WNT/beta-catenin increases the production of incretins by entero-endocrine cells.

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WNT/beta-catenin increases the production of incretins by entero-endocrine cells. is …
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scholarly articleQ13442814

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P356DOI10.1007/S00125-009-1429-1
P8608Fatcat IDrelease_z4xqas5akjdepfoivfu5nye4va
P698PubMed publication ID19582394
P5875ResearchGate publication ID26652155

P50authorJosé Manuel García-MartínezQ78725457
P2093author name stringC García-Jiménez
A Chocarro-Calvo
C M Moya
P2860cites workTCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3betaQ24311416
Brn-2 expression controls melanoma proliferation and is directly regulated by beta-cateninQ24317170
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinomaQ24336272
A molecular mechanism for the effect of lithium on developmentQ24629067
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Wnt/beta-catenin signaling in development and diseaseQ27860784
Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitorsQ28258745
Physiology of GIP--a lesson from GIP receptor knockout miceQ28302970
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout miceQ28510783
Chronic desensitization of the glucose-dependent insulinotropic polypeptide receptor in diabetic ratsQ28570330
Cell-specific expression of glucose-dependent-insulinotropic polypeptide is regulated by the transcription factor PDX-1Q28589086
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cellsQ29547557
Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditureQ30478488
DPP IV resistance and insulin releasing activity of a novel di-substituted analogue of glucose-dependent insulinotropic polypeptide, (Ser2-Asp13)GIP.Q30919420
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium.Q31855623
TCF transcription factors: molecular switches in carcinogenesisQ33755135
Gastric inhibitory polypeptide: the neglected incretin revisitedQ34758871
Wnt signaling: relevance to beta-cell biology and diabetesQ34858330
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomesQ35216433
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention ProgramQ35568877
Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetesQ35916172
Enteroendocrine precursors differentiate independently of Wnt and form serotonin expressing adenomas in response to active beta-cateninQ36090168
Lithium: potential therapeutics against acute brain injuries and chronic neurodegenerative diseasesQ36337317
Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signalingQ36513464
GATA-4 upregulates glucose-dependent insulinotropic polypeptide expression in cells of pancreatic and intestinal lineageQ37255197
Inhibition of gastric inhibitory polypeptide signaling prevents obesityQ38288099
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.Q38520593
Gastric inhibitory polypeptide: a gut hormone with anabolic functionsQ38666561
Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat dietQ39599495
Canonical Wnt signals are essential for homeostasis of the intestinal epitheliumQ39895829
Pax6 and Pdx1 are required for production of glucose-dependent insulinotropic polypeptide in proglucagon-expressing L cellsQ39966431
Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cellsQ40691546
Cell-specific Expression of the Glucose-dependent Insulinotropic Polypeptide Gene in a Mouse Neuroendocrine Tumor Cell LineQ41099776
Clinical studies with gastric inhibitory polypeptideQ41997201
Development of neuroendocrine tumors in the gastrointestinal tract of transgenic mice. Heterogeneity of hormone expressionQ42055042
Gastric Inhibitory Polypeptide (GIP) and Insulin Release in the Obese Zucker RatQ42455560
Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitusQ42496749
Beta-catenin can act as a nuclear import receptor for its partner transcription factor, lymphocyte enhancer factor-1 (lef-1).Q42813950
Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetesQ43778779
Using TESS to predict transcription factor binding sites in DNA sequenceQ44375395
Lithium inhibits function of voltage-dependent sodium channels and catecholamine secretion independent of glycogen synthase kinase-3 in adrenal chromaffin cells.Q46940106
Genetic inactivation of GIP signaling reverses aging-associated insulin resistance through body composition changesQ46949667
Weight change in the acute treatment of bipolar I disorder: a naturalistic observational study of psychiatric inpatientsQ47288578
Activation of the Wnt signaling pathway: a molecular mechanism for lithium actionQ48958687
The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.Q51465919
The glucose dependent insulinotropic polypeptide response to oral glucose and mixed meals is increased in patients with type 2 (non-insulin-dependent) diabetes mellitus.Q51619627
Glycogen Synthase Kinase-3 Modulates Neurite Outgrowth in Cultured Neurons: Possible Implications for Neurite Pathology in Alzheimer's DiseaseQ58415675
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat dietQ58448374
Comparison of the enteroinsular axis in two strains of obese rat, the fatty Zucker and the JCR:LA-corpulentQ67976335
WNT signalling is both an inducer and effector of glucagon-like peptide-1Q81716066
P433issue9
P304page(s)1913-1924
P577publication date2009-07-07
P1433published inDiabetologiaQ5270140
P1476titleWNT/beta-catenin increases the production of incretins by entero-endocrine cells
P478volume52

Reverse relations

cites work (P2860)
Q33811018Acute selective bioactivity of grape seed proanthocyanidins on enteroendocrine secretions in the gastrointestinal tract.
Q57402000Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Q37983846Diet: friend or foe of enteroendocrine cells--how it interacts with enteroendocrine cells
Q39168828GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin-induced diabetic mice and activates cAMP/PKA/β-catenin signaling in β-cells in vitro
Q37911549Glucose-dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity-associated disorders
Q26752511Inflammation Meets Metabolic Disease: Gut Feeling Mediated by GLP-1
Q36953864Interaction between diet and gastrointestinal endocrine cells
Q26823824New insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic β-cells: the involvement of the Wnt signaling pathway effector β-catenin
Q37763540The Incretins and Pancreatic beta-Cells: Use of Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Polypeptide to Cure Type 2 Diabetes Mellitus
Q27012497The alliance of mesenchymal stem cells, bone, and diabetes
Q90561539The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism
Q36058422The double trouble of metabolic diseases: the diabetes-cancer link
Q36309053The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective
Q36193707The role of the Wnt signaling pathway in incretin hormone production and function
Q37811421Wnt and Incretin Connections

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