PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens

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PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/MC.20476
P932PMC publication ID3113613
P698PubMed publication ID18756441
P5875ResearchGate publication ID23222800

P2093author name stringMarcelo G Kazanietz
Liqing Xiao
Anatilde Gonzalez-Guerrico
P2860cites workRegulation of expression and activity of four PKC isozymes in confluent and mechanically stimulated UMR-108 osteoblastic cellsQ44884059
Effects of sequential treatments with chemotherapeutic drugs followed by TRAIL on prostate cancer in vitro and in vivoQ45076479
Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdeltaQ45250873
12-O-tetradecanoylphorbol-13-acetate-induced apoptosis in LNCaP cells is mediated through ceramide synthase.Q48029879
Targeting the protein kinase C family: are we there yet?Q52579980
Synergistic interactions between 12-0-tetradecanoylphorbol-13-acetate (TPA) and imatinib in patients with chronic myeloid leukemia in blastic phase that is resistant to standard-dose imatinib.Q53335365
Reversal of radiation resistance in LNCaP cells by targeting apoptosis through ceramide synthase.Q54073998
Persistent membrane translocation of protein kinase C alpha during 12-0-tetradecanoylphorbol-13-acetate-induced apoptosis of LNCaP human prostate cancer cellsQ73115578
Regulation of PKC delta expression by estrogen and rat placental lactogen-1 in luteinized rat ovarian granulosa cellsQ73897840
Regulation of TNF mediated antiapoptotic signaling in human neutrophils: role of delta-PKC and ERK1/2Q79397275
PKCdelta mediates anti-proliferative, pro-apoptic effects of testosterone on coronary smooth muscleQ80346339
Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression modelQ24795055
Regulation of cell apoptosis by protein kinase c deltaQ28201453
Protein kinase Cepsilon interacts with Bax and promotes survival of human prostate cancer cellsQ28206601
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesQ29614338
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathwayQ33253015
Serine/threonine protein kinases and apoptosis.Q33876765
Protein kinase Cdelta amplifies ceramide formation via mitochondrial signaling in prostate cancer cellsQ34789995
Death receptor-induced cell death in prostate cancerQ35613236
Down-regulation of ATM protein sensitizes human prostate cancer cells to radiation-induced apoptosisQ35758289
Protein kinase C and prostate carcinogenesis: targeting the cell cycle and apoptotic mechanismsQ35816725
Pathways of apoptotic and non-apoptotic death in tumour cellsQ35852309
Identification of novel androgen receptor target genes in prostate cancerQ35865261
Protein kinase Cepsilon makes the life and death decisionQ36002759
Overview of cell death signaling pathwaysQ36051647
Targeting death receptors in bladder, prostate and renal cancerQ36366078
Elucidating the role of protein kinase C in chronic lymphocytic leukaemiaQ36535850
Protein kinase C and other diacylglycerol effectors in cancerQ36769838
Protein kinase Cdelta and apoptosisQ36979517
Androgens regulate protein kinase Cdelta transcription and modulate its apoptotic function in prostate cancer cellsQ38306396
JNK interacting protein 1 (JIP-1) protects LNCaP prostate cancer cells from growth arrest and apoptosis mediated by 12-0-tetradecanoylphorbol-13-acetate (TPA).Q38795160
Signaling pathways for germ cell death in adult cynomolgus monkeys (Macaca fascicularis) induced by mild testicular hyperthermia and exogenous testosterone treatmentQ40231310
Effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) in combination with paclitaxel (Taxol) on prostate Cancer LNCaP cells cultured in vitro or grown as xenograft tumors in immunodeficient miceQ40272626
Phorbol ester-induced apoptosis in prostate cancer cells via autocrine activation of the extrinsic apoptotic cascade: a key role for protein kinase C deltaQ40369101
Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanismsQ40529766
Regulation of protein kinase C delta by estrogen in the MCF-7 human breast cancer cell lineQ40957799
Overexpression of PKCepsilon in R6 fibroblasts causes increased production of active TGFbetaQ41046065
Retinoblastoma protein-dependent growth signal conflict and caspase activity are required for protein kinase C-signaled apoptosis of prostate epithelial cellsQ41091784
1,25-Dihydroxyvitamin D3 stimulates expression and translocation of protein kinase Calpha and Cdelta via a nongenomic mechanism and rapidly induces phosphorylation of a 33-kDa protein in acute promyelocytic NB4 cellsQ41186113
Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic miceQ42451410
BAG-1 expression in hyperplastic and neoplastic prostate tissue: is there any relationship with BCL-related proteins and androgen receptor status?Q42490394
PKC, p42/44 MAPK and p38 MAPK regulate hepatocyte growth factor secretion from human astrocytoma cells.Q42525071
PKC delta mediates ionizing radiation-induced activation of c-Jun NH(2)-terminal kinase through MKK7 in human thyroid cellsQ43583425
Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathwayQ44489751
Drug interactions between the proteasome inhibitor bortezomib and cytotoxic chemotherapy, tumor necrosis factor (TNF) alpha, and TNF-related apoptosis-inducing ligand in prostate cancer.Q44615067
P433issue3
P921main subjectprostate cancerQ181257
P304page(s)187-195
P577publication date2009-03-01
P1433published inMolecular CarcinogenesisQ15724597
P1476titlePKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens
P478volume48

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cites work (P2860)
Q36674584A Signaling Network Controlling Androgenic Repression of c-Fos Protein in Prostate Adenocarcinoma Cells
Q35144545A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activities
Q54111064Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer.
Q35007641Daphnoretin-induced apoptosis in HeLa cells: a possible mitochondria-dependent pathway
Q39199813Differential signaling of the GnRH receptor in pituitary gonadotrope cell lines and prostate cancer cell lines
Q57107409Inflammation and NF-κB Signaling in Prostate Cancer: Mechanisms and Clinical Implications
Q38633660KLF5 promotes apoptosis induced by phorbol ester as an effector of the autocrine factor TNFα in LNCaP prostate cancer cells.
Q36530805PKCδ activation mediates angiogenesis via NADPH oxidase activity in PC-3 prostate cancer cells
Q47399023Prostate-specific membrane antigen cleavage of vitamin B9 stimulates oncogenic signaling through metabotropic glutamate receptors.
Q59072618Protein Kinase C (PKC) Isozymes and Cancer
Q38171231Protein kinase C and cancer: what we know and what we do not.
Q37447640ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK.
Q34796929Regulation of Transcriptional Networks by PKC Isozymes: Identification of c-Rel as a Key Transcription Factor for PKC-Regulated Genes
Q34074278Regulation of prostate cancer cell survival by protein kinase Cepsilon involves bad phosphorylation and modulation of the TNFalpha/JNK pathway
Q34949801The synthetic bryostatin analog Merle 23 dissects distinct mechanisms of bryostatin activity in the LNCaP human prostate cancer cell line

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