Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection.

scientific article published on 10 August 2017

Fas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-017-08578-7
P932PMC publication ID5552859
P698PubMed publication ID28798348

P50authorAnna MalyshkinaQ74312981
Kim J HasenkrugQ89268235
Hendrik StreeckQ28032204
Kathrin GibbertQ41810117
P2093author name stringUlf Dittmer
Annette Paschen
Gennadiy Zelinskyy
Simone Schimmer
Sonja Windmann
Elisabeth Littwitz-Salomon
P2860cites workCytotoxic CD4 T cells in viral hepatitisQ80091867
Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cellsQ84724561
Cytotoxic CD4 T cells in antiviral immunityQ21296742
Molecular and cellular insights into T cell exhaustionQ26800047
Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse modelQ27003380
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progressionQ29618956
Regulatory T cells suppress antiviral immune responses and increase viral loads during acute infection with a lymphotropic retrovirusQ33497925
Mice of the resistant H-2(b) haplotype mount broad CD4(+) T cell responses against 9 distinct Friend virus epitopesQ33708553
Cell death induced by the Fas/Fas ligand pathway and its role in pathologyQ33717488
Critical role for CD4(+) T cells in controlling retrovirus replication and spread in persistently infected miceQ33783475
Reovirus-induced apoptosis is mediated by TRAILQ33810960
CD4(+) T cells and gamma interferon in the long-term control of persistent friend retrovirus infectionQ33834466
The role of CD4 and CD8 T cells in recovery and protection from retroviral infection: lessons from the Friend virus modelQ33954433
Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell MemoryQ34190038
Essential roles for CD8+ T cells and gamma interferon in protection of mice against retrovirus-induced immunosuppressionQ34327211
How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?Q34418112
Functional significance of the perforin/granzyme cell death pathwayQ34931863
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemiaQ34997704
Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loadsQ35067219
Revisiting immune exhaustion during HIV infectionQ35131530
CD134 plus CD137 dual costimulation induces Eomesodermin in CD4 T cells to program cytotoxic Th1 differentiationQ35228053
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infectionQ35241486
TRAIL and apoptosis induction by TNF-family death receptors.Q35591708
PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell KillingQ35814368
Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirusQ35838192
TRAIL-mediated apoptosis in HIV-1-infected macrophages is dependent on the inhibition of Akt-1 phosphorylationQ35842625
Cooperativity of HIV-Specific Cytolytic CD4 T Cells and CD8 T Cells in Control of HIV ViremiaQ35861240
Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotypeQ36340873
Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivoQ36375248
The central role of CD4(+) T cells in the antitumor immune responseQ36401381
Multiplicity of virus-encoded helper T-cell epitopes expressed on FBL-3 tumor cellsQ36650857
Immune control and prevention of chronic Friend retrovirus infectionQ36664635
Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.Q36684398
CD4+ T cells develop antiretroviral cytotoxic activity in the absence of regulatory T cells and CD8+ T cellsQ36827240
Expanding roles for CD4⁺ T cells in immunity to viruses.Q37150560
T cell immunity in acute HIV-1 infection.Q37789345
Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infectionQ38812394
CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor ActivityQ38816507
Ectopic expression of a T-box transcription factor, eomesodermin, renders CD4(+) Th cells cytotoxic by activating both perforin- and FasL-pathwaysQ39378312
Natural regulatory T cells inhibit production of cytotoxic molecules in CD8⁺ T cells during low-level Friend retrovirus infectionQ39419894
Role of TRAIL and IFN-gamma in CD4+ T cell-dependent tumor rejection in the anterior chamber of the eye.Q40636781
Biological behavior of malignant melanoma cells correlated to their survival in vivoQ41067629
Distinct roles of NK cells in viral immunity during different phases of acute Friend retrovirus infectionQ41810050
The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen controlQ42910302
Effector CD4 and CD8 T cells and their role in the tumor microenvironmentQ42952683
Strong ability of Nef-specific CD4+ cytotoxic T cells to suppress human immunodeficiency virus type 1 (HIV-1) replication in HIV-1-infected CD4+ T cells and macrophagesQ43096910
Independent roles of perforin, granzymes, and Fas in the control of Friend retrovirus infection.Q45165004
The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell responseQ45382135
Dynamics of CD8+ T cell responses during acute and chronic lymphocytic choriomeningitis virus infectionQ45401031
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)7785
P577publication date2017-08-10
P1433published inScientific ReportsQ2261792
P1476titleFas Ligand-mediated cytotoxicity of CD4+ T cells during chronic retrovirus infection
P478volume7

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cites work (P2860)
Q92005460Friend retrovirus studies reveal complex interactions between intrinsic, innate and adaptive immunity
Q99571941Impaired Cytotoxic CD8+ T Cell Response in Elderly COVID-19 Patients
Q49979151Regulatory T cells in retroviral infections
Q59792386Treatment duration with immune-based therapies in Cancer: an enigma

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