Characterization of fhlA mutations resulting in ligand-independent transcriptional activation and ATP hydrolysis

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Characterization of fhlA mutations resulting in ligand-independent transcriptional activation and ATP hydrolysis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.179.1.41-45.1997
P932PMC publication ID178659
P698PubMed publication ID8981978

P2093author name stringA Böck
I Korsa
P2860cites workThe major dimerization determinants of the nitrogen regulatory protein NTRC from enteric bacteria lie in its carboxy-terminal domainQ72122417
Genetic evidence for activation of the positive transcriptional regulator Xy1R, a member of the NtrC family of regulators, by effector bindingQ72302905
DNA sequencing with chain-terminating inhibitorsQ22066207
The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependentQ24555682
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectorsQ26778475
Rapid and efficient site-specific mutagenesis without phenotypic selectionQ27860628
A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genesQ29547324
New approach to the cultivation of methanogenic bacteria: 2-mercaptoethanesulfonic acid (HS-CoM)-dependent growth of Methanobacterium ruminantium in a pressureized atmosphere.Q35228545
Phosphorylation of nitrogen regulator I of Escherichia coli induces strong cooperative binding to DNA essential for activation of transcriptionQ37043606
Effector-mediated stimulation of ATPase activity by the sigma 54-dependent transcriptional activator FHLA from Escherichia coliQ38295813
The nucleotide concentration determines the specificity of in vitro transcription activation by the sigma 54-dependent activator FhlA.Q39839743
Cloning and nucleotide sequence of the gene encoding the positive regulator (DmpR) of the phenol catabolic pathway encoded by pVI150 and identification of DmpR as a member of the NtrC family of transcriptional activatorsQ39925462
Sensing of aromatic compounds by the DmpR transcriptional activator of phenol-catabolizing Pseudomonas sp. strain CF600Q39930931
The central domain of Rhizobium leguminosarum DctD functions independently to activate transcriptionQ39936096
A common switch in activation of the response regulators NtrC and PhoB: phosphorylation induces dimerization of the receiver modulesQ40788975
Signal sensing by sigma 54-dependent regulators: derepression as a control mechanismQ41130496
Sequence and domain relationships of ntrC and nifA from Klebsiella pneumoniae: homologies to other regulatory proteins.Q42565883
Molecular characterization of an operon (hyp) necessary for the activity of the three hydrogenase isoenzymes inEscherichia coliQ42621838
Analysis of the hydA locus of Escherichia coli: two genes (hydN and hypF) involved in formate and hydrogen metabolismQ42631991
Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenlyase componentsQ42632998
The bacterial enhancer-binding protein NTRC is a molecular machine: ATP hydrolysis is coupled to transcriptional activationQ42681079
Mutational analysis of the operon (hyc) determining hydrogenase 3 formation in Escherichia coliQ43494980
Constitutive forms of the enhancer-binding protein NtrC: evidence that essential oligomerization determinants lie in the central activation domainQ44629082
Identification and sequence analysis of the gene encoding the transcriptional activator of the formate hydrogenlyase system of Escherichia coliQ45020757
Mutations in trans which affect the anaerobic expression of a formate dehydrogenase (fdhF) structural gene.Q45943043
Characterisation of a protease from Escherichia coli involved in hydrogenase maturationQ48075558
Characterization of divergent NtrA-dependent promoters in the anaerobically expressed gene cluster coding for hydrogenase 3 components of Escherichia coliQ48278846
Nucleotide sequence of the regulatory gene xylR of the TOL plasmid from Pseudomonas putidaQ48320573
Activation of the transcriptional regulator XylR of Pseudomonas putida by release of repression between functional domains.Q54615039
Regulated expression in vitro of genes coding for formate hydrogenlyase components of Escherichia coli.Q54630112
Purification and DNA-binding properties of FHLA, the transcriptional activator of the formate hydrogenlyase system from Escherichia coli.Q54630116
Characterization of a cis regulatory DNA element necessary for formate induction of the formate dehydrogenase gene (fdhF) of Escherichia coli.Q54734152
The seleno-polypeptide of formic dehydrogenase (formate hydrogen-lyase linked) from Escherichia coli: genetic analysis.Q54798285
In Vitro Activities of an N-terminal Truncated Form of XylR, a σ54-dependent Transcriptional Activator of Pseudomonas putidaQ57936271
Analysis of regulation of Klebsiella pneumoniae nitrogen fixation (nif) gene cluster with gene fusionsQ59070294
Mechanism of regulation of the formate-hydrogenlyase pathway by oxygen, nitrate, and pH: definition of the formate regulonQ67836270
Involvement of the ntrA gene product in the anaerobic metabolism of Escherichia coliQ68221710
Transformation of bacteria with plasmid DNA by electroporationQ70394587
Direct regulation of the ATPase activity of the transcriptional activator DmpR by aromatic compoundsQ70893897
P433issue1
P304page(s)41-45
P577publication date1997-01-01
P1433published inJournal of BacteriologyQ478419
P1476titleCharacterization of fhlA mutations resulting in ligand-independent transcriptional activation and ATP hydrolysis
P478volume179

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cites work (P2860)
Q48047346A small, stable RNA induced by oxidative stress: role as a pleiotropic regulator and antimutator
Q73883722Analysis of the domain structure and the DNA binding site of the transcriptional activator FhlA
Q24676977Cloning and characterization of two splice variants of human phosphodiesterase 11A
Q101574216Deacidification by FhlA-dependent hydrogenase is involved in urease activity and urinary stone formation in uropathogenic Proteus mirabilis
Q40387801Expression and regulation of a silent operon, hyf, coding for hydrogenase 4 isoenzyme in Escherichia coli
Q38629419Identification of the regulator gene responsible for the acetone-responsive expression of the binuclear iron monooxygenase gene cluster in mycobacteria
Q28593446Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A
Q22254649Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression
Q36393878Members of the IclR family of bacterial transcriptional regulators function as activators and/or repressors
Q24676441Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A
Q29346665Probing regulon of ArcA in Shewanella oneidensis MR-1 by integrated genomic analyses.
Q53943129Properties of a mutant form of the prokaryotic enhancer binding protein, NTRC, which hydrolyses ATP in the absence of effectors.
Q28751729Protein engineering of the transcriptional activator FhlA To enhance hydrogen production in Escherichia coli
Q37390901Receiver domains control the active-state stoichiometry of Aquifex aeolicus sigma54 activator NtrC4, as revealed by electrospray ionization mass spectrometry
Q39680672Regulation of the hydrogenase-4 operon of Escherichia coli by the sigma(54)-dependent transcriptional activators FhlA and HyfR.
Q34452640The GAF domain: an evolutionary link between diverse phototransducing proteins.
Q39394846The amino-terminal GAF domain of Azotobacter vinelandii NifA binds 2-oxoglutarate to resist inhibition by NifL under nitrogen-limiting conditions.

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