The small-intestinal Na+,d-glucose cotransporter: An asymmetric gated channel (or pore) responsive to ΔΨ

scientific article published on January 1, 1983

The small-intestinal Na+,d-glucose cotransporter: An asymmetric gated channel (or pore) responsive to ΔΨ is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/BF01871452
P953full work available at URLhttp://link.springer.com/article/10.1007/BF01871452/fulltext.html
http://link.springer.com/content/pdf/10.1007/BF01871452.pdf
http://link.springer.com/content/pdf/10.1007/BF01871452
P698PubMed publication ID6315944

P50authorGregg L. SemenzaQ1545025
P2093author name stringM. Kessler
G. Semenza
P2860cites workAmerican Journal of PhysiologyQ2160146
Protein measurement with the Folin phenol reagentQ20900776
Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myelomaQ24681545
Intracellular Aspects of the Process of Protein SynthesisQ29615237
Relationship between the Na+/H+ antiporter and Na+/substrate symport in Bacillus alcalophilusQ35321672
Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous componentsQ36204254
Mechanisms for the incorporation of proteins in membranes and organellesQ36205692
Involvement of multiple sodium ions in intestinal d-glucose transportQ36289975
Studies of the chloride transport in the gastric mucosa of the frogQ36373070
Sodium and Sugar Fluxes across the Mucosal Border of Rabbit IleumQ36387299
Demonstration of electrogenic Na+-dependent D-glucose transport in intestinal brush border membranesQ37431545
The Assembly of Proteins into Biological Membranes: The Membrane Trigger HypothesisQ38000320
Coupling in secondary transport Effect of electrical potentials on the kinetics of ion linked co-transportQ39106754
Anion transport in brush border membranes isolated from rat small intestineQ39150424
Exchange diffusion, transport, and intracellular level of amino acids in Ehrlich carcinoma cellsQ78478051
The anion transport system of the red blood cell The role of membrane protein evaluated by the use of ‘probes’Q39212270
The gradient hypothesis and other models of carrier-mediated active transportQ39619859
The molecular organization of membranesQ39888451
Kinetic properties of ion carriers and channelsQ40099714
On the mechanism of Na+-dependent glucose transportQ40120948
Secretion and membrane localization of proteins in Escherichia coli.Q40285614
Assembly of proteins into membranesQ40293663
The ADP-ATP translocation in mitochondria, a membrane potential controlled transportQ40295217
Transfer of proteins across membranesQ40313007
The Outer Membrane Proteins of Gram-Negative Bacteria: Biosynthesis, Assembly, and FunctionsQ40918877
A Hypothesis for the Role of Dithiol-Disulfide Interchange in Solute Transport and Energy-Transducing ProcessesQ41554889
Transmembrane disposition of the phlorizin binding protein of intestinal brush bordersQ41556663
The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesisQ41649513
Asymmetry of the red cell anion exchange system. Different mechanisms of reversible inhibition by N-(4-azido-2-nitrophenyl)-2-aminoethylsulfonate (NAP-taurine) at the inside and outside of the membraneQ41777946
Sodium/proton antiport in brush-border-membrane vesicles isolated from rat small intestine and kidneyQ41874027
Structural requirements for active intestinal transport. The nature of the carrier-sugar bonding at C-2 and the ring oxygen of the sugarQ41885484
Evidence for an intestinal Na+:sugar transport coupling stoichiometry of 2.0.Q42472564
The interpretation of non-hyperbolic rate curves for two-substrate enzymes. A possible mechanism for phosphofructokinaseQ42588021
Uphill transport induced by counterflowQ42945862
Similarity in effects of Na+ gradients and membrane potentials on D-glucose transport by, and phlorizin binding to, vesicles derived from brush borders of rattit intestinal mucosal cellsQ44092927
