Profiling of the Compounds Absorbed in Human Plasma and Urine after Oral Administration of a Traditional Japanese (Kampo) Medicine, Daikenchuto

scientific article published on August 5, 2010

Profiling of the Compounds Absorbed in Human Plasma and Urine after Oral Administration of a Traditional Japanese (Kampo) Medicine, Daikenchuto is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1124/DMD.110.033589
P953full work available at URLhttp://intl-dmd.aspetjournals.org/cgi/content/abstract/38/11/2040
https://syndication.highwire.org/content/doi/10.1124/dmd.110.033589
P698PubMed publication ID20689019

P2093author name stringKazuhiro Hanazaki
Jun Iwabu
Junko Watanabe
Kazuhiro Hirakura
Yoshinori Ozaki
P2860cites workPungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channelsQ24622936
Pharmacokinetics of 6-gingerol, 8-gingerol, 10-gingerol, and 6-shogaol and conjugate metabolites in healthy human subjectsQ28291096
Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neuronsQ28588024
The herbal medicine Dai-kenchu-to and one of its active components [6]-shogaol increase intestinal blood flow in ratsQ30839923
Colonic vascular conductance increased by Daikenchuto via calcitonin gene-related peptide and receptor-activity modifying protein 1.Q33344656
Ginsenosides: are any of them candidates for drugs acting on the central nervous system?Q37031566
Compounds from Sichuan and Melegueta peppers activate, covalently and non-covalently, TRPA1 and TRPV1 channels.Q37395261
Current status of Kampo (Japanese herbal) medicines in Japanese clinical practice guidelinesQ37461679
Exodus of Kampo, traditional Japanese medicine, from the complementary and alternative medicines: is it time yet?Q37594963
A nonpungent component of steamed ginger--[10]-shogaol--increases adrenaline secretion via the activation of TRPV1.Q40193804
Effect of ginseng saponins on a rat visceral hypersensitivity modelQ40374699
5-HT3 receptor blocking activity of arylalkanes isolated from the rhizome of Zingiber officinale.Q40393714
Effect of daikenchuto (TU-100) on gastrointestinal and colonic transit in humansQ43105627
Ginsenoside Rb1 attenuates intestinal ischemia-reperfusion- induced liver injury by inhibiting NF-kappaB activation.Q43131668
Effect of Dai-kenchu-to on gastrointestinal motility based on differences in the site and timing of administrationQ43346117
Mechanisms for contractile effect of Dai-kenchu-to in isolated guinea pig ileumQ43561381
Intraduodenal and intrajejunal administration of the herbal medicine, dai-kenchu-tou, stimulates small intestinal motility via cholinergic receptors in conscious dogsQ43645933
Mechanism of atropine-resistant contraction induced by Dai-kenchu-to in guinea pig ileumQ43656553
Dai-kenchu-to enhances accelerated small intestinal movementQ43772074
Ginseng and ginsenoside Rg3, a newly identified active ingredient of ginseng, modulate Ca2+ channel currents in rat sensory neuronsQ43891467
Abatement of morphine-induced slowing in gastrointestinal transit by Dai-kenchu-to, a traditional Japanese herbal medicineQ43944068
Component of Zingiber officinale that improves the enhancement of small intestinal transportQ44187960
Components of Panax ginseng that improve accelerated small intestinal transitQ44260323
Self-micelle formation and the incorporation of lipid in the formulation affect the intestinal absorption of Panax notoginsengQ45826459
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Plasma pharmacokinetics and tissue distribution of [6]-gingerol in ratsQ46217897
Muscarinic, Ca(++) antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia.Q46351137
Evidence that TASK1 channels contribute to the background current in AH/type II neurons of the guinea-pig intestineQ46377830
6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophagesQ46443153
Pharmacokinetics of salvianolic acids after intravenous injection, with and without Panax quinquefolium protopanaxadiol saponins, in ratsQ46649445
The herbal medicine, Dai-Kenchu-to, accelerates delayed gastrointestinal transit after the operation in ratsQ46783474
The pharmacological effects of Daikenchuto, a traditional herbal medicine, on delayed gastrointestinal transit in rat postoperative ileusQ47765980
The preventive effect of Daikenchuto on postoperative adhesion-induced intestinal obstruction in ratsQ47792863
Construction of the Fingerprints of Ginseng Stem and Leaf Saponin Reference Substances and Spiked Plasma Sample by LC-ESI/MS and Its Application to Analyzing the Compounds Absorbed into Blood after Oral Administration of Ginseng Stem and Leaf SaponinQ57269471
Anti-emetic principles of Magnolia obovata bark and Zingiber officinale rhizomeQ72306923
Effect of Dai-kenchu-to on Obstructive Bowel Disease in ChildrenQ73337006
The effect of the herbal medicine dai-kenchu-to on post-operative ileusQ74797840
Effects of Dai-kenchu-to on intestinal obstruction following laparotomyQ78175082
Species differences in the prokinetic effects of gingerQ79928648
Effects of herbal medicine Dai-Kenchu-to on anorectal function in children with severe constipationQ80337909
Dietary herb extract dai-kenchu-to ameliorates constipation in parkinsonian patients (Parkinson's disease and multiple system atrophy)Q81139037
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectKampoQ403356
P304page(s)2040-2048
P577publication date2010-08-05
P1433published inDrug Metabolism and DispositionQ1261140
P1476titleProfiling of the compounds absorbed in human plasma and urine after oral administration of a traditional Japanese (kampo) medicine, daikenchuto
Profiling of the Compounds Absorbed in Human Plasma and Urine after Oral Administration of a Traditional Japanese (Kampo) Medicine, Daikenchuto
P478volume38

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