scholarly article | Q13442814 |
P50 | author | Jonathan Javitch | Q47570044 |
Lei Shi | Q60659380 | ||
Harel Weinstein | Q62642462 | ||
Richard Neubig | Q67330747 | ||
P2093 | author name string | Aurelio Galli | |
Bipasha Guptaroy | |||
Margaret E Gnegy | |||
Minjia Zhang | |||
Erica Bowton | |||
Francesca Binda | |||
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N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux | Q24800348 | ||
VMD: visual molecular dynamics | Q27860554 | ||
Scalable molecular dynamics with NAMD | Q27860718 | ||
Comparative protein modelling by satisfaction of spatial restraints | Q27860866 | ||
Mechanisms of neurotransmitter release by amphetamines: a review | Q28256434 | ||
Regulation of amphetamine-stimulated dopamine efflux by protein kinase C beta | Q28573206 | ||
Phosphorylation of threonine residue 276 is required for acute regulation of serotonin transporter by cyclic GMP | Q28575143 | ||
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters | Q29616590 | ||
Molecular dynamics study of gating in the mechanosensitive channel of small conductance MscS | Q30476457 | ||
Generation of an activating Zn(2+) switch in the dopamine transporter: mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle | Q34010632 | ||
Structure and function of the dopamine transporter | Q34061069 | ||
The role of zinc ions in reverse transport mediated by monoamine transporters. | Q34122719 | ||
Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate | Q34166356 | ||
Probing a model of a GPCR/ligand complex in an explicit membrane environment: the human cholecystokinin-1 receptor. | Q34354083 | ||
Mechanism of chloride interaction with neurotransmitter:sodium symporters. | Q34664153 | ||
The top 20 dopamine transporter mutants: structure–function relationships and cocaine actions | Q35581491 | ||
A pincer-like configuration of TM2 in the human dopamine transporter is responsible for indirect effects on cocaine binding. | Q36282368 | ||
The dopamine transporter proteome | Q36458668 | ||
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding | Q37164373 | ||
The dopamine transporter carboxyl-terminal tail. Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain | Q38353878 | ||
Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites | Q38356253 | ||
The conserved glutamate (Glu136) in transmembrane domain 2 of the serotonin transporter is required for the conformational switch in the transport cycle. | Q40306798 | ||
Aspartate 345 of the dopamine transporter is critical for conformational changes in substrate translocation and cocaine binding | Q40609766 | ||
N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization. | Q40685824 | ||
Molecular characterization of the dopamine transporter. | Q40900564 | ||
Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. | Q41012269 | ||
Dopamine transporters are phosphorylated on N-terminal serines in rat striatum | Q42521018 | ||
Delineation of an endogenous zinc-binding site in the human dopamine transporter | Q42649758 | ||
The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site | Q42909481 | ||
Quantitative analysis of inward and outward transport rates in cells stably expressing the cloned human serotonin transporter: inconsistencies with the hypothesis of facilitated exchange diffusion | Q43578285 | ||
Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model | Q43901730 | ||
Amphetamine-induced dopamine efflux. A voltage-sensitive and intracellular Na+-dependent mechanism | Q44295653 | ||
Cocaine affinity decreased by mutations of aromatic residue phenylalanine 105 in the transmembrane domain 2 of dopamine transporter | Q44329259 | ||
Identification of intracellular residues in the dopamine transporter critical for regulation of transporter conformation and cocaine binding. | Q44642043 | ||
Phosphorylation and regulation of psychostimulant-sensitive neurotransmitter transporters | Q44830234 | ||
Effect of metabolic inhibitors and ouabain on amphetamine- and potassium-induced release of biogenic amines from isolated brain tissue | Q48211855 | ||
Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices. | Q48519912 | ||
Defining proximity relationships in the tertiary structure of the dopamine transporter. Identification of a conserved glutamic acid as a third coordinate in the endogenous Zn(2+)-binding site. | Q51427234 | ||
Multisubtrate mechanism for the inward transport of dopamine by the human dopamine transporter expressed in HEK cells and its inhibition by cocaine. | Q51449176 | ||
Differential effect of structural modification of human dopamine transporter on the inward and outward transport of dopamine | Q73472949 | ||
Amphetamine reverses or blocks the operation of the human noradrenaline transporter depending on its concentration: superfusion studies on transfected cells | Q77292449 | ||
