The investigation of CD4+T-cell functions in primary HIV infection with antiretroviral therapy

scientific article published on July 2017

The investigation of CD4+T-cell functions in primary HIV infection with antiretroviral therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/MD.0000000000007430
P932PMC publication ID5515751
P698PubMed publication ID28700479

P2093author name stringJing Liu
Yu Sun
Hong Shang
Junjie Xu
Yongjun Jiang
Haibo Ding
Zhenxing Chu
Tian Tang
Xiaoxu Han
Zining Zhang
Yajing Fu
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Systemic effects of inflammation on health during chronic HIV infectionQ33577551
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortalityQ33618542
The dual impact of HIV-1 infection and aging on naïve CD4 T-cells: additive and distinct patterns of impairmentQ33813372
Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infectionQ33947817
Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cellsQ34059612
Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.Q34126302
T Cell Activation Is Associated with Lower CD4+T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral TherapyQ34193786
Immune activation and HIV persistence: implications for curative approaches to HIV infectionQ34351320
CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cellsQ34395160
Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infectionQ34430215
Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical stagingQ34581195
Lymphoid tissue structure and HIV-1 infection: life or death for T cellsQ34638477
Different immunological phenotypes associated with preserved CD4+ T cell counts in HIV-infected controllers and viremic long term non-progressorsQ34733986
T cell activation and senescence predict subclinical carotid artery disease in HIV-infected womenQ34764361
Changes in the risk of death after HIV seroconversion compared with mortality in the general populationQ34791057
T cell activation predicts carotid artery stiffness among HIV-infected womenQ35113323
CD4 cell count and the risk of AIDS or death in HIV-Infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHEREQ35842386
CD4+ T-cell depletion in HIV infection: killed by friendly fire?Q36223837
Immunological biomarkers predict HIV-1 viral rebound after treatment interruptionQ36250043
Impact of CD8+ T-cell activation on CD4+ T-cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapyQ36344908
Early Initiation Rather Than Prolonged Duration of Antiretroviral Therapy in HIV Infection Contributes to the Normalization of CD8 T-Cell CountsQ36402470
Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapyQ36854142
Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T-cell activationQ36930492
Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infectionQ37003624
CD4(+) T-cell depletion in HIV infection: mechanisms of immunological failureQ37059664
Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir sizeQ37187501
Antiretroviral Therapy in Primary HIV-1 Infection: Influences on Immune Activation and Gut Mucosal Barrier DysfunctionQ38602901
Race, Sex, Drug Use, and Progression of Human Immunodeficiency Virus DiseaseQ39375985
T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral TreatmentQ40716958
Elevated CD57 and CD95 expressions are associated with lower numbers of CD4⁺ recent thymic emigrants in HIV-1 infected immune responders following antiretroviral treatment.Q42252037
Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 diseaseQ43582240
Impact of treatment with raltegravir during primary or chronic HIV infection on RNA decay characteristics and the HIV viral reservoirQ44790341
Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA.Q45930407
Long-term antiretroviral therapy initiated during primary HIV-1 infection is key to achieving both low HIV reservoirs and normal T cell counts.Q45930474
A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infectionQ46280014
CD4+ cell count 6 years after commencement of highly active antiretroviral therapy in persons with sustained virologic suppression.Q50795585
Premature age-related comorbidities among HIV-infected persons compared with the general population.Q51000618
Effect of baseline- and treatment-related factors on immunologic recovery after initiation of antiretroviral therapy in HIV-1-positive subjects: results from ACTG 384.Q51797675
Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy.Q51888711
Nadir CD4+ T-cell count and numbers of CD28+ CD4+ T-cells predict functional responses to immunizations in chronic HIV-1 infection.Q53855050
Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/ L in HIV Type 1--Infected Individuals Receiving Potent Antiretroviral TherapyQ58075270
Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV diseaseQ73470103
Immune reconstitution in HIV-infected patientsQ79955828
Survival and proliferation of CD28- T cells during HIV-1 infection relate to the amplitude of viral replicationQ84142062
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)e7430
P577publication date2017-07-01
P1433published inMedicineQ15716652
P1476titleThe investigation of CD4+T-cell functions in primary HIV infection with antiretroviral therapy
P478volume96

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cites work (P2860)
Q93164947Effects of Early and Delayed Antiretroviral Therapy on Plasma Anti-CD4 Autoreactive IgG and Its Association With CD4+ T-Cell Recovery in Acute HIV-Infected Individuals
Q58538219Exploring an alternative explanation for the second phase of viral decay: Infection of short-lived cells in a drug-limited compartment during HAART

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