Impaired Regulation of Tumor Suppressor p53 Caused by Mutations in the Xeroderma Pigmentosum DDB2 Gene: Mutual Regulatory Interactions between p48DDB2 and p53

scientific article published on November 1, 2003

Impaired Regulation of Tumor Suppressor p53 Caused by Mutations in the Xeroderma Pigmentosum DDB2 Gene: Mutual Regulatory Interactions between p48DDB2 and p53 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.23.21.7540-7553.2003
P953full work available at URLhttps://europepmc.org/articles/PMC207631
https://europepmc.org/articles/pmc207631?pdf=render
https://europepmc.org/articles/PMC207631?pdf=render
https://doi.org/10.1128/mcb.23.21.7540-7553.2003
https://journals.asm.org/doi/pdf/10.1128/MCB.23.21.7540-7553.2003
https://www.tandfonline.com/doi/pdf/10.1128/MCB.23.21.7540-7553.2003
P932PMC publication ID207631
P698PubMed publication ID14560002

P2093author name stringToshiki Itoh
Stuart Linn
Cristin O'Shea
P2860cites workThe Hallmarks of CancerQ221226
Transcriptional activation of the MUC2 gene by p53.Q40698245
Profile of gene expression regulated by induced p53: connection to the TGF-beta familyQ40893077
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Reconstitution of human DNA repair excision nuclease in a highly defined systemQ41370395
Human damage-specific DNA-binding protein p48. Characterization of XPE mutations and regulation following UV irradiation.Q41731658
A novel form of Epstein-Barr virus latency in normal B cells in vivoQ45789413
Abnormal regulation of DDB2 gene expression in xeroderma pigmentosum group E strainsQ46631171
Reinvestigation of the classification of five cell strains of xeroderma pigmentosum group E with reclassification of three of them.Q53438317
p14ARF links the tumour suppressors RB and p53.Q55067966
Relative frequency and morphology of cancers in carriers of germline TP53 mutationsQ57266809
U.v.-induced nuclear accumulation of p53 is evoked through DNA damage of actively transcribed genes independent of the cell cycleQ72185052
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathQ24312211
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinasesQ24319848
Mdm2 promotes the rapid degradation of p53Q24322597
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53Q24328775
p53 Binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice.Q24537298
Regulation of p53 stability by Mdm2Q27860744
WAF1, a potential mediator of p53 tumor suppressionQ27861121
Surfing the p53 networkQ28032484
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damageQ28138556
Proliferation, cell cycle and apoptosis in cancerQ28189476
Death and anti-death: tumour resistance to apoptosisQ28217065
Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding proteinQ28271155
Tumor suppressor p53 is a direct transcriptional activator of the human bax geneQ28306186
UV damage, DNA repair and skin carcinogenesisQ29394071
TRANSFAC: transcriptional regulation, from patterns to profilesQ29547394
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Life-or-death decisions by the Bcl-2 protein family.Q31879227
Having it both ways: transcription factors that bind DNA and RNA.Q33337762
p53 binds selectively to the 5' untranslated region of cdk4, an RNA element necessary and sufficient for transforming growth factor beta- and p53-mediated translational inhibition of cdk4.Q33605464
The p53 pathwayQ33643359
Regulation of the p53 tumor suppressor proteinQ33792315
Regulation of p53 stabilityQ33807793
Regulation of p53 in response to DNA damageQ33807801
Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigenQ33913536
UV-induced DNA damage, repair, mutations and oncogenic pathways in skin cancerQ33955751
The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcriptionQ33958642
The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cellsQ34012408
The role of p53 and pRB in apoptosis and cancerQ34493147
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repairQ34810919
Segregation analysis of cancer in families of childhood soft-tissue-sarcoma patientsQ35195645
Mammalian DNA nucleotide excision repair reconstituted with purified protein components.Q36697936
A newly identified patient with clinical xeroderma pigmentosum phenotype has a non-sense mutation in the DDB2 gene and incomplete repair in (6-4) photoproducts.Q38321077
A transcriptionally active DNA-binding site for human p53 protein complexesQ40655196
P4510describes a project that usesImageQuantQ112270642
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
regulation of gene expressionQ411391
tumor suppressor geneQ422445
xeroderma pigmentosumQ612693
P304page(s)7540-7553
P577publication date2003-11-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleImpaired Regulation of Tumor Suppressor p53 Caused by Mutations in the Xeroderma Pigmentosum DDB2 Gene: Mutual Regulatory Interactions between p48DDB2 and p53
P478volume23

Reverse relations

cites work (P2860)
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