scholarly article | Q13442814 |
P50 | author | Jiří Vachtenheim | Q59694164 |
P2093 | author name string | Eva Sloncová | |
Martina Vojtechová | |||
Zdena Tuhácková | |||
Dana Kucerová | |||
Jolana Turecková | |||
P2860 | cites work | Rapamycin-resistant phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in v-SRC-transformed hamster fibroblasts | Q39438481 |
Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition | Q40164038 | ||
Regulation of c-Src activity by the expression of wild-type v-Src and its kinase-dead double Y416F-K295N mutant | Q40217084 | ||
Receptor association and tyrosine phosphorylation of S6 kinases. | Q40287436 | ||
Active Src elevates the expression of beta-catenin by enhancement of cap-dependent translation | Q40415667 | ||
Initiation factor eIF2B not p70 S6 kinase is involved in the activation of the PI‐3K signalling pathway induced by the v‐src oncogene | Q40647038 | ||
The Src-family tyrosine kinase inhibitor PP1 interferes with the activation of ribosomal protein S6 kinases | Q40731630 | ||
Insulin-like growth factor-mediated muscle differentiation: collaboration between phosphatidylinositol 3-kinase-Akt-signaling pathways and myogenin | Q40786763 | ||
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase | Q42524332 | ||
Construction and characterization of a conditionally active version of the serine/threonine kinase Akt. | Q42829358 | ||
Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin. | Q45213258 | ||
Complexity of the TOR signaling network | Q46975015 | ||
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 | ||
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase | Q24300915 | ||
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex | Q24316314 | ||
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning | Q24320102 | ||
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling | Q24551043 | ||
Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase | Q24564747 | ||
AKT/PKB signaling: navigating downstream | Q24657857 | ||
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer | Q27824855 | ||
TOR signaling in growth and metabolism | Q27860757 | ||
Regulation of Akt/PKB activation by tyrosine phosphorylation | Q28205568 | ||
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses | Q28240102 | ||
Rheb binds and regulates the mTOR kinase | Q28247033 | ||
Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase | Q28251385 | ||
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase | Q28251762 | ||
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB | Q28306356 | ||
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb | Q28646935 | ||
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt | Q29547767 | ||
Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation | Q30164872 | ||
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy | Q34306865 | ||
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. | Q34443426 | ||
In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells | Q34582817 | ||
Cellular transformation and activation of the phosphoinositide-3-kinase-Akt cascade by the ETV6-NTRK3 chimeric tyrosine kinase requires c-Src | Q34616022 | ||
Signaling control of mRNA translation in cancer pathogenesis | Q35750101 | ||
Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation. | Q36695924 | ||
A new mutational AKTivation in the PI3K pathway | Q36907930 | ||
P433 | issue | 2 | |
P304 | page(s) | 99-107 | |
P577 | publication date | 2008-02-01 | |
P1433 | published in | Neoplasia | Q2962042 |
P1476 | title | Regulation of mTORC1 signaling by Src kinase activity is Akt1-independent in RSV-transformed cells | |
P478 | volume | 10 |
Q41878889 | Adaptive metabolic rewiring to chronic SFK inhibition |
Q39582921 | Albumin-induced epithelial-mesenchymal transition and ER stress are regulated through a common ROS-c-Src kinase-mTOR pathway: effect of imatinib mesylate |
Q34135475 | Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression |
Q41910140 | Common themes in PrP signaling: the Src remains the same |
Q24628746 | Dinosaurs and ancient civilizations: reflections on the treatment of cancer |
Q52684003 | Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification. |
Q39601708 | Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes. |
Q42501870 | Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris |
Q38807880 | Inhibition of epithelial-mesenchymal transition in bladder cancer cells via modulation of mTOR signalling |
Q33648488 | Initiation factor eIF2-independent mode of c-Src mRNA translation occurs via an internal ribosome entry site |
Q37687424 | Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation |
Q37296909 | MiR-424/503-mediated Rictor upregulation promotes tumor progression |
Q39579714 | MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways |
Q28389251 | NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease |
Q30484000 | Neoplasia: the second decade |
Q35845746 | Prostate specific G protein coupled receptor is associated with prostate cancer prognosis and affects cancer cell proliferation and invasion |
Q41952230 | Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets |
Q34241749 | RACK1 is a ribosome scaffold protein for β-actin mRNA/ZBP1 complex |
Q39544647 | Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway |
Q37996268 | Signalling pathways passing Src in pancreatic endocrine tumours: relevance for possible combined targeted therapies. |
Q37576208 | Src tyrosine kinase signaling antagonizes nuclear localization of FOXO and inhibits its transcription factor activity |
Q37687335 | Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and src activity using an active component of antrodia cinnamomea mycelia |
Q64114981 | Targeting mTOR and Src restricts hepatocellular carcinoma growth in a novel murine liver cancer model |
Q91698499 | The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein |
Q37478602 | The War on Cancer rages on. |
Q34493472 | The role of c-Src in integrin (α6β4) dependent translational control |
Search more.