Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes

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Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/1439-7633(20020104)3:1<61::AID-CBIC61>3.0.CO;2-I
P8608Fatcat IDrelease_au6h7duap5b27e5vt7lyffopr4
P698PubMed publication ID17590955

P2093author name stringCarlos Alonso
Carmen Navarro-Ranninger
Annie Schwartz
José M Pérez
Miguel A Fuertes
Eva I Montero
Jean M Malinge
Marc Leng
P2860cites workA new method for sequencing DNAQ24605576
Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposureQ28260454
X-Ray structure of cytotoxic trans-[PtCl(2)(dimethylamine)(isopropylamine)]: interstrand cross-link efficiency, DNA sequence specificity, and inhibition of the B-Z transition.Q31402705
Current status of the development of trans-platinum antitumor drugsQ33998355
DNA double helix promotes a linkage isomerization reaction in trans-diamminedichloroplatinum(II)-modified DNA.Q35685036
Sequence preferences of DNA interstrand crosslinking agents: quantitation of interstrand crosslink locations in DNA duplex fragments containing multiple crosslinkable sitesQ35761618
DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residuesQ36351000
Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.Q37422551
Chemical versatility of transplatin monofunctional adducts within multiple site-specifically platinated DNA.Q38344920
Quantitative estimation of cisplatin-induced DNA interstrand cross-links and their repair in mammalian cells: relationship to toxicityQ39681354
Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relation with the clinical inefficiency of transplatinQ40394674
Apoptosis induction and inhibition of H-ras overexpression by novel trans-[PtCl2(isopropylamine)(amine')] complexesQ40907859
Preparation and characterization of novel trans-[PtCl(2)(amine)(isopropylamine)] compounds: cytotoxic activity and apoptosis induction in ras-transformed cellsQ40924467
Increased gene specific repair of cisplatin induced interstrand crosslinks in cisplatin resistant cell lines, and studies on carrier ligand specificityQ41146945
Structure, Recognition, and Processing of Cisplatin-DNA Adducts.Q55035583
DNA Adducts of cis-Diamminedichloroplatinum(II) and Its Trans Isomer Inhibit RNA Polymerase II Differentially in VivoQ71786418
DNA conformational change produced by the site-specific interstrand cross-link of trans-diamminedichloroplatinum(II)Q72551702
Cellular and molecular determinants of cisplatin resistanceQ77809152
P433issue1
P304page(s)61-67
P577publication date2002-01-01
P1433published inChemBioChemQ634395
P1476titleApoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes
P478volume3

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cites work (P2860)
Q35565981Pharmacological Modulation of Poly(ADP-ribose) Polymerase-Mediated Cell Death: Exploitation in Cancer Chemotherapy
Q37276239Promotion of DNA strand breaks, interstrand cross-links and apoptotic cell death in A2780 human ovarian cancer cells by transplatinum planar amine complexes
Q37576021Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm
Q34565192Ruthenium polypyridyl complexes and their modes of interaction with DNA: is there a correlation between these interactions and the antitumor activity of the compounds?
Q46865307Syntheses and characterization of vitamin B12-Pt(II) conjugates and their adenosylation in an enzymatic assay
Q28066801The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
Q40089378Trans-platinum(II) complexes with cyclohexylamine as expectator ligand induce necrosis in tumour cells by inhibiting DNA synthesis and RNA transcription.

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