Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.

scientific article published on 27 March 2009

Diesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1165/RCMB.2008-0455OC
P698PubMed publication ID19329556

P2093author name stringDongsun Cao
James M Samet
Philip A Bromberg
P2860cites workRegulation of human lung epithelial cell numbers by diesel exhaust particles.Q46925801
Enhancement of allergic inflammation by the interaction between diesel exhaust particles and the immune systemQ46981373
Sp1 and Smad3 are required for high glucose-induced p21(WAF1) gene transcription in LLC-PK1 cellsQ50999305
Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis.Q51708828
STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiationQ57054852
Mdm2 Inhibits the Apoptotic Function of p53 Mainly by Targeting It for DegradationQ58431920
Quantitation of nitro- and dinitropolycyclic aromatic hydrocarbons in diesel exhaust particulate matterQ23923791
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanismQ24321756
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damageQ24530012
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial locationQ24648996
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollutionQ28205192
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1aQ28214385
Oxidants and signaling by mitogen-activated protein kinases in lung epitheliumQ28387471
Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1)Q28589090
Stats: transcriptional control and biological impactQ29547776
Stat3 as an oncogeneQ29614606
STATs in oncogenesisQ29617571
Synergistic effect of diesel organic extracts and allergen Der p 1 on the release of chemokines by peripheral blood mononuclear cells from allergic subjects: involvement of the map kinase pathwayQ31419211
The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stressQ34119808
Air pollution and cancer: biomarker studies in human populationsQ34445785
Free radical-induced damage to DNA: mechanisms and measurementQ34658029
Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylasesQ34835557
Sampling of vehicle emissions for chemical analysis and biological testingQ35037804
Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3.Q35207498
Oxidative Stress and Gene Transcription in Asthma and Chronic Obstructive Pulmonary Disease: Antioxidant Therapeutic TargetsQ35560623
Particulate air pollutants and asthma: a paradigm for the role of oxidative stress in PM-induced adverse health effectsQ35617299
Redox activation of p21Cip1/WAF1/Sdi1: a multifunctional regulator of cell survival and deathQ36009367
p21 stability: linking chaperones to a cell cycle checkpointQ36041416
Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cellsQ38334647
Opposite regulation of myc and p21waf1 transcription by STAT3 proteinsQ38360847
p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L).Q40252018
Nitrotyrosine-modified proteins and oxidative stress induced by diesel exhaust particles.Q40476267
DNA binding of polycyclic aromatic hydrocarbons in a human bronchial epithelial cell line treated with diesel and gasoline particulate extracts and benzo[a]pyreneQ40636679
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signalingQ40837817
Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis.Q40907792
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.Q41199732
Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epitheliumQ42434963
STAT3 is required for the gp130-mediated full activation of the c-myc geneQ42753357
Comparison of three different proliferation assays for mouse myoblast culturesQ43586781
P433issue1
P304page(s)88-95
P577publication date2009-03-27
P1433published inAmerican Journal of Respiratory Cell and Molecular BiologyQ4744268
P1476titleDiesel particle-induced transcriptional expression of p21 involves activation of EGFR, Src, and Stat3.
P478volume42

Reverse relations

cites work (P2860)
Q28386542Effects of controlled diesel exhaust exposure on apoptosis and proliferation markers in bronchial epithelium - an in vivo bronchoscopy study on asthmatics, rhinitics and healthy subjects
Q28395126Inflammation-related effects of diesel engine exhaust particles: studies on lung cells in vitro
Q39402899Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.
Q38742168MicroRNA-16-1 Inhibits Tumor Cell Proliferation and Induces Apoptosis in A549 Non-Small Cell Lung Carcinoma Cells
Q54503317Pollutant particles induce arginase II in human bronchial epithelial cells.
Q35659675Rapamycin Enhances the Anti-Cancer Effect of Dasatinib by Suppressing Src/PI3K/mTOR Pathway in NSCLC Cells
Q40974745Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion

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