A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of d-glucose and choline transport systemsQ44133035
The basic asymmetry of Na+-dependent glycine transport in Ehrlich cellsQ44250586
Glucose Transport in Isolated Brush Border Membrane from Rat Small IntestineQ44317080
Kinetic analysis of H+/methyl beta-D-thiogalactoside symport in Saccharomyces fragilis.Q52712594
Kinetic analysis of a family of cotransport models.Q52731832
Kinetic features of cotransport mechanisms under isotope exchange conditions.Q52747960
The mechanism of Na+-dependent D-glucose transport.Q52761318
Kinetics of Na+-dependent D-glucose transportQ52821631
Partial purification of the sugar carrier of intestinal brush border membranes. Enrichment of the phlorizin-binding component by selective extractionsQ64891521
High-affinity phlorizin binding to brush border membranes from small intestine: Identity with (a part of) the glucose transport system, dependence on the Na+-gradient, partial purificationQ66902695
The Na+ gradient-dependent transport of D-glucose in renal brush border membranesQ66958101
Distribution of sulfhydryl groups in intestinal brush border membranes. Localization of side-chains essential for glucose transport and phlorizin bindingQ66971099
On the efficiency of energy conversion in sodium-driven D-glucose transport across small intestinal brush border membrane vesicles: an estimationQ66980412
Thermodynamics, the structure of integral membrane proteins, and transportQ67045000
A simple apparatus for performing short-time (1--2 seconds) uptake measurements in small volumes; its application to D-glucose transport studies in brush border vesicles from rabbit jejunum and ileumQ67338932
Energy-dependence of phlorizin binding to isolated renal microvillus membranes. Evidence concerning the mechanism of coupling between the electrochemical Na+ gradient the sugar transportQ67356895
Purification of the human intestinal brush border membraneQ68671095
Further evidence for the multiplicity of carriers for free glucalogues in hamster small intestineQ69812980
Potential-dependent D-glucose uptake by renal brush border membrane vesicles in the absence of sodiumQ70302386
Interaction of the sugar carrier of intestinal brush-border membranes with HgCl2Q70532128
Further studies of proximal tubular brush border membrane D-glucose transport heterogeneityQ70640377
Interaction of phlorizin and sodium with the renal brush-border membrane D-glucose transporter: stoichiometry and order of bindingQ70660898
Stoichiometric studies of the renal outer cortical brush border membrane D-glucose transporterQ70678761
Phlorizin as a probe of the small-intestinal Na+,D-glucose cotransporter. A modelQ70679535
Na+-dependent, potential-sensitive l-ascorbate transport across brush border membrane vesicles from kidney cortexQ70936207
Small-intestinal Na+/D-glucose cotransport. Inactivation of sugar transport and phlorizin binding by thiol-group and amino-group reagentsQ71228058
The small-intestinal sodium, D-glucose cotransporter is inserted in the brush border membrane asymmetricallyQ72001042
Na+ gradient-coupled porters of EScherichia coli share a common subunitQ72521566
The functional arrangement of the anion channel of red blood cellsQ72885432
Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: evidence from vesicle studiesQ72925253
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbiophysicsQ7100
physiologyQ521
cell biologyQ7141
P1104number of pages30
P304page(s)27-56
P577publication date1983-01-01
P1433published inJournal of Membrane BiologyQ6295550
P1476titleThe small-intestinal Na+,d-glucose cotransporter: An asymmetric gated channel (or pore) responsive to ΔΨ
P478volume76

