2,3-Diphosphoglycerate: Its Role in Health and Disease

scientific article published on January 1, 1979

2,3-Diphosphoglycerate: Its Role in Health and Disease is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3109/10408367909147131
P953full work available at URLhttp://www.tandfonline.com/doi/pdf/10.3109/10408367909147131
P698PubMed publication ID378537

P2093author name stringR. Juel
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X-ray Diffraction Study of Binding of 2,3-Diphosphoglycerate to Human DeoxyhaemoglobinQ28637081
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Polycythemia associated with a hemoglobinopathyQ34081848
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Hemoglobin Syracuse (alpha2beta2-143(H21)His leads to Pro), a new high-affinity variant detected by special electrophoretic methods. Observations on the auto-oxidation of normal and variant hemoglobinsQ34474836
Three-dimensional Fourier Synthesis of Horse Oxyhaemoglobin at 2.8 Å Resolution: The Atomic ModelQ34661824
Erythrocytosis associated with hemoglobin Rainier: oxygen equilibria and marrow regulationQ35571974
Effect of 2,3-diphosphoglycerate on oxygen affinity of blood in sickle cell anemiaQ35576771
The interaction of 2,3-diphosphoglycerate with various human hemoglobinsQ35577790
Physiologic effects of 2,3-DPG-depleted red cells with high affinity for oxygenQ70611143
Exchange transfusion in the newborn infant with fresh and “old” blood: The role of storage on 2,3-diphosphoglycerate, hemoglobin-oxygen affinity, and oxygen releaseQ70616272
Erythrocyte production and metabolism in anephric and uremic menQ70937195
Low Binding of 2,3-Diphosphoglycerate to Haemoglobin F: A Contribution to the Knowledge of the Binding Site and an Explanation for the High Oxygen Affinity of Foetal BloodQ71293796
Automatic procedure for the microestimation of 2,3-diphosphoglycerateQ71320990
An Enzymatic Assay of 2,3 - Diphosphoglycerate in BloodQ71328292
A mechanized system for the determination of ATP + ADP, 2,3-diphosphoglycerate, glucose 1,6-diphosphate and lactate in small amounts of blood cellsQ71432544
Red-Cell pH and Oxygen Affinity of HemoglobinQ71445102
Thyroid Hormone Control of Erythrocyte 2,3-Diphosphoglyceric Acid ConcentrationsQ71472523
Direct determination of 2,3-diphosphoglycerateQ71554077
Effect of normal metabolites on the oxygen-hemoglobin equilibriumQ71593314
Hemoglobin Function and 2,3-DPG Levels of Blood Stored at 4 C in ACD and CPD pH EffectQ71617489
Three-dimensional Fourier Synthesis of Human Deoxyhaemoglobin at 3.5 Å ResolutionQ71722196
The role of the left-shifted or right-shifted oxygen-hemoglobin equilibrium curveQ71747361
Affinity of Human Hemoglobin a to 2,3—Diphosphoglycerate. Effect of Hemoglobin Concentration and of pHQ71787336
Oxygen-linked hydrogen ion binding of human hemoglobin. Effects of carbon dioxide and 2,3-diphosphoglycerate. II. Studies on whole bloodQ71787342
Red Cell 2,3-Diphosphoglycerate and Adenosine Triphosphate in Patients with ShockQ71795292
Shift of the O2-Hb dissociation curve at altitude: mechanism and effectQ71831043
Adaptation to exercise: role of hemoglobin affinity for oxygen and 2,3-diphosphoglycerateQ71851373
Storage of Erythrocytes in Artificial MediaQ71854422
Complete Restoration of Oxygen Transport Function and 2,3-Diphosphoglycerate Concentration in Stored BloodQ71854442
Effect of organic phosphates on the oxygen equilibrium of carboxypeptidase digests of human hemoglobinQ72018726
Evidence for a Phosphorus-Depletion Syndrome in ManQ72019455
[Changes in the oxygen dissociation curves of the blood in hyperthyroidism and after administration of triiodothyronine in healthy persons and in rats]Q72152583