A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function | Q80035224 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | dopamine | Q170304 |
P304 | page(s) | 514-524 | |
P577 | publication date | 2008-12-19 | |
P1433 | published in | Molecular Pharmacology | Q1943386 |
P1476 | title | A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation | |
P478 | volume | 75 |
Q37563730 | A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter. |
Q33742741 | An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter |
Q38917424 | An acute, epitope-specific modification in the dopamine transporter associated with methamphetamine-induced neurotoxicity. |
Q38811823 | Computational modeling of human dopamine transporter structures, mechanism and its interaction with HIV-1 transactivator of transcription. |
Q34668331 | Computational modeling of the N-terminus of the human dopamine transporter and its interaction with PIP2 -containing membranes. |
Q41106799 | Conformational Dynamics on the Extracellular Side of LeuT Controlled by Na+ and K+ Ions and the Protonation State of Glu290 |
Q33715513 | De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder |
Q38725778 | Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities |
Q37885392 | Dopamine release mediated by the dopamine transporter, facts and consequences |
Q47758420 | Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding |
Q36215945 | Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux |
Q33654916 | Dopamine transporter trafficking: rapid response on demand |
Q35850518 | Functional mechanisms of neurotransmitter transporters regulated by lipid-protein interactions of their terminal loops |
Q38812005 | HIV, Tat and dopamine transmission. |
Q36453517 | Importance of cholesterol in dopamine transporter function |
Q24598750 | Mechanisms of dopamine transporter regulation in normal and disease states |
Q92927264 | Molecular Mechanism and Dynamics of S-Deoxyephedrine Moving through Molecular Channels within D3R |
Q40415118 | Molecular Mechanism of Dopamine Transport by Human Dopamine Transporter |
Q35736694 | Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin |
Q36331487 | Monoamine transporter structure, function, dynamics, and drug discovery: a computational perspective. |
Q26777242 | Monoamine transporters: insights from molecular dynamics simulations |
Q34343025 | Mutation of tyrosine 470 of human dopamine transporter is critical for HIV-1 Tat-induced inhibition of dopamine transport and transporter conformational transitions. |
Q34597890 | Mutational analysis of the high-affinity zinc binding site validates a refined human dopamine transporter homology model |
Q64054571 | Mutational effects of human dopamine transporter at tyrosine88, lysine92, and histidine547 on basal and HIV-1 Tat-inhibited dopamine transport |
Q34458860 | Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport. |
Q41175275 | Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. |
Q34568367 | Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation |
Q36508575 | Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding |
Q47302876 | Quantitative Assessment of the Energetics of Dopamine Translocation by Human Dopamine Transporter |
Q43142319 | Reassessment of models of facilitated transport and cotransport |
Q34540543 | Regulation of monoamine transporters: Role of transporter phosphorylation |
Q34649517 | SLC6 transporters: structure, function, regulation, disease association and therapeutics |
Q34701009 | Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters |
Q27300323 | Spontaneous inward opening of the dopamine transporter is triggered by PIP2-regulated dynamics of the N-terminus |
Q36407799 | Steric hindrance mutagenesis in the conserved extracellular vestibule impedes allosteric binding of antidepressants to the serotonin transporter |
Q45329990 | Structure and Dynamics Study of LeuT Using the Markov State Model and Perturbation Response Scanning Reveals Distinct Ion Induced Conformational States |
Q33600236 | Substrate-dependent proton antiport in neurotransmitter:sodium symporters |
Q92857025 | Tales of tails in transporters |
Q38721916 | Tamoxifen and its active metabolites inhibit dopamine transporter function independently of the estrogen receptors |
Q33796294 | The N terminus of monoamine transporters is a lever required for the action of amphetamines |
Q36990361 | The binding sites for benztropines and dopamine in the dopamine transporter overlap. |
Q52649972 | The dopamine transporter: An unrecognized nexus for dysfunctional peripheral immunity and signaling in Parkinson's Disease. |
Q41922188 | The role of human dopamine transporter in NeuroAIDS. |
Q33813126 | The substrate-driven transition to an inward-facing conformation in the functional mechanism of the dopamine transporter |
Q35647386 | Tyrosine phosphorylation of the human serotonin transporter: a role in the transporter stability and function |
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