Reverse relations

cites work (P2860)
Q52671272A new method for determination of relative ion permeabilities in isolated cells.
Q28306205Adaptation of intestinal nutrient transport in health and disease. Part I
Q70724850Allosterism and Na(+)-D-glucose cotransport kinetics in rabbit jejunal vesicles: compatibility with mixed positive and negative cooperativities in a homo- dimeric or tetrameric structure and experimental evidence for only one transport protein invol
Q43822264Amino acid transport by intestinal brush border vesicles of a marine fish, Boops salpa
Q38159655Comments and experiments on the kinetics of Na+ gradient-coupled glucose transport as found in rabbit jejunal brush-border membrane vesicles
Q52525143Computer analysis reveals changes in renal Na+-glucose cotransporter in diabetic rats.
Q39499492Cotransport systems for inorganic sulfate and phosphate in small intestine and renal proximal tubule
Q52650650Current-voltage relations of sodium-coupled sugar transport across the apical membrane of Necturus small intestine.
Q69037034D(-)3-hydroxybutyrate cotransport with Na in rat renal brush border membrane vesicles
Q71337937Demonstration of sodium-dependent, electrogenic substrate transport in rat small intestinal brush border membrane vesicles by a cyanine dye
Q30990921Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1
Q67957632Effects of pH, potential, chloride and furosemide on passive Na+ and K+ effluxes from human red blood cells
Q43689174Electrogenic properties of the cloned Na+/glucose cotransporter: I. Voltage-clamp studies
Q46023336Electrogenic properties of the cloned Na+/glucose cotransporter: II. A transport model under nonrapid equilibrium conditions.
Q68967362Electrogenic properties of the sodium-alanine cotransporter in pancreatic acinar cells: I. Tight-seal whole-cell recordings
Q52653519Electrogenic properties of the sodium-alanine cotransporter in pancreatic acinar cells: II. Comparison with transport models.
Q41919198Electrogenicity of phosphate transport by renal brush-border membranes
Q28609241Forging the link between structure and function of electrogenic cotransporters: the renal type IIa Na+/Pi cotransporter as a case study
Q64963684Growth factor effects on membrane transport: uptake studies using cell cultures and isolated membrane vesicles.
Q67895549Heterogeneity in the effects of membrane potentials on pantothenate and glucose uptakes by rabbit renal apical membranes
Q68418914Intracellular sodium in proximal tubules of diabetic rats. Role of glucose
Q43828189Involvement of active transport systems in the mobilization of cadmium by dithiocarbamates in vivo
Q44895716Irreversible inhibition of renal Na(+)-Pi cotransporter by alpha-bromophosphonoacetic acid
Q35578120Ischemia induces surface membrane dysfunction. Mechanism of altered Na+-dependent glucose transport
Q52671259Kinetic analysis of mechanism of intestinal Na+-dependent sugar transport.
Q71397931Kinetics of sodium D-glucose cotransport in bovine intestinal brush border vesicles
Q68308612Kinetics of the Na+/alanine cotransporter in pancreatic acinar cells
Q34400658Kinetics of the reverse mode of the Na+/glucose cotransporter
Q52531187Kinetics of volume-sensitive K transport in human erythrocytes: evidence for asymmetry.
Q68260461Lysine excretion by Corynebacterium glutamicum. 2. Energetics and mechanism of the transport system
Q38351490Measurements of amino acid transport in internally dialyzed giant axons
Q37910741Membrane potentials and the mechanism of intestinal Na(+)-dependent sugar transport
Q52655453Microscopic description of voltage effects on ion-driven cotransport systems.
Q41641622Na+ binding to the Na(+)-glucose cotransporter is potential dependent
Q69495101Phlorizin binding to isolated enterocytes: membrane potential and sodium dependence
Q36438697Properties of the mutant Ser-460-Cys implicate this site in a functionally important region of the type IIa Na(+)/P(i) cotransporter protein
Q43142319Reassessment of models of facilitated transport and cotransport
Q40224836Reduction of an eight-state mechanism of cotransport to a six-state model using a new computer program
Q38139847Robert F. Pitts memorial lecture. Electrophysiology of Triturus nephron: cable properties and electrogenic transport systems
Q38159657Sodium cotransport systems and the membrane potential difference
Q33907767Sodium leak pathway and substrate binding order in the Na+-glucose cotransporter
Q42976429Sodium-alanine cotransport in renal proximal tubule cells investigated by whole-cell current recording
Q69051914Stimulation of intestinal Na+/D-glucose cotransport by monoclonal antibodies
Q69715358The electrogenic, Na+-dependent I- transport system in plasma membrane vesicles from thyroid glands
Q52679044The mechanistic nature of the membrane potential dependence of sodium-sugar cotransport in small intestine.
Q34017583The molecular mechanism and potential dependence of the Na+/glucose cotransporter
Q39840394The potential dependence of the intestinal Na+-dependent sugar transporter
Q38159665The small-intestinal sodium-glucose cotransporter(s).
Q24536008Thermodynamic determination of the Na+: glucose coupling ratio for the human SGLT1 cotransporter
Q34062895Transepithelial glucose transport and Na+/K+ homeostasis in enterocytes: an integrative model
Q41196197Two substrate sites in the renal Na(+)-D-glucose cotransporter studied by model analysis of phlorizin binding and D-glucose transport measurements
Q41018421Uptake of fatty acids by jejunal mucosal cells is mediated by a fatty acid binding membrane protein
Q34168657Voltage and cosubstrate dependence of the Na-HCO3 cotransporter kinetics in renal proximal tubule cells
Q48896854Voltage and substrate dependence of the inverse transport mode of the rabbit Na(+)/glucose cotransporter (SGLT1).
Q57138945Voltage dependence of sodium-calcium exchange: predictions from kinetic models
Q50800852Voltage-clamp studies of the Na+/glucose cotransporter cloned from rabbit small intestine.
Q69398450Zinc inhibition of glucose uptake in brush border membrane vesicles from pig small intestine