Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines

scientific article published on December 1995

Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.39.12.2671
P8608Fatcat IDrelease_buhhzjuqhjepfgukyyzqxrhc3u
P932PMC publication ID163010
P698PubMed publication ID8593000

P2093author name stringJ A Williams
M T Makler
C K Angerhofer
J L Vennerstrom
P2860cites workNew colorimetric cytotoxicity assay for anticancer-drug screeningQ29615418
Inoculum effect with chloroquine and Plasmodium falciparumQ35535429
Mechanisms of methylene blue stimulation of the hexose monophosphate shunt in erythrocytesQ35904603
Antimalarials increase vesicle pH in Plasmodium falciparumQ36213878
Localization of mitochondria in living cells with rhodamine 123Q36356482
Potential antitumor phenoxazinesQ37766801
Glucose metabolism in the simian malaria parasitePlasmodium knowlesi: activities of the glycolytic and pentose phosphate pathways during the intraerythrocytic cycleQ39707275
Oxygen- and time-dependent effects of antibiotics and selected mitochondrial inhibitors on Plasmodium falciparum in cultureQ39833620
The effects of vital dyes on living organisms with special reference to methylene blue and neutral red.Q39866605
pH dependence of singlet oxygen production in aqueous solutions using toluidine blue as a photosensitizerQ40349656
Photochemical interactions of methylene blue and analogues with DNA and other biological substrates.Q40811273
Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquineQ41584415
Relevance of the chemical charge of rhodamine dyes to multiple drug resistanceQ41759369
Oxidant stress in malaria as probed by stable nitroxide radicals in erythrocytes infected with Plasmodium berghei. The effects of primaquine and chloroquineQ41912920
In vitro activity of mitochondrial ATP synthetase inhibitors against Plasmodium falciparumQ41935443
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivityQ41937582
The influence of methylene blue on the pentose phosphate pathway in erythrocytes of monkeys infected with Plasmodium knowlesiQ41939097
Hexose-monophosphate shunt activity in intact Plasmodium falciparum-infected erythrocytes and in free parasitesQ48006367
Measurement of the lactate dehydrogenase activity of Plasmodium falciparum as an assessment of parasitemiaQ48022469
Dyes, antipsychotic drugs, and antimicrobial activity. Fragments of a development, with special reference to the influence of Paul Ehrlich.Q49145255
Nile blue as a stain for exoerythrocytic forms of Plasmodium yoelii.Q50892483
Prevention of molecular self-association by sodium salicylate: effect on methylene blue.Q50910065
Pharmacokinetics of Highly Ionized Drugs III: Methylene Blue—Blood Levels in the Dog and Tissue Levels in the Rat following Intravenous AdministrationQ50967907
Pharmacokinetics of Highly Ionized Drugs II: Methylene Blue—Absorption, Metabolism, and Excretion in Man and Dog after Oral AdministrationQ50967916
Effects of mitochondrial inhibitors on intraerythrocytic Plasmodium falciparum in in vitro cultures.Q52262601
Solubility of organic solutes in ethanol/water mixtures.Q52363709
Plasmodium falciparum: cloning by single-erythrocyte micromanipulation and heterogeneity in vitroQ68136903
Membrane potential of Plasmodium falciparum gametocytes monitored with rhodamine 123Q68553046
Inhibition of in vitro growth of Plasmodium falciparum by a brief exposure to the cationic rhodamine dyesQ68926859
Vital staining of Plasmodium falciparum with cationic fluorescent rhodamine dyesQ69005656
Solvent systems for thin layer chromatography of biological dyesQ69397329
The mitochondrion of Plasmodium falciparum visualized by rhodamine 123 fluorescenceQ69909586
Cytotoxic and antimalarial bisbenzylisoquinoline alkaloids from Stephania erectaQ70601990
Supravital staining of mitochondria with phenosafranin dyesQ73324491
The chemotherapy of Plasmodium berghei. I. Resistance to drugsQ73342049
Public Health Weekly Reports for JUNE 5, 1925Q83539877
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)2671-2677
P577publication date1995-12-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleAntimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines
P478volume39

