Ovarian cancer patients at high risk of BRCA mutation: the constitutional genetic characterization does not change prognosis.

scientific article published on February 2016

Ovarian cancer patients at high risk of BRCA mutation: the constitutional genetic characterization does not change prognosis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10689-016-9873-9
P698PubMed publication ID26833043

P50authorFrancois EisingerQ53791638
Patrice ViensQ57015162
Renaud SabatierQ82068977
Magali ProvansalQ112902541
P2093author name stringHagay Sobol
Cornel Popovici
Eric Lambaudie
Emmanuelle Charaffe-Jauffret
Tetsuro Noguchi
Laetitia Rabayrol
Jessica Moretta
Doriane Livon
Elisabeth Cherau
Elise Lavit
P2860cites workAverage risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studiesQ24531993
BRCAness: finding the Achilles heel in ovarian cancerQ24630872
Meta-analysis of BRCA1 and BRCA2 penetranceQ24654786
TP53 mutations in ovarian carcinomas from sporadic cases and carriers of two distinct BRCA1 founder mutations; relation to age at diagnosis and survivalQ24812743
Effect of Screening on Ovarian Cancer MortalityQ26253810
Clinical epidemiology of epithelial ovarian cancer in the UKQ26822648
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriersQ27851474
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancerQ27851709
Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomasQ27852671
Combination cediranib and olaparib versus olaparib alone for women with recurrent platinum-sensitive ovarian cancer: a randomised phase 2 studyQ27853070
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategyQ27860519
Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaborationQ28222847
Hallmarks of 'BRCAness' in sporadic cancersQ29618825
Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group studyQ33348987
The role of BRCA status on the prognosis of patients with epithelial ovarian cancer: a systematic review of the literature with a meta-analysisQ33553318
Integrated analysis of germline and somatic variants in ovarian cancer.Q33630954
Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.Q34049228
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancerQ34049234
Breast-cancer risk in families with mutations in PALB2Q34148873
Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.Q34422265
Effects of BRCA1- and BRCA2-related mutations on ovarian and breast cancer survival: a meta-analysisQ34860429
A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPROQ35445946
Improved survival in BRCA2 carriers with ovarian cancerQ35828679
Improved survival in non-Ashkenazi Jewish ovarian cancer patients with BRCA1 and BRCA2 gene mutations.Q35848153
Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survivalQ35914568
BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study GroupQ36145443
Mutation screening of RAD51C in high-risk breast and ovarian cancer familiesQ36162179
Hereditary ovarian cancer.Q36235943
'BRCAness' and its implications for platinum action in gynecologic cancerQ36380704
Are there candidates for high-dose chemotherapy in ovarian carcinoma?Q36468856
Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancerQ36763684
Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group StudyQ36912591
Sporadic epithelial ovarian cancer: clinical relevance of BRCA1 inhibition in the DNA damage and repair pathwayQ37203864
Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer.Q37263790
Risks and benefits of screening asymptomatic women for ovarian cancer: a systematic review and meta-analysisQ38119029
Ovarian cancer: risk factors, treatment and managementQ38143316
PARP inhibitors in ovarian cancer: current status and future promiseQ38194324
Survival of BRCA1 breast and ovarian cancer patients: a population-based study from southern SwedenQ38503154
Survival in epithelial ovarian cancer: a multivariate analysis incorporating BRCA mutation status and platinum sensitivity.Q39816174
Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancerQ40673230
BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal breast cancerQ42477044
Failure of BRCA1 dysfunction to alter ovarian cancer survival.Q44044626
Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancerQ44461877
Preoperative genetic testing affects surgical decision making in breast cancer patientsQ44683977
Survival analysis in familial ovarian cancer, a case control studyQ45280874
The different impact of BRCA mutations on the survival of epithelial ovarian cancer patients: a retrospective single-center experience.Q45391582
Neoadjuvant chemotherapy followed by interval cytoreductive surgery in patients with unresectable, advanced stage epithelial ovarian cancer: a single centre experienceQ45822470
BRCA1 promoter region hypermethylation in ovarian carcinoma: a population-based studyQ46119283
Improved survival in women with BRCA-associated ovarian carcinomaQ46693199
Chemosensitivity and outcome of BRCA1- and BRCA2-associated ovarian cancer patients after first-line chemotherapy compared with sporadic ovarian cancer patientsQ46799385
Analysis of PALB2 in a cohort of Italian breast cancer patients: identification of a novel PALB2 truncating mutation.Q50961264
Response-guided neoadjuvant chemotherapy for breast cancer.Q52882601
Predictability of the survival of patients with advanced ovarian cancer.Q53409532
Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial.Q53668957
Effect of BRCA Mutations on the Length of Survival in Epithelial Ovarian TumorsQ57250723
Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibilityQ57305903
BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genesQ57309394
“BRCAness” Syndrome in Ovarian Cancer: A Case-Control Study Describing the Clinical Features and Outcome of Patients With Epithelial Ovarian Cancer Associated WithBRCA1andBRCA2MutationsQ57694467
Cancer Risk Estimates for BRCA1 Mutation Carriers Identified in a Risk Evaluation ProgramQ57903119
Ovarian cancer survival in Ashkenazi Jewish patients with BRCA1 and BRCA2 mutationsQ59689022
BRCA1/2 mutations and expression: Response to platinum chemotherapy in patients with advanced stage epithelial ovarian cancerQ62112707
Clinicopathologic features of BRCA-linked and sporadic ovarian cancerQ73782102
Clinical features of ovarian cancer in Japanese women with germ-line mutations of BRCA1Q74361088
Inactivation of BRCA1 and BRCA2 in ovarian cancerQ74801177
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancerQ80423982
Overall survival in BRCA-associated ovarian cancer: case-control study of an Italian seriesQ83407749
[Hereditary forms of ovarian cancer]Q83505157
Histological response is not a prognostic factor after neoadjuvant chemotherapy in advanced-stage ovarian cancer with no residual diseaseQ84534751
BRCA1/2 mutation status is an independent factor of improved survival for advanced (stage III-IV) ovarian cancerQ85363448
P433issue4
P921main subjectovarian cancerQ172341
P304page(s)497-506
P577publication date2016-10-01
P1433published inFamilial CancerQ15761917
P1476titleOvarian cancer patients at high risk of BRCA mutation: the constitutional genetic characterization does not change prognosis
P478volume15

Reverse relations

cites work (P2860)
Q55377222Association of BRCA1/2 mutations with ovarian cancer prognosis: An updated meta-analysis.
Q90966998BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer
Q37702214Prognostic significance of BRCA mutations in ovarian cancer: an updated systematic review with meta-analysis

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