DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA.

scientific article published on January 1983

DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3109/10409238309102799
P698PubMed publication ID6319080

P2093author name stringLiu LF
P433issue1
P304page(s)1-24
P577publication date1983-01-01
P1433published inCRC critical reviews in biochemistryQ27710548
P1476titleDNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA
P478volume15

Reverse relations

cites work (P2860)
Q68242691A new action for topoisomerase inhibitors
Q35594640ATP inhibits nuclear and mitochondrial type I topoisomerases from human leukemia cells
Q36122168Aggregation of DNA by analogs of spermidine; enzymatic and structural studies
Q68259271An ATP-independent catenating enzyme from the kinetoplast hemoflagellate Leishmania donovani
Q74261278Anti-topoisomerase II alpha autoantibodies in systemic sclerosis-association with pulmonary hypertension and HLA-B35
Q40516307Archaebacterial reverse gyrase cleavage-site specificity is similar to that of eubacterial DNA topoisomerases I.
Q28570763Association of DNA topoisomerase I and RNA polymerase I: a possible role for topoisomerase I in ribosomal gene transcription
Q36683177Autonomous parvovirus DNA replication requires topoisomerase I and its activity is increased during infection
Q38321795Biochemical characteristics and physiological significance of major DNA topoisomerases
Q36466122Biochemical pharmacology of anthracenediones and anthrapyrazoles
Q24627367Bioflavonoids as poisons of human topoisomerase II alpha and II beta
Q28203339Camptothecins: a review of their chemotherapeutic potential
Q72257322Can nuclear medicine predict response to chemotherapy?
Q47235346Characterisation of size variants of type I DNA topoisomerase isolated from calf thymus
Q34336896Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I.
Q40641040Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo
Q33340161Cisplatin and irinotecan (CPT-11) as second-line treatment in patients with advanced non-small cell lung cancer
Q36424076Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II.
Q41786070DNA gyrase complex with DNA: determinants for site-specific DNA breakage
Q34469617DNA loop domains in mammalian spermatozoa
Q36424250DNA topoisomerase I is essential in Drosophila melanogaster
Q40818137DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids
Q44938623DNA topoisomerase II from mammalian mitochondria is inhibited by the antitumor drugs, m-AMSA and VM-26.
Q36903197DNA topoisomerase II, genotoxicity, and cancer
Q41315281DNA topoisomerase inhibitors as antifungal agents.
Q36758354DNA topoisomerases from pathogenic fungi: targets for the discovery of antifungal drugs
Q67912294DNA-drug recognition and effects on topoisomerase II-mediated cytotoxicity. A three-mode binding model for ellipticine derivatives
Q78106623Disassembly of genome of higher eukaryotes: pulsed-field gel electrophoretic study of initial stages of chromatin and DNA degradation in rat liver and thymus nuclei by VM-26 and selected proteases
Q37576691Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome
Q40391028Effects of the antitumor drug VP16 (etoposide) on the archaebacterial Halobacterium GRB 1.7 kb plasmid in vivo
Q40079868Enzymology of DNA in Replication in Prokaryote
Q33931274Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA.
Q67486552Experimental studies on biochemical modulation targeting topoisomerase I and II in human tumor xenografts in nude mice
Q73726643Expression of DNA topoisomerase IIalpha in thyroid neoplasia
Q33642912Functional expression of a Drosophila gene in yeast: genetic complementation of DNA topoisomerase II
Q44872058Genetic recombination of homologous plasmids catalysed by cell-free extracts of topo-isomerase mutant strains of Saccharomyces cerevisiae
Q72538851Immunocytochemical detection of DNA topoisomerase type II in primary breast carcinomas: correlation with clinico-pathological features
Q37876263In vitro assays used to measure the activity of topoisomerases
Q41430324Inhibition of DNA synthesis by aphidicolin induces supercoiling in simian virus 40 replicative intermediates
Q35561732Inhibition of HeLa cell DNA topoisomerase I by ATP and phosphate
Q33931676Inhibition of calf thymus type II DNA topoisomerase by poly(ADP-ribosylation)
Q41050547Inhibition of human topoisomerase II by anti-neoplastic benzazolo[3,2-alpha]quinolinium chlorides
Q35952935Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene
Q35607477Isolation and characterization of the gene encoding Drosophila DNA topoisomerase II.
Q36213345Localization of topoisomerase II in mitotic chromosomes
Q36251195Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide
Q38349989Mechanism of inhibition of mammalian DNA topoisomerase I by heparin
Q54329609Mutational alteration of the breakage/resealing subunit of bacteriophage T4 DNA topoisomerase confers resistance to antitumor agent m-AMSA.
Q70142905Newly replicated DNA is associated with DNA topoisomerase II in cultured rat prostatic adenocarcinoma cells
Q41521938Recent advances in the discovery and development of topoisomerase inhibitors as antitumor agents
Q36892208Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells
Q37394750Replication forks are underrepresented in chromosomal DNA of Xenopus laevis embryos
Q36546741Resistance to inhibitors of DNA topoisomerases
Q37394291Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells
Q67699569Role of polyamine in the regulation of RNA synthesis in uterine nucleoli
Q34595603Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro
Q28302945Scl 70 autoantibodies from scleroderma patients recognize a 95 kDa protein identified as DNA topoisomerase I
Q39581388Structural aspects of antineoplastic agents--a new approach.
Q43733839Synthesis, topoisomerase I inhibition and antitumor cytotoxicity of 2,2':6',2"-, 2,2':6',3"- and 2,2':6',4"-terpyridine derivatives
Q67913548The effects of inhibitors of topoisomerase II and quinacrine on ultraviolet-light-induced DNA incision in normal and xeroderma pigmentosum fibroblasts
Q41341276The epsilon subunit of DNA polymerase III Is involved in the nalidixic acid-induced SOS response in Escherichia coli
Q68348279The nuclear scaffold exhibits DNA-binding sites selective for supercoiled DNA
Q54433856The production of topoisomerase II-mediated DNA cleavage in human leukemia cells predicts their susceptibility to 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA).
Q35616800Topoisomerase I identified by scleroderma 70 antisera: enrichment of topoisomerase I at the centromere in mouse mitotic cells before anaphase
Q40534060Topoisomerase I in multiple drug resistance
Q40028536Topoisomerase I inhibitors and drug resistance
Q42002540Topoisomerase I is the predominant nuclear protein from avian erythrocytes that can be covalently linked to DNA.
Q40535267Topoisomerase II in multiple drug resistance
Q34684254Topoisomerase II is a structural component of mitotic chromosome scaffolds.
Q36216632Topoisomerase II: A specific marker for cell proliferation
Q40499871Topoisomerase inhibitors. A review of their therapeutic potential in cancer
Q33894566Topostin, a novel inhibitor of mammalian DNA topoisomerase I from Flexibacter topostinus sp. nov. II. Purification and some properties of topostin
Q35354154Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents

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