Reverse relations

cites work (P2860)
Q22061977A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine
Q47215265A Small Molecule Impedes Insulin Fibrillation: Another New Role of Phenothiazine Derivatives
Q59125579A Synthetic Approach to Pyrazolopyranopyrimidinones and Pyrazolopyranooxazinones as Antimicrobial Agents
Q30044470A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assay
Q41917197A non-radiolabelled ferriprotoporphyrin IX biomineralisation inhibition test for the high throughput screening of antimalarial compounds.
Q27972703Analysis of the vitamin B6 biosynthesis pathway in the human malaria parasite Plasmodium falciparum
Q36450015Analyzing Thiol-Dependent Redox Networks in the Presence of Methylene Blue and Other Antimalarial Agents with RT-PCR-Supported in silico Modeling
Q34456807Antimalarial compounds in Phase II clinical development.
Q46746230Antimalarial efficacy of methylene blue and menadione and their effect on glutathione metabolism of Plasmodium yoelii-infected albino mice
Q40050625Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes
Q56355670Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages
Q41909928Binding of phenazinium dye safranin T to polyriboadenylic acid: spectroscopic and thermodynamic study
Q26740407Bioactive Thiazine and Benzothiazine Derivatives: Green Synthesis Methods and Their Medicinal Importance
Q53215576Cyclodextrin induced controlled delivery of a biological photosensitizer from a nanocarrier to DNA.
Q37418342Cytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis
Q50449985DNA intercalation of methylene blue and quinacrine: new insights into base and sequence specificity from structural and thermodynamic studies with polynucleotides.
Q53696257Differential activity of methylene blue against erythrocytic and hepatic stages of Plasmodium.
Q33557946Discovery of Novel Benzo[a]phenoxazine SSJ-183 as a Drug Candidate for Malaria
Q36013371Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia
Q52565814Efficacy and safety of methylene blue in the treatment of malaria: a systematic review.
Q41926931Efficacy of eosin B as a new antimalarial drug in a murine model.
Q35023226Eosin B as a novel antimalarial agent for drug-resistant Plasmodium falciparum.
Q48047061Exploring the interaction of phenothiazinium dyes methylene blue, new methylene blue, azure A and azure B with tRNAPhe: spectroscopic, thermodynamic, voltammetric and molecular modeling approach.
Q42970993Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action
Q35813283Flavoprotein disulfide reductases: advances in chemistry and function
Q27641127Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development
Q34197581Glutathione – Functions and Metabolism in the Malarial Parasite Plasmodium falciparum
Q31119698Glycoluril-Derived Molecular Clips are Potent and Selective Receptors for Cationic Dyes in Water
Q36952772Haemozoin: from melatonin pigment to drug target, diagnostic tool, and immune modulator
Q33208055Healing of perforating rat corneal incisions closed with photodynamic laser-activated tissue glue.
Q34582501Hemozoin biocrystallization in Plasmodium falciparum and the antimalarial activity of crystallization inhibitors
Q40506281Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana).
Q41933403In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs
Q39610759In vitro assessment of methylene blue on chloroquine-sensitive and -resistant Plasmodium falciparum strains reveals synergistic action with artemisinins
Q24657634Interactions of methylene blue with human disulfide reductases and their orthologues from Plasmodium falciparum
Q34510543Kinetic characterization of glutathione reductase from the malarial parasite Plasmodium falciparum. Comparison with the human enzyme
Q91320732Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum
Q41119883Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs
Q35014719Methylene Blue--a therapeutic dye for all seasons?
Q34298547Methylene blue as an antimalarial agent
Q30851548Methylene blue based protein solder for vascular anastomoses: an in vitro burst pressure study
Q34105488Methylene blue derivatives--suitable photoantimicrobials for blood product disinfection?
Q34710568Methylene blue inhibits the asexual development of vivax malaria parasites from a region of increasing chloroquine resistance
Q41217736Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo
Q47590220Molecular binding of toxic phenothiazinium derivatives, azures to bovine serum albumin: A comparative spectroscopic, calorimetric, and in silico study
Q43249865Molecular recognition of cationic phenothiazinium and phenoxazinium dyes with pi-extended 2'-deoxyadenosine nucleotides
Q35581916New Antimalarial Drugs
Q41912987Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria
Q40364283Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties
Q37820273Photodynamic antimicrobial chemotherapy (PACT) for the treatment of malaria, leishmaniasis and trypanosomiasis
Q39180926Physicochemical properties and photodynamic activity of novel derivatives of triarylmethane and thiazine
Q35701564Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax
Q35124902Potentiation of the antimalarial agent rufigallol.
Q35571456Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue
Q33806128Reactions of antimalarial peroxides with each of leucomethylene blue and dihydroflavins: flavin reductase and the cofactor model exemplified
Q39014575Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue
Q41912859Safety of the combination of chloroquine and methylene blue in healthy adult men with G6PD deficiency from rural Burkina Faso
Q85106690Spectroscopic Characterization of the Interaction of Phenosafranin and Safranin O with Double Stranded, Heat Denatured and Single Stranded Calf Thymus DNA
Q74782581Studies of interaction between safranine T and double helix DNA by spectral methods
Q39833936Synthesis and antimalarial properties of streptocyanine dyes
Q43939884Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents
Q36051237The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites
Q36785808The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain
Q27672885The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue
Q41928320The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine
Q34424514The phenothiazinium chromophore and the evolution of antimalarial drugs
Q47443565The shape and size of hemozoin crystals distinguishes diverse Plasmodium species
Q35625144The use of dyes in modern biomedicine
Q35946446The use of fluorescence enhancement to improve the microscopic diagnosis of falciparum malaria
Q28469234Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target
Q38213893Toxicity of imine-iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects
Q41916522Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs
Q38176655Vital dyes in ophthalmology: a chemical perspective

Search more.