Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression

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Dienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/MOLEHR/GAP042
P698PubMed publication ID19502247
P5875ResearchGate publication ID26272268

P2093author name stringTakashi Takeuchi
Satoru Kyo
Yutaka Shimizu
Masaki Inoue
Tohru Kiyono
Kiyoshi Mizuguchi
Shizuka Mita
P2860cites workComparison in gene expression of secretory human endometrium using laser microdissectionQ24796585
DienogestQ28289898
Analysis of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression in deep endometriosis and eutopic endometrium using laser capture microdissectionQ28305759
Identification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture modelQ28363408
DNA microarray analysis of gene expression profiles in deep endometriosis using laser capture microdissection.Q30766164
Hormonal pathology of the endometriumQ33886753
Progestins and progesterone in hormone replacement therapy and the risk of breast cancerQ34420425
Endometriosis: aetiology, pathogenesis and treatmentQ34427750
New progestagens for contraceptive use.Q34468158
New progestogens: a review of their effects in perimenopausal and postmenopausal womenQ34551983
Current place of progestins in the treatment of endometriosis-related complaintsQ34847482
Endometriosis: treatment strategiesQ35596254
Successful immortalization of endometrial glandular cells with normal structural and functional characteristicsQ35843291
Aromatase and other steroidogenic genes in endometriosis: translational aspectsQ36241031
Advances in the management of endometriosis: an update for cliniciansQ36310331
Progesterone resistance in endometriosis: link to failure to metabolize estradiolQ36365708
Inflammatory status influences aromatase and steroid receptor expression in endometriosis.Q36509755
The role of progestins in treating the pain of endometriosisQ36650353
Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis--a randomized, double-blind, multicenter, controlled trialQ39316616
Clinical response of abnormal endometrial growth to hormonal treatmentQ40642662
Regulation of functional steroid receptors and ligand-induced responses in telomerase-immortalized human endometrial epithelial cellsQ42476771
The inhibitory effect of dienogest, a synthetic steroid, on the growth of human endometrial stromal cells in vitroQ43560500
Cyclin D1 overexpression induces progestin resistance in T-47D breast cancer cells despite p27(Kip1) association with cyclin E-Cdk2.Q43759022
Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery: results of a prospective, multicenter, randomized studyQ43950321
A novel organotypic culture model for normal human endometrium: regulation of epithelial cell proliferation by estradiol and medroxyprogesterone acetateQ45234417
Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesisQ46200500
Progesterone and progestational compounds attenuate tumor necrosis factor alpha-induced interleukin-8 production via nuclear factor kappa B inactivation in endometriotic stromal cellsQ46468485
Reduced expression of progesterone receptor-B in the endometrium of women with endometriosis and in cocultures of endometrial cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxinQ46594488
The activation function-1 domain of estrogen receptor alpha in uterine stromal cells is required for mouse but not human uterine epithelial response to estrogen.Q46683753
High-dose pilot study with the novel progestogen dienogestin patients with endometriosisQ46979540
Human 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression and localization in term placenta and in endometrium during the menstrual cycle.Q50896417
P433issue10
P304page(s)693-701
P577publication date2009-06-05
P1433published inMolecular Human ReproductionQ15761794
P1476titleDienogest, a synthetic progestin, inhibits the proliferation of immortalized human endometrial epithelial cells with suppression of cyclin D1 gene expression
P478volume15

Reverse relations

cites work (P2860)
Q42090449Comparison of fertility-sparing treatments in patients with early endometrial cancer and atypical complex hyperplasia: A meta-analysis and systematic review
Q34343640Decorin induced by progesterone plays a crucial role in suppressing endometriosis
Q28296264Dienogest: a review of its use in the treatment of endometriosis
Q38663754Does dienogest influence the inflammatory response of endometriotic cells? A systematic review.
Q39258005Effects of dienogest on surgically induced endometriosis in rats after repeated oral administration
Q43061010Krüppel-like factor 4 mediates anti-proliferative effects of progesterone with G₀/G₁ arrest in human endometrial epithelial cells
Q35107985Lipoxin A₄ prevents the progression of de novo and established endometriosis in a mouse model by attenuating prostaglandin E₂ production and estrogen signaling
Q48059956Pelvic pain and quality of life of women with endometriosis during quadriphasic estradiol valerate/dienogest oral contraceptive: a patient-preference prospective 24-week pilot study
Q38471471Progestin effects in endometriosis treatment: new research on mechanisms
Q28083257Progestins in the fertility-sparing treatment and retreatment of patients with primary and recurrent endometrial cancer
Q52776100Short-term histopathological effects of dienogest therapy on ovarian endometriomas: in vivo, nonrandomized, controlled trial.
Q33778690The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis
Q37946399The role of prostaglandin E2 in endometriosis
Q50946182The use of an oral contraceptive containing estradiol valerate and dienogest before office operative hysteroscopy: a feasibility study.

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