352
In vitro activity of josamycin and rosamicin against Bacteroides fragilis compared with clindamycin, erythromycin, and metronidazoleQ40946961
Susceptibility of anaerobic bacteria to 23 antimicrobial agentsQ40947577
Pharmacokinetics of metronidazole as determined by bioassayQ41031006
The Fate of Metronidazole and its Implications in ChemotherapyQ41070401
Metronidazole in the treatment of severe acute pericoronitis. A clinical trailQ41246178
Bactericidal activity of metronidazole against Bacteroides fragilisQ41261523
Prophylactic antibiotics in bowel surgeryQ42155736
The Use of Metronidazole in the Preparation of the Bowel for SurgeryQ42704454
Bacteriology of empyemaQ43461557
An investigation of interactions between metronidazole (“Flagyl”) and other antibacterial agentsQ43500428
The bioavailability of commercial metronidazole formulationsQ43512898
A study of carbon dioxide-dependent strains of Streptococcus milleriQ43747237
A significant interaction between metronidazole and warfarinQ43951690
Intra-abdominal abscessesQ43977746
The spectrum of antibacterial activity of metronidazoleQ43988870
Chemical reduction of the compulsion to drink with metronidazole: a new treatment modality in the therapeutic program of the alcoholic.Q44061532
Excretion of metroindazole in human bile. Investigations of hepatic bile, common duct bile, and gallbladder bileQ44155618
Bacteroides fragilis meningitisQ44293020
Activity of Combinations of Antimicrobial Agents against Bacteroides fragilisQ44296384
The action of metronidazole on DNAQ44570592
A new approach to patients with suspected anaerobic postpartum pelvic infections. Transabdominal uterine aspiration for culture and metronidazole for treatmentQ44774800
Letter: Value of metronidazole in septicemia caused by Bacteroides fragilis. 2 casesQ44931734
Metronidazole-spiramycin combination. In situ concentrations and synergism compared with the minimal inhibitory concentration of the buccal floraQ44959513
P433issue5
P921main subjectmetronidazoleQ169569
pharmacokineticsQ323936
P304page(s)387-417
P577publication date1978-11-01
P1433published inDrugsQ3040094
P1476titleMetronidazole in anaerobic infections: a review of its activity, pharmacokinetics and therapeutic use.
P478volume16

Reverse relations

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