Restoration of Defective Oxygen-transport Function of Stored Red Blood Cells by Addition of InosineQ72185144
Effect of organic and inorganic phosphates on the oxygen equilibrium of human erythrocytesQ72243982
The Effect of the Addition of Adenine and Nucleosides at the Beginning of Storage on the Concentrations of Phosphates of Human Erythrocytes during Storage in Acid-Citrate-Dextrose and Citrate-Phosphate-DextroseQ72248039
Oxygen affinity of hemoglobin in patients with cardiovascular diseases, anemia, and cirrhosis of the liverQ72282464
Comparative viability of blood stored in ACD and CPDQ72344728
Effect of storage of blood in ACD-adenine-inorganic phosphate plus nucleosides on metabolic intermediates of human red cellsQ72349805
The Hemodynamic Response to Chronic AnemiaQ72371776
Red-Cell 2,3-Diphosphoglycerate Levels in Subjects with Chronic HypoxemiaQ72381751
Depletion and Regeneration of 2,3-diphosphoglyceric Acid in Stored Red Blood CellsQ72381965
Oxygen-hemoglobulin dissociation curves: effect of inherited enzyme defects of the red cellQ72411024
Effect of chronic hypoxic hypoxia on the O2-Hb dissociation curve and respiratory gas transport in manQ72472536
[Dependency of the synthesis of 2,3-diphosphoglycerate in human erythrocytes on the concentration of ADP]Q72499843
A clinical evaluation of the use of citrate-phosphate-dextrose solution in childrenQ72559405
Effect of inorganic and organic phosphates on formation of hemoglobin-phosphate complexes as determined by electrophoresisQ72629859
Studies on improved cell preservation. IV. Determinations of survival time and clinical experiences with IAG-preserved bloodQ72646226
pH and molecular CO2 components of the Bohr effect in human bloodQ72799019
Defective gas-transport function of stored red blood-cellsQ73364582
The influence of extracelluar factors involved in the collection of blood in ACD on maintenance of red cell viability during refrigerated storageQ74234729
Changes in oxygen-carrying function of human hemoglobin during storage in cold acid-citrate-dextrose solutionQ74279671
A cltrate-phosphatedextrose solution for the preservation of human bloodQ74803904
RED CELL PRESERVATION IN CITRATE-PHOSPHATE-DEXTROSE AND IN ACID-CITRATE-DEXTROSE: COMPARISON OF ERYTHROCYTE VIABILITY AFTER 28 DAYS REFRIGERATED STORAGEQ76600001
STUDY OF THE EFFECT OF UREMIC METABOLITES ON ERYTHROCYTE GLYCOLYSISQ76912519
ADENINE IN BLOOD PRESERVATION: POSTTRANSFUSION VIABILITY AND BIOCHEMICAL CHANGESQ76945203
FACTORS INFLUENCING THE ELECTROPHORETIC PATTERNS OF RED CELL HEMOLYZATES ANALYZED IN CACODYLATE BUFFERSQ76976663
EFFECT OF PH ON PRESERVATION OF RED CELL ATPQ77206916
Electrophoretic studies of red cell hemolysates supplemented with phosphorylated carbohydrate intermediatesQ79623540
TransfusionsQ82202500
Reduced Red Cell Glycolysis, 2,3-Diphosphoglycerate and Adenosine Triphosphate Concentration, and Increased Hemoglobin-Oxygen Affinity Caused by HypophosphatemiaQ93818717
Erythrocyte 2,3-Diphosphoglycerate in Adaptive Red-Cell-Volume DeficiencyQ93828471
Alterations of red-cell glycolytic intermediates and oxygen transport as a consequence of hypophosphatemia in patients receiving intravenous hyperalimentationQ93830641
pH dependency of 2,3-diphosphoglycerate content in red blood cellsQ114686671
Saturation dependency of the Bohr effect: interactions among H-+, CO2, and DPGQ116371084
Reciprocal binding of oxygen and diphosphoglycerate by human hemoglobinQ36467226
The relationship between red cell 2,3-diphosphoglycerate and levels of hemoglobin in the humanQ36475904
An improved automated method for the measurement of red cell 2,3-diphosphoglycerateQ36605396
