Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy

scientific article published on 4 July 2017

Heart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00101-017-0329-X
P698PubMed publication ID28677016

P2093author name stringL Martin
C Thiemermann
T Schürholz
M Derwall
P2860cites workGut and sublingual microvascular effect of esmolol during septic shock in a porcine modelQ22000596
Comparison of Dopamine and Norepinephrine in the Treatment of ShockQ22250880
Bench-to-bedside review: sepsis is a disease of the microcirculationQ24800640
CD14-deficient mice are protected against lipopolysaccharide-induced cardiac inflammation and left ventricular dysfunction.Q54535260
Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart.Q54545982
Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trialQ57778873
In Vivo Expression of Proinflammatory Mediators in the Adult Heart after Endotoxin Administration: The Role of Toll‐Like Receptor–4Q59192150
Matrix metalloproteinase inhibitors attenuate endotoxemia induced cardiac dysfunction: a potential role for MMP-9Q59200919
Sepsis and Endothelial PermeabilityQ59227670
Inhibition of Mitochondrial Permeability Transition Prevents Sepsis-Induced Myocardial Dysfunction and MortalityQ59607578
Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: Comparison with dobutamine and milrinoneQ61842194
Right ventricular dysfunction and dilatation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humansQ68692688
The coronary circulation in human septic shockQ70014120
Myocardial adrenergic responsiveness after lethal and nonlethal doses of endotoxinQ70164267
Initial externalization followed by internalization of beta-adrenergic receptors in rat heart during sepsisQ71435284
Optimum left heart filling pressure during fluid resuscitation of patients with hypovolemic and septic shockQ71683096
Cutting edge: an endogenous pathway to systemic inflammatory response syndrome (SIRS)-like reactions through Toll-like receptor 4Q75197360
Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasisQ79906000
Toll-like receptor 2 mediates Staphylococcus aureus-induced myocardial dysfunction and cytokine production in the heartQ81072723
High mobility group box 1 induces a negative inotropic effect on the left ventricle in an isolated rat heart model of septic shock: a pilot studyQ81336575
In vivo Toll-like receptor 4 antagonism restores cardiac function during endotoxemiaQ82532647
Treatment of myocardial dysfunction in sepsis: the Toll-like receptor antagonist approachQ82532654
Cardiomyocyte Toll-like receptor 4 is involved in heart dysfunction following septic shock or myocardial ischemiaQ83154420
[Is there any indication for perioperative use of the pulmonary artery catheter?]Q83610683
Heparin, heparan sulfate and heparanase in inflammatory reactionsQ84845401
Effects and mechanism analysis of combined infusion by levosimendan and vasopressin on acute lung injury in rats septic shockQ87363331
Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility.Q50520671
Pathophysiologic responses of the subhuman primate in experimental septic shockQ52476552
Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.Q53541654
Sepsis and burn complicated by sepsis alter cardiac transporter expression.Q53585501
Increase of myocardial inhibitory G-proteins in catecholamine-refractory septic shock or in septic multiorgan failure.Q54180703
Norepinephrine or dopamine for the treatment of hyperdynamic septic shock?Q54238540
ICAM-1 and VCAM-1 mediate endotoxemic myocardial dysfunction independent of neutrophil accumulation.Q54290446
Effects of coronary hypotension and endotoxin on myocardial performance.Q54426326
Sepsis-induced myocardial dysfunction: pathophysiology and managementQ26751572
Mitochondrial Mechanisms in Septic CardiomyopathyQ26801508
Ventriculo-arterial decoupling in acutely altered hemodynamic statesQ26851662
Vasoactive agents for the treatment of sepsisQ28068818
The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in SepsisQ28072373
Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunctionQ28573976
The immunopathogenesis of sepsisQ29622909
Severity of cardiac impairment in the early stage of community-acquired sepsis determines worse prognosisQ30317801
Septic cardiomyopathy: hemodynamic quantification, occurrence, and prognostic implicationsQ30318473
Speckle tracking echocardiography in patients with septic shock: a case control study (SPECKSS).Q30383657
Presepsin (soluble CD14 subtype) and procalcitonin levels for mortality prediction in sepsis: data from the Albumin Italian Outcome Sepsis trialQ30726774
Myocardial dysfunction in sepsis: a large, unsolved puzzleQ33353302
New noninvasive method for assessment of left ventricular rotation: speckle tracking echocardiographyQ34467386
Role of endothelial heparanase in delayed-type hypersensitivityQ34557376
A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performanceQ34560402
Dysregulation of intracellular calcium transporters in animal models of sepsis-induced cardiomyopathyQ34725636
Vasopressin versus norepinephrine infusion in patients with septic shock.Q34756330
Levosimendan attenuates multiple organ injury and improves survival in peritonitis-induced septic shock: studies in a rat modelQ34761833
Myocardial dysfunction in the patient with sepsisQ34925777
Role of extracellular histones in the cardiomyopathy of sepsis.Q35555107
Silencing of uncoupling protein 2 by small interfering RNA aggravates mitochondrial dysfunction in cardiomyocytes under septic conditionsQ35609951
Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serumQ35646306
To beta block or not to beta block; that is the questionQ36088227
An essential role for complement C5a in the pathogenesis of septic cardiac dysfunctionQ36227873
Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shockQ36356245
Toll-like receptor 3 plