Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells

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Molecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1034661851
P356DOI10.1007/S11064-007-9369-Y
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s11064-007-9369-y
P698PubMed publication ID17616815

P2093author name stringNaren L Banik
Surajit Karmakar
Swapan K Ray
P2860cites workBax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondriaQ22008484
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascadeQ24311006
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2Q24534641
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibitionQ28115131
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteinsQ28117928
Inositol hexakisphosphate blocks tumor cell growth by activating apoptotic machinery as well as by inhibiting the Akt/NFkappaB-mediated cell survival pathwayQ33185583
Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cellsQ33200961
Mammary tumor inhibition by IP6: a review.Q33811273
Metabolism and cellular functions of IP6: a reviewQ33811301
Progress in cancer chemoprevention: development of diet-derived chemopreventive agentsQ33866231
The age of cancerQ34088387
Decreased apoptosis in the brain and premature lethality in CPP32-deficient miceQ34408475
Phytic acid in wheat bran affects colon morphology, cell differentiation and apoptosisQ34509851
Inositol hexaphosphate represses telomerase activity and translocates TERT from the nucleus in mouse and human prostate cancer cells via the deactivation of Akt and PKCalphaQ34566573
Inositol hexaphosphate inhibits growth and induces G1 arrest and apoptotic death of androgen-dependent human prostate carcinoma LNCaP cellsQ34928606
Isothiocyanates as novel cytotoxic and cytostatic agents: molecular pathway on human transformed and non-transformed cellsQ35864044
Caspase-dependent and -independent cell death pathways after DNA damage (Review).Q36217501
5-Aminolevulinic acid-based photodynamic therapy suppressed survival factors and activated proteases for apoptosis in human glioblastoma U87MG cellsQ36871575
Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cellsQ40183934
Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cellsQ40236946
Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphaneQ40269357
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.Q40291410
Inositol hexaphosphate (IP6) inhibits cellular proliferation in melanomaQ40300223
Inositol hexaphosphate (IP6): a novel treatment for pancreatic cancerQ40416655
Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibitionQ40515218
Anti-angiogenic activity of inositol hexaphosphate (IP6).Q40528072
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.Q40662030
Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosisQ40671716
IP6 in treatment of liver cancer. II. Intra-tumoral injection of IP6 regresses pre-existing human liver cancer xenotransplanted in nude miceQ40980043
IP6 in treatment of liver cancer. I. IP6 inhibits growth and reverses transformed phenotype in HepG2 human liver cancer cell lineQ40980051
Novel anticancer function of inositol hexaphosphate: inhibition of human rhabdomyosarcoma in vitro and in vivo.Q41023356
Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosisQ41154412
Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid).Q41532307
IP6: a novel anti-cancer agentQ41551899
Effects of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell lineQ41614183
Methamphetamine causes differential regulation of pro-death and anti-death Bcl-2 genes in the mouse neocortexQ43693008
Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexesQ44381282
Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamateQ46965677
Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury.Q48785790
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.Q53395761
Impairment of erbB1 receptor and fluid-phase endocytosis and associated mitogenic signaling by inositol hexaphosphate in human prostate carcinoma DU145 cells.Q53402962
Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cellsQ53462199
Simultaneous Degradation of αII- and βII-Spectrin by Caspase 3 (CPP32) in Apoptotic CellsQ58115643
Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ storesQ64379412
Antitumor activity of phytic acid (inositol hexaphosphate) in murine transplanted and metastatic fibrosarcoma, a pilot studyQ68026541
Inositol hexakisphosphate stimulates 45Ca2+ influx in purified mitochondria from rat liverQ68271141
Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 ratsQ68640945
Inositol hexakisphosphate (phytic acid) enhances Ca2+ influx and D-[3H]aspartate release in cultured cerebellar neuronsQ69702272
Calcium-activated neutral proteinase in rat brain myelin and subcellular fractionsQ69849079
Novel anti-cancer functions of IP6: growth inhibition and differentiation of human mammary cancer cell lines in vitroQ73093437
bcl2, p53 and bax in thyroid tumors and their relation to apoptosisQ77188573
P433issue12
P921main subjectglioblastomaQ282142
P304page(s)2094-2102
P577publication date2007-07-07
P1433published inNeurochemical ResearchQ15716728
P1476titleMolecular mechanism of inositol hexaphosphate-mediated apoptosis in human malignant glioblastoma T98G cells
P478volume32

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cites work (P2860)
Q40013683Adherence to the Dietary Approaches to Stop Hypertension-style diet in relation to glioma: a case-control study
Q28078208Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
Q39817583Characterization of the serum metabolome following radiation treatment in patients with high-grade gliomas
Q39064313Cisplatin associated with LY294002 increases cytotoxicity and induces changes in transcript profiles of glioblastoma cells.
Q94503829Fluoresceinated Aminohexanol Tethered Inositol Hexakisphosphate: Studies on Arabidopsis thaliana and Drosophila melanogaster and Docking with 2P1M Receptor
Q35136175Koenimbin, a natural dietary compound of Murraya koenigii (L) Spreng: inhibition of MCF7 breast cancer cells and targeting of derived MCF7 breast cancer stem cells (CD44(+)/CD24(-/low)): an in vitro study.
Q35149953N-(4-Hydroxyphenyl) Retinamide Potentiated Anti-tumor Efficacy of Genistein in Human Ewing's Sarcoma Xenografts
Q38766064Phytic Acid: From Antinutritional to Multiple Protection Factor of Organic Systems
Q44888065Review of Natural Product-Derived Compounds as Potent Antiglioblastoma Drugs

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