The oxygen transport system of red blood cells during diabetic ketoacidosis and recoveryQ39067994
Oxygen Transport in Congenital Heart Disease: Influence of Fetal Hemoglobin, Red Cell pH, and 2,3-DiphosphoglycerateQ39094967
Dual effect of 2,3-diphosphoglycerate on the Bohr effects of human bloodQ39094978
A reassessment of the phosphoglycerate bypass enzymes in human erythrocytesQ39955938
Adenine and purine nucleosides in human red cell preservation: a reviewQ39966692
Viability and function of preserved red cellsQ39994926
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DIMENSIONAL, OSMOTIC, AND CHEMICAL CHANGES OF ERYTHROCYTES IN STORED BLOOD. I. BLOOD PRESERVED IN SODIUM CITRATE, NEUTRAL, AND ACID CITRATE-GLUCOSE (ACD) MIXTURESQ40997148
Mechanism of action of thyroid hormones on erythrocyte 2,3-diphosphoglyceric acid synthesisQ41710800
The oxygen dissociation curve in anemia of various typesQ42128342
The respiratory function of blood: transfusion and blood storage.Q43489106
Intraerythrocytic Adaptation to AnemiaQ43763418
2,3-Diphosphoglycerate fluctuations in erythrocytes reflecting pronounced blood glucose variation. In-vivo and in-vitro studies in normal, diabetic and hypoglycaemic subjectsQ43792087
Effects of salts and pH on the rate of erythrocyte diphosphoglycerate mutaseQ43880803
Effects of 2,3-diphosphoglycerate and other organic phosphate compounds on oxygen affinity and intracellular pH of human erythrocytesQ44036449
Depencency on acid-base status of blood of oxyhemoglobin dissociation and 2,3-diphosphoglycerate level in human erythrocytes. I. In vitro studies on reduced and oxygenated bloodQ44199534
Erythrocyte adenosine triphosphate depletion during hypophosphatemia in a uremic subjectQ44394497
Hb Helsinki: a variant with a high oxygen affinity and a substitution at a 2,3-DPG binding site (beta82[EF6] Lys replaced by Met).Q44790508
Preservation of red cell 2,3-diphosphoglycerate in modified ACD solution and in experimental artificial storage mediaQ44902721
Dependency on acid-base status of oxyhemoglobin dissociation and 2,3-diphosphoglycerate level in human erythrocytes. II. In vivo studiesQ44910975
The influence of aldosterone and cortisol on oxygen affinity and cation concentration of the bloodQ45048982
Reduction of the carbon dioxide affinity of human haemoglobin solutions by 2,3 diphosphoglycerateQ45050804
Comparison studies of whole blod stored in ACD and CPD and with adenineQ47817805
Oxygenation dependent variations of the Bohr coefficient related to whole blood and erythrocyte pH. Effect of lactic and carbonic acid.Q47825276
The binding of 2,3-diphosphoglycerate as a conformational probe of human hemoglobinsQ47974882
Does hemoglobin breathe, and if yes, how? The T and R state of hemoglobinQ47994816
Hyperphosphatemia, hypophosphatemia, and the oxy-hemoglobin dissociation curveQ48000210
Adaptation to anemia by decreased oxygen affinity of hemoglobin in patients on dialysisQ48028908
Oxygen-Linked Hydrogen Ion Binding of Human Hemoglobin. Effects of Carbon Dioxide and 2,3-DiphosphoglycerateQ52992247
Rejuvenation and Freezing of Outdated Stored Human Red CellsQ53752407
High Oxygen Affinity Variant of Haemoglobin Little Rock with Unique PropertiesQ53799020
The oxyhemoglobin dissociation curve in health and disease. Role of 2,3-diphosphoglycerate.Q54192768
2,3-Diphosphoglycerate and tissue oxygenation in uncontrolled diabetes mellitus.Q54195134
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Reduced Red Cell 2,3-Diphosphoglycerate and Adenosine Triphosphate, Hypophosphatemia, and Increased Hemoglobin-Oxygen Affinity after Cardiac SurgeryQ54766819
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Oxygen Binding by Haemoglobin J-Cape Town (α2 92 Arg → Gln)Q59023775
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Identification of Residues responsible for the Alkaline Bohr Effect in HaemoglobinQ59072005
Molecular Pathology of Human HaemoglobinQ59072058
A Direct Relationship between Adenosine Triphosphate-level and in vivo Viability of ErythrocytesQ59095387
Antagonistic influence of CO2 and 2,3 diphosphoglycerate on the Bohr effect of human haemoglobinQ64988922
Haemoglobin Rahere (beta Lys-Thr): A new high affinity haemoglobin associated with decreased 2, 3-diphosphoglycerate binding and relative polycythaemiaQ66684677
2,3-diphosphoglycerate levels in children with iron deficiency anemia and acute leukemiaQ66850466
Importance of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosisQ67270085
Blood storage XXV: Ascorbic acid (vitamin C) and dihydroxyacetone (DHA) maintenance of 2,3-DPG for six weeks in CPD-adenineQ67580799
Hemoglobin function in stored blood. XIX. Inosine maintenance of 2,3-DPG for 35 days in a CPD-adenine preservativeQ67688889
Adenine metabolism during and after exchange transfusions in newborn infants with CPD-adenine bloodQ67769724
Effect of plasma inorganic phosphate on tissue oxygenation during recovery from diabetic ketoacidosisQ68371429
Studies on erythrocyte glycolysis. 3. The effects of active cation transport, pH and inorganic phosphate concentration on erythrocyte glycolysisQ68382608
Kinetic properties of the phosphofructokinase from erythrocytes of rats and rabbits. I. The influence of potassium and ammonium ions and of inorganic phosphateQ68528962
Metabolism of 2,3-diphosphoglycerate and glycolysis in humna red blood cells under the infleucne of dipyridamole and inorganic sulfur compoundsQ68588644
A comparative study on the phosphoglyceric acid cycle in mammalian erythrocytesQ68591331
Purification and properties of 3-phosphoglyceric acid mutase from caprine erythrocytesQ68600762
A simple automates fluorometric method for the determination of 2,3-diphosphoglycerate in bloodQ68674403
Role of Penultimate Tyrosine in Haemoglobin β SubunitQ68991407
The role of 2,3-diphosphoglycerate in mediating hemoglobin function of mammalian red cellsQ69060715
Automated colorimetric determination of 2,3-diphosphoglycerateQ69383116
Preservation of red blood cell 2,3-diphosphoglycerate in stored blood containing dihydrozyacetoneQ69499522
The effect of ascorbate on the maintenance of 2,3-diphosphoglycerate (2,3-DPG) in stored red cellsQ69609063
The effect of ascorbate and dihydroxyacetone on the 2,3-diphosphoglycerate and ATP levels of stored human red cellsQ69783839
Bohr effect: interaction between H + , CO 2 , and 2,3-DPG in fresh and stored bloodQ70394756
Oxygen-linked hydrogen ion binding of human hemoglobin. Effects of carbon dioxide and 2,3-diphosphoglycerate. IV. Thermodynamical relationship between the variablesQ70403022
Androgen-Induced Increase in Red-Cell 2,3-DiphosphoglycerateQ70417966
Transfusion of Long Stored Whole Blood or Washed Red Blood Cells Incubated with Adenine and InosineQ70547177
On the mechanisms of the hypoxia-induced increase of 2,3-diphosphoglycerate in erythrocytes. Studies on rat erythrocytes in vivo and on human erythrocytes in vitroQ70565456
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)113-146
P577publication date1979-01-01
P1433published inCRC critical reviews in clinical laboratory sciencesQ27710552
P1476title2,3-Diphosphoglycerate: its role in health and disease
2,3-Diphosphoglycerate: Its Role in Health and Disease
P478volume10

Reverse relations

Q44469325The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patientscites workP2860

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