Highly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection

scientific article published on 10 September 2017

Highly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MICINF.2017.08.010
P932PMC publication ID7110499
P698PubMed publication ID28903071

P50authorWanbo TaiQ89600294
Yusen ZhouQ98175621
P2093author name stringLei He
Lanying Du
Shibo Jiang
Yan Guo
Guangyu Zhao
Shihui Sun
Pei Li
Nianping Song
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Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypesQ24614628
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High-throughput recombinant protein expression in Escherichia coli: current status and future perspectivesQ28066811
Universal influenza virus vaccines and therapeutic antibodiesQ30151337
Pandemic preparedness and response--lessons from the H1N1 influenza of 2009.Q30210593
M2e-based universal influenza A vaccineQ30227479
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An H5N1-based matrix protein 2 ectodomain tetrameric peptide vaccine provides cross-protection against lethal infection with H7N9 influenza virus.Q30375268
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An H5N1 M2e-based multiple antigenic peptide vaccine confers heterosubtypic protection from lethal infection with pandemic 2009 H1N1 virusQ30391315
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Protection against multiple influenza A virus strains induced by candidate recombinant vaccine based on heterologous M2e peptides linked to flagellinQ35209148
Epitope Mapping of Avian Influenza M2e Protein: Different Species Recognise Various EpitopesQ36065047
Evaluation of the immunogenicity and protective effects of a trivalent chimeric norovirus P particle immunogen displaying influenza HA2 from subtypes H1, H3 and B.Q36970026
Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunityQ37366744
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Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape MutantsQ37512915
Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvantQ39844962
Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Outflanking Antibody Immunodominance on the Road to Universal Influenza VaccinationQ40140614
Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Toward a Universal Influenza Virus Vaccine: Potential Target Antigens and Critical Aspects for Vaccine DevelopmentQ40140618
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Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challengeQ40157020
High immunogenicity of plant-produced candidate influenza vaccine based on the M2e peptide fused to flagellin.Q40165332
Preliminary Epidemiology of Human Infections with Highly Pathogenic Avian Influenza A(H7N9) Virus, China, 2017.Q40172945
A recombinant receptor-binding domain of MERS-CoV in trimeric form protects human dipeptidyl peptidase 4 (hDPP4) transgenic mice from MERS-CoV infectionQ40503787
High copy numbers and N terminal insertion position of influenza A M2E fused with hepatitis B core antigen enhanced immunogenicityQ40556139
M2-based influenza vaccines: recent advances and clinical potentialQ40571808
P433issue12
P304page(s)641-647
P577publication date2017-09-10
P1433published inMicrobes and InfectionQ15760242
P1476titleHighly conserved M2e and hemagglutinin epitope-based recombinant proteins induce protection against influenza virus infection
P478volume19

Reverse relations

cites work (P2860)
Q56989454Combination of M2e peptide with stalk HA epitopes of influenza A virus enhances protective properties of recombinant vaccine
Q54239201Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes.
Q89511342Plant-Produced Recombinant Influenza A Virus Candidate Vaccine Based on Flagellin Linked to Conservative Fragments of M2 Protein and Hemagglutintin
Q90043367Protective immunity against influenza virus challenge by norovirus P particle-M2e and HA2-AtCYN vaccines in chickens
Q92905919Targeting M2e to DEC-205 induces an enhanced serum antibody-dependent heterosubtypic protection against influenza A virus infection
Q47548866Towards a universal influenza vaccine: different approaches for one goal

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