Is reducing variability of blood glucose the real but hidden target of intensive insulin therapy?

scientific article

Is reducing variability of blood glucose the real but hidden target of intensive insulin therapy? is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1007342318
P356DOI10.1186/CC7755
P932PMC publication ID2689479
P698PubMed publication ID19435472
P5875ResearchGate publication ID24420914

P50authorRinaldo BellomoQ28321777
P2093author name stringMichael C Reade
Moritoki Egi
P2860cites workRepetitive fluctuations in blood glucose enhance monocyte adhesion to the endothelium of rat thoracic aortaQ48436420
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.Q51500191
Circadian rhythm of blood glucose values in critically ill patients.Q53846806
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Mean Amplitude of Glycemic Excursions, a Measure of Diabetic InstabilityQ71568252
Randomized trial of insulin-glucose infusion followed by subcutaneous insulin treatment in diabetic patients with acute myocardial infarction (DIGAMI study): effects on mortality at 1 yearQ72351090
Glucose fluctuation on the progression of diabetic macroangiopathy--new findings from monocyte adhesion to endothelial cellsQ80225813
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Intensive insulin therapy in critically ill patientsQ29618795
Benefits and risks of tight glucose control in critically ill adults: a meta-analysisQ33363493
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shockQ34314380
Intensive insulin therapy in the medical ICU.Q34490623
Glucose variability and mortality in patients with sepsis.Q35222489
Insulin resistance and hyperglycemia in critical illness: role of insulin in glycemic controlQ35651338
Perioperative diabetic and hyperglycemic management issuesQ35738424
Prospective randomised study of intensive insulin treatment on long term survival after acute myocardial infarction in patients with diabetes mellitus. DIGAMI (Diabetes Mellitus, Insulin Glucose Infusion in Acute Myocardial Infarction) Study GroupQ36244558
Continuous glucose monitoring in patients with type 2 diabetes: Why? When? Whom?Q36744408
The impact of the severity of sepsis on the risk of hypoglycaemia and glycaemic variabilityQ36993184
Glycemic variability: a strong independent predictor of mortality in critically ill patientsQ37282216
Variability of blood glucose concentration and short-term mortality in critically ill patientsQ40303337
Intermittent high glucose enhances apoptosis in human umbilical vein endothelial cells in cultureQ43762927
Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic controlQ44308911
Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activationQ44631833
Glycemic variability and its responses to intensive insulin treatment in newly diagnosed type 2 diabetes.Q46275290
Blood glucose variability is associated with mortality in the surgical intensive care unitQ46427807
Alterations in glucose homeostasis in the pediatric intensive care unit: Hyperglycemia and glucose variability are associated with increased mortality and morbidityQ46582052
Glycemic control in the intensive care unit: why we should wait for NICE-SUGAR.Q46846318
Glucose fluctuations and activation of oxidative stress in patients with type 1 diabetes.Q46906803
P433issue2
P921main subjectglycobiologyQ899224
preproinsulinQ7240673
P304page(s)302
P577publication date2009-04-06
P1433published inCritical CareQ5186602
P1476titleIs reducing variability of blood glucose the real but hidden target of intensive insulin therapy?
P478volume13

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cites work (P2860)
Q91768301Association of multiple glycemic parameters at intensive care unit admission with mortality and clinical outcomes in critically ill patients
Q34807345Characteristics and effects of nurse dosing over-rides on computer-based intensive insulin therapy protocol performance
Q37765323Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trials
Q33821884Coefficient of glucose variation is independently associated with mortality in critically ill patients receiving intravenous insulin
Q35952655Continuous Glucose Monitoring in Patients Undergoing Extracorporeal Ventricular Assist Therapy
Q37867298Current and future treatment considerations in the management of aneurysmal subarachnoid hemorrhage
Q37833518Glucose variability measures and their effect on mortality: a systematic review
Q98771370Glycemic Variability: An Independent Predictor of Mortality and the Impact of Age in Pediatric Intensive Care Unit
Q37640683Glycemic control in critically ill patients.
Q46275849Impact of real-time continuous glucose monitoring on glucose variability in critically ill patients
Q37789585Intensive insulin therapy during cardiovascular surgery
Q24282606Limitations of medical research and evidence at the patient-clinician encounter scale
Q37867296Management of spontaneous nontraumatic intracranial hemorrhage
Q39974347NICE-SUGAR: the end of a sweet dream?
Q34153353The use of exenatide in severely burned pediatric patients

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