| scholarly article | Q13442814 |
| P356 | DOI | 10.1093/NAR/GKP593 |
| P953 | full work available at URL | https://academic.oup.com/nar/article-pdf/37/17/5678/4910074/gkp593.pdf |
| P932 | PMC publication ID | 2761266 |
| P698 | PubMed publication ID | 19625493 |
| P5875 | ResearchGate publication ID | 26688949 |
| P7228 | access restriction status | open access | Q232932 |
| P2093 | author name string | Hiroshi Nishida | |
| Naoto Tatewaki | |||
| Kam Ming Ko | |||
| Yuki Nakajima | |||
| Tetsuya Konishi | |||
| Yasuo Hamamori | |||
| Taku Magara | |||
| P2860 | cites work | A role for ATR in the DNA damage-induced phosphorylation of p53 | Q22008733 |
| Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9 | Q24297471 | ||
| MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation | Q24301197 | ||
| ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage | Q24306743 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage | Q24672492 | ||
| Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance | Q24672646 | ||
| ATM and ATR: networking cellular responses to DNA damage | Q28143424 | ||
| The many substrates and functions of ATM | Q28205055 | ||
| DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
| ATR and ATRIP: partners in checkpoint signaling | Q28207471 | ||
| The complexity of p53 modulation: emerging patterns from divergent signals | Q28284854 | ||
| p53 mutations in human cancers | Q28302973 | ||
| ATR disruption leads to chromosomal fragmentation and early embryonic lethality | Q28591433 | ||
| Cell cycle checkpoint signaling through the ATM and ATR kinases | Q29617837 | ||
| Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay. | Q34308225 | ||
| DNA damage induces phosphorylation of the amino terminus of p53 | Q35199554 | ||
| Targeting the checkpoint kinases: chemosensitization versus chemoprotection | Q35679781 | ||
| G2 checkpoint abrogators as anticancer drugs | Q35743997 | ||
| Profiling of UV-induced ATM/ATR signaling pathways. | Q36288898 | ||
| Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control | Q36490482 | ||
| The p53 tumour suppressor gene | Q37751892 | ||
| Doxorubicin activates ATM-dependent phosphorylation of multiple downstream targets in part through the generation of reactive oxygen species | Q38335343 | ||
| Schisandrin B enhances doxorubicin-induced apoptosis of cancer cells but not normal cells | Q40331763 | ||
| S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function | Q40769630 | ||
| Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents | Q40813162 | ||
| The Ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts | Q40814440 | ||
| Defective control of apoptosis and mitotic spindle checkpoint in heterozygous carriers of ATM mutations | Q40949253 | ||
| Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints | Q41063544 | ||
| How ATR turns on: TopBP1 goes on ATRIP with ATR. | Q42535886 | ||
| Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors. | Q44387424 | ||
| DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system | Q45025213 | ||
| Pharmacological actions and clinical use of fructus schizandrae | Q45212341 | ||
| Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity | Q47194705 | ||
| Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. | Q52536369 | ||
| Flow cytometry after bromodeoxyuridine labeling to measure S and G2+M phase durations plus doubling times in vitro and in vivo | Q80092973 | ||
| ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation | Q95721661 | ||
| P433 | issue | 17 | |
| P921 | main subject | Schisandra | Q1277423 |
| DNA damage | Q5205747 | ||
| Schizandrin B | Q72507130 | ||
| P6954 | online access status | open access | Q232932 |
| P304 | page(s) | 5678-5689 | |
| P577 | publication date | 2009-07-22 | |
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response | |
| P478 | volume | 37 |
| Q91640895 | A Comprehensive Review on Schisandrin B and Its Biological Properties |
| Q27320832 | A Naturally-Derived Compound Schisandrin B Enhanced Light Sensation in the pde6c Zebrafish Model of Retinal Degeneration |
| Q36908567 | A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations. |
| Q37316294 | A survey of chinese medicinal herbal treatment for chemotherapy-induced oral mucositis. |
| Q61660000 | ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells |
| Q47622968 | ATR/CHK1 inhibitors and cancer therapy |
| Q35561961 | Antiproliferative and apoptosis-inducing activity of schisandrin B against human glioma cells |
| Q28239738 | Chemical strategies for development of ATR inhibitors |
| Q88661083 | Clinically Applicable Inhibitors Impacting Genome Stability |
| Q39707460 | Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ. |
| Q26776513 | DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer |
| Q94474304 | DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer |
| Q38652528 | DNA replication stress and cancer: cause or cure? |
| Q41135683 | Development of pharmacodynamic biomarkers for ATR inhibitors. |
| Q38523589 | Drugging ATR: progress in the development of specific inhibitors for the treatment of cancer. |
| Q46990782 | Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: evidence for γH2A.X and DNA-PK-dependent pathway |
| Q42157376 | From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors. |
| Q34715440 | Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity |
| Q43890957 | In vitro antioxidation activity and genoprotective effect of selected Chinese medicinal herbs |
| Q37122690 | Inhibiting the DNA damage response as a therapeutic manoeuvre in cancer |
| Q39443786 | Inhibition of checkpoint kinase 1 abrogates G2/M checkpoint activation and promotes apoptosis under heat stress |
| Q39275968 | Manipulation of DNA damage checkpoint signaling in cancer cells by antioxidant biofactor (AOB). |
| Q37927146 | Mitochondrial decay in ageing: 'Qi-invigorating' schisandrin B as a hormetic agent for mitigating age-related diseases |
| Q46679237 | NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells |
| Q39362285 | Non-thermal DNA damage of cancer cells using near-infrared irradiation |
| Q39554874 | Persimmon leaf extract inhibits the ATM activity during DNA damage response induced by Doxorubicin in A549 lung adenocarcinoma cells |
| Q28066320 | Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer |
| Q38974279 | Prospects for the Use of ATR Inhibitors to Treat Cancer. |
| Q41475620 | Roles of DNA Damage Response Proteins in Mitogen-Induced Thp-1 Differentiation into Macrophage |
| Q27334832 | Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition |
| Q57150582 | Schisandrin B induces apoptosis and cell cycle arrest of gallbladder cancer cells |
| Q38753244 | Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells |
| Q28543891 | Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling |
| Q34099183 | Schisandrin B prevents doxorubicin-induced chronic cardiotoxicity and enhances its anticancer activity in vivo |
| Q35139388 | Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35. |
| Q41489534 | Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin |
| Q37976982 | Selective tumor killing based on specific DNA-damage response deficiencies |
| Q35908249 | Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase |
| Q89095370 | Targeting ATR in cancer |
| Q27023204 | Targeting DNA damage response in cancer therapy |
| Q39328356 | Targeting radiation-resistant hypoxic tumour cells through ATR inhibition |
| Q38817102 | Targeting the ATR-CHK1 Axis in Cancer Therapy |
| Q38868502 | The cell cycle checkpoint inhibitors in the treatment of leukemias. |
| Q84096090 | Ultrasound activates ataxia telangiectasia mutated- and rad3-related (ATR)-checkpoint kinase 1 (Chk1) pathway in human leukemia Jurkat cells |
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