Overview of protein expression by mammalian cells

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Overview of protein expression by mammalian cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/0471140864.PS0509S10
P698PubMed publication ID18429190
P5875ResearchGate publication ID5424078

P2093author name stringD Gray
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Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activityQ24612623
Tyrosine sulfation is a trans-Golgi-specific protein modificationQ24680180
Folding and assembly of viral membrane proteinsQ27865318
Mechanisms of intracellular protein transportQ28131681
Assembly of asparagine-linked oligosaccharidesQ28131690
Post-translational chemical modification(s) of proteinsQ28244774
Lysosomal enzyme targeting. N-Acetylglucosaminylphosphotransferase selectively phosphorylates native lysosomal enzymesQ28268788
Expression, purification, and characterization of recombinant gamma-carboxylated factor IX synthesized in Chinese hamster ovary cellsQ28303798
Vitamin K-dependent carboxylaseQ28306468
Protein folding in the cellQ29547792
Patterns of amino acids near signal-sequence cleavage sitesQ29616542
Molecular dissection of the secretory pathwayQ29618201
A C-terminal signal prevents secretion of luminal ER proteinsQ29618994
Oxidized redox state of glutathione in the endoplasmic reticulumQ29619789
Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulumQ29620019
Electron probe microanalysis of calcium release and magnesium uptake by endoplasmic reticulum in bee photoreceptorsQ30454157
Foreign gene expression (beta-galactosidase) during the cell cycle phases in recombinant CHO cellsQ33350310
N-glycans of recombinant human interferon-gamma change during batch culture of chinese hamster ovary cells.Q33351396
Cell cycle analysis of foreign gene (beta-galactosidase) expression in recombinant mouse cells under control of mouse mammary tumor virus promoterQ33351694
Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenaseQ33830825
A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase geneQ33928279
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinantsQ34055183
Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutantQ34196337
Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA geneQ34253873
Calnexin: a membrane-bound chaperone of the endoplasmic reticulumQ34342505
Firefly luciferase is targeted to peroxisomes in mammalian cellsQ34623298
Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptorQ34826693
Nutrient optimization for high density biological production applicationsQ35288133
The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein propertiesQ35292620
S phase-specific synthesis of dihydrofolate reductase in Chinese hamster ovary cellsQ35462864
Selection and amplification of heterologous genes encoding adenosine deaminase in mammalian cellsQ35604068
A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi regionQ36217608
Membrane integration and intracellular transport of the coronavirus glycoprotein E1, a class III membrane glycoproteinQ69838758
Dialyzable serum components can support the growth of hybridoma cell lines in vitroQ71553184
Monosaccharide and oligosaccharide analysis of isoelectric focusing-separated and blotted granulocyte colony-stimulating factor glycoforms using high-pH anion-exchange chromatography with pulsed amperometric detectionQ71669353
Replacement of transferrin by simple iron compounds for MDCK cells grown and subcultured in serum-free mediumQ71722233
The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrixQ72405724
Intracellular folding of tissue-type plasminogen activator. Effects of disulfide bond formation on N-linked glycosylation and secretionQ72591976
A new vector for the high level expression of chimeric antibodies in myeloma cellsQ72773574
Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cellsQ72956707
Nutrition needs of mammalian cells in tissue cultureQ73806241
CO(2) in large-scale and high-density CHO cell perfusion cultureQ83497563
Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartmentQ36531845
Isolation and expression of an altered mouse dihydrofolate reductase cDNA.Q36614733
Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneityQ36765148
Amplification and expression of heterologous ornithine decarboxylase in Chinese hamster cellsQ36783327
Glycosylation and biological activity of CAMPATH-1H expressed in different cell lines and grown under different culture conditionsQ36809014
Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein and the role of posttranslational modifications in its binding functionQ36846952
Golgi retention of a trans-Golgi membrane protein, galactosyltransferase, requires cysteine and histidine residues within the membrane-anchoring domainQ37002762
The fats of life: the importance and function of protein acylationQ38003899
Molecular chaperones: proteins essential for the biogenesis of some macromolecular structuresQ38365596
Proteolytic processing and physiological regulationQ38685151
Protein oligomerization in the endoplasmic reticulumQ38737584
Mechanism of protein translocation across the endoplasmic reticulum membraneQ39507809
Nuclear and cytoplasmic glycosylation: novel saccharide linkages in unexpected placesQ39572613
Topography of glycosylation in the rough endoplasmic reticulum and Golgi apparatusQ39664972
Mechanisms of cellular nutritionQ39726959
Transcriptional selectivity of viral genes in mammalian cellsQ39743207
Alpha 2-macroglobulinQ40103351
Protein kinase activity in hepatitis B virusQ40307160
Plasmid integration, amplification and cytogenetics in CHO cells: questions and commentsQ40626388
Peroxisome targeting signal of rat liver acyl-coenzyme A oxidase resides at the carboxy terminusQ40644082
The IRS-1 signaling systemQ40682085
Getting the glycosylation right: implications for the biotechnology industryQ41176922
Super-CHO-A cell line capable of autocrine growth under fully defined protein-free conditionsQ41240981
Removal of sialic acid from a glycoprotein in CHO cell culture supernatant by action of an extracellular CHO cell sialidaseQ41327511
Effect of different cell culture conditions on the polypeptide integrity and N-glycosylation of a recombinant model glycoproteinQ41334135
Expression of FSH in CHO cells. II. Stimulation of hFSH expression levels by defined medium supplementsQ41371103
N-linked glycosylation of tissue plasminogen activator in Namalwa cellsQ41375509
Problems with serum-free production of antithrombin III regarding proteolytic activity and product qualityQ41472630
Growth and interferon-gamma production in batch culture of CHO cellsQ41504941
Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cellsQ41505031
Effect of lipid supplements on the production and glycosylation of recombinant interferon-gamma expressed in CHO cellsQ41505038
The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactinQ41505044
The effect of the dilution rate on CHO cell physiology and recombinant interferon-gamma production in glucose-limited chemostat cultureQ41514657
Enhancer-controlled expression of the simian virus 40 T-antigen in the green alga AcetabulariaQ41580368
Analysis of the distribution of charged residues in the N-terminal region of signal sequences: implications for protein export in prokaryotic and eukaryotic cells.Q41581591
Glucose-limited chemostat culture of Chinese hamster ovary cells producing recombinant human interferon-gammaQ41640254
High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable markerQ41642360
Purification and characterization of three forms of differently glycosylated recombinant human granulocyte-macrophage colony-stimulating factorQ41685681
Stable, high-level expression of a carcinoembryonic antigen-encoding cDNA after transfection and amplification with the dominant and selectable asparagine synthetase markerQ41714831
Sparged animal cell bioreactors: mechanism of cell damage and Pluronic F-68 protectionQ41724364
Adaptation to non-ammoniagenic medium and selective substrate feeding lead to enhanced yields in animal cell culturesQ41729779
A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cellsQ41758371
Perturbation of cellular calcium blocks exit of secretory proteins from the rough endoplasmic reticulumQ42831932
Analysis of sequence requirements for protein tyrosine sulfationQ42842888
Effect of tunicamycin on IgM, IgA, and IgG secretion by mouse plasmacytoma cellsQ43728212
Mammalian expression vector with two multiple cloning sites for expression of two foreign genes.Q44050465
Selection and coamplification of heterologous genes in mammalian cellsQ44671107
Glycosidase activities in Chinese hamster ovary cell lysate and cell culture supernatantQ44743740
The cloning and reintroduction into animal cells of a functional CAD gene, a dominant amplifiable genetic markerQ44754199
The functional domains of coagulation factor VIII:C.Q45886539
Alteration of terminal glycosylation sequences on N-linked oligosaccharides of Chinese hamster ovary cells by expression of beta-galactoside alpha 2,6-sialyltransferase.Q46007488
Effect of ammonium ion and extracellular pH on hybridoma cell metabolism and antibody productionQ46922872
A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirusQ48378635
Selective overproduction of adenosine deaminase in cultured mouse cells.Q54057483
Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev functionQ58611466
High level expression of the humanized monoclonal antibody Campath-1H in Chinese hamster ovary cellsQ67527852
P304page(s)Unit5.9
P577publication date2001-05-01
P1433published inCurrent protocols in protein science / editorial board John E. Coligan ... [et al.]Q26841923
P1476titleOverview of protein expression by mammalian cells
P478volumeChapter 5