Knockdown of ubiquitin-conjugating enzyme E2C/UbcH10 expression by RNA interference inhibits glioma cell proliferation and enhances cell apoptosis in vitro

scientific article

Knockdown of ubiquitin-conjugating enzyme E2C/UbcH10 expression by RNA interference inhibits glioma cell proliferation and enhances cell apoptosis in vitro is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00432-009-0651-Z
P698PubMed publication ID19657671

P2093author name stringLei Jiang
Yi Bao
Guohan Hu
Xuehua Ding
Yicheng Lu
Chun Luo
Kehua Sun
Chengguang Huang
P2860cites workUbcH10 is the cancer-related E2 ubiquitin-conjugating enzyme.Q34215936
Checking out the G(2)/M transition.Q34282259
Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic originQ34328127
Restoration of p53 to limit tumor growthQ37016843
UbcH10 is overexpressed in malignant breast carcinomasQ40068570
Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivationQ41792415
UbcH10 expression may be a useful tool in the prognosis of ovarian carcinomasQ42599796
The processivity of multiubiquitination by the APC determines the order of substrate degradation.Q45345067
Expression of ubiquitin-conjugating enzyme E2C/UbcH10 in astrocytic tumorsQ45733871
Kinetochores and the checkpoint mechanism that monitors for defects in the chromosome segregation machineryQ77936231
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphaseQ24317284
UbcH10 overexpression may represent a marker of anaplastic thyroid carcinomasQ24651210
Expression and effect of inhibition of the ubiquitin-conjugating enzyme E2C on esophageal adenocarcinomaQ24681972
Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10Q27638680
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2Q27642888
An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivoQ28144965
How proteolysis drives the cell cycleQ28297983
Identification of overexpressed genes in hepatocellular carcinoma, with special reference to ubiquitin-conjugating enzyme E2C gene expressionQ33278046
Regulation of p53 downstream genes.Q33547816
The WHO classification of tumors of the nervous systemQ33845646
Regulation of the G2/M transition by p53.Q33943437
P433issue2
P921main subjectRNA interferenceQ201993
P304page(s)211-217
P577publication date2009-08-06
P1433published inJournal of Cancer Research and Clinical OncologyQ2081599
P1476titleKnockdown of ubiquitin-conjugating enzyme E2C/UbcH10 expression by RNA interference inhibits glioma cell proliferation and enhances cell apoptosis in vitro
P478volume136

Reverse relations

cites work (P2860)
Q36066046A monoclonal antibody against a potential cancer biomarker, human ubiquitin-conjugating enzyme E2
Q53204970A study of UbcH10 expression and its association with recurrence of meningiomas.
Q93048469Common Molecular Alterations in Canine Oligodendroglioma and Human Malignant Gliomas and Potential Novel Therapeutic Targets
Q41698570Forkhead Box M1 positively regulates UBE2C and protects glioma cells from autophagic death
Q34669229High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression
Q38857320Lentivirus-mediated RNA interference targeting UbcH10 reduces cell growth and invasion of human osteosarcoma cells via inhibition of Ki-67 and matrix metalloproteinases
Q37863285Processive ubiquitin chain formation by the anaphase-promoting complex.
Q42077314Spindle assembly checkpoint protein Cdc20 transcriptionally activates expression of ubiquitin carrier protein UbcH10
Q27332436Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown
Q37662326UBE2C is overexpressed in ESCC tissues and its abrogation attenuates the malignant phenotype of ESCC cell lines.
Q64935679UBE2C overexpression in melanoma and its essential role in G2/M transition.
Q50177240UBE2C promotes rectal carcinoma via miR-381.
Q90460960UbcH10 a Major Actor in Cancerogenesis and a Potential Tool for Diagnosis and Therapy
Q38881708UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients
Q39320437UbcH10 expression provides a useful tool for the prognosis and treatment of non-small cell lung cancer
Q31157579Ubiquitin-conjugating enzyme UBE2C is highly expressed in breast microcalcification lesions

Search more.