Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23.

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Characterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID173286
P698PubMed publication ID7768599

P2093author name stringConlon PJ
Tsai CM
Hollingsworth RI
Parent JB
Gazzano-Santoro H
Kasler HG
Lill-Elghanian DA
P2860cites workCD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding proteinQ29615189
Structural characterization of the lipid A component of pathogenic Neisseria meningitidisQ31120578
Antibiotic proteins of human neutrophilsQ34262671
Crystal structure of an endotoxin-neutralizing protein from the horseshoe crab, Limulus anti-LPS factor, at 1.5 A resolution.Q34345762
Biochemistry of endotoxinsQ34564256
Human bactericidal/permeability-increasing protein and a recombinant NH2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteriaQ35822718
Resistance of gram-negative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structureQ37021236
Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapyQ37943123
Structural requirements of lipid A for endotoxicity and other biological activitiesQ38656773
Endotoxins and disease mechanismsQ39767274
Competition between rBPI23, a recombinant fragment of bactericidal/permeability-increasing protein, and lipopolysaccharide (LPS)-binding protein for binding to LPS and gram-negative bacteria.Q39859611
High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharideQ40152200
Recombinant human bactericidal/permeability-increasing protein (rBPI23) is a universal lipopolysaccharide-binding ligand.Q40375029
The role of bactericidal/permeability-increasing protein as a natural inhibitor of bacterial endotoxinQ40738309
Purification and characterization of a potent bactericidal and membrane active protein from the granules of human polymorphonuclear leukocytesQ40867899
Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils.Q41763332
27-Hydroxyoctacosanoic acid is a major structural fatty acyl component of the lipopolysaccharide of Rhizobium trifolii ANU 843.Q42197923
Protective effect of a recombinant amino-terminal fragment of bactericidal/permeability-increasing protein in experimental endotoxemiaQ43423537
Bactericidal/permeability-increasing protein has endotoxin-neutralizing activityQ43463435
Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein.Q43748246
A recombinant amino-terminal fragment of bactericidal/permeability increasing protein (rBPI23) inhibits soluble CD14-mediated lipopolysaccharide-induced endothelial adherence for human neutrophilsQ45250493
Separation and purification of a potent bactericidal/permeability-increasing protein and a closely associated phospholipase A2 from rabbit polymorphonuclear leukocytes. Observations on their relationshipQ45913463
Recombinant amino terminal fragment of bactericidal/permeability-increasing protein prevents hemodynamic responses to endotoxinQ46045448
Functional domains of recombinant bactericidal/permeability increasing protein (rBPI23).Q46200360
A recombinant amino terminal fragment of bactericidal/permeability-increasing protein inhibits the induction of leukocyte responses by LPS.Q46350804
A family of lipopolysaccharide binding proteins involved in responses to gram-negative sepsis.Q46536693
The role of lipopolysaccharides in the action of the bactericidal/permeability-increasing neutrophil protein on the bacterial envelopeQ50208372
The morphologic structure of isolated bacterial lipopolysaccharideQ50249563
A 25-kDa NH2-terminal fragment carries all the antibacterial activities of the human neutrophil 60-kDa bactericidal/permeability-increasing protein.Q54397174
Structure of lipid A component of Rhizobium leguminosarum bv. phaseoli lipopolysaccharide. Unique nonphosphorylated lipid A containing 2-amino-2-deoxygluconate, galacturonate, and glucosamine.Q54633255
Monocyte tissue factor induction by lipopolysaccharide (LPS): dependence on LPS-binding protein and CD14, and inhibition by a recombinant fragment of bactericidal/permeability-increasing protein.Q54635066
Protective effect of a recombinant fragment of bactericidal/permeability increasing protein against carbohydrate dyshomeostasis and tumor necrosis factor-alpha elevation in rat endotoxemia.Q54635114
Role of bactericidal permeability-increasing protein in the treatment of gram-negative pneumonia.Q54653696
Lipid A, the endotoxic center of bacterial lipopolysaccharides: relation of chemical structure to biological activityQ69038766
Preferential binding of the neutrophil cytoplasmic granule-derived bactericidal/permeability increasing protein to target bacteria. Implications and use as a means of purificationQ69338119
Isolation and characterization of the unusual lipopolysaccharide component, 2-amino-2-deoxy-2-N-(27-hydroxyoctacosanoyl)-3-O-(3-hydroxy- tetradecanoyl)-gluco-hexuronic acid, and its de-O-acylation product from the free lipid A of Rhizobium trifoliiQ69679785
Bactericidal/permeability-increasing protein inhibits induction of macrophage nitric oxide production by lipopolysaccharideQ72695808
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2201-2205
P577publication date1995-06-01
P1433published inInfection and ImmunityQ6029193
P1476titleCharacterization of the structural elements in lipid A required for binding of a recombinant fragment of bactericidal/permeability-increasing protein rBPI23.
P478volume63

Reverse relations

cites work (P2860)
Q30471677Annexins I and II bind to lipid A: a possible role in the inhibition of endotoxins
Q37869702Antimicrobial-sensing proteins in obesity and type 2 diabetes: the buffering efficiency hypothesis.
Q60307394Bactericidal/Permeability-Increasing Protein Is an Enhancer of Bacterial Lipoprotein Recognition
Q46002895Effect of bilayer phospholipid composition and curvature on ligand transfer by the alpha-tocopherol transfer protein.
Q33750066Lactoferrin inhibits the endotoxin interaction with CD14 by competition with the lipopolysaccharide-binding protein.
Q64069605Mechanistic research holds promise for bacterial vaccines and phage therapies for
Q35176262Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock
Q36205838Structural and functional features of a developmentally regulated lipopolysaccharide-binding protein
Q36902238The bactericidal/permeability-increasing protein (BPI) in infection and inflammatory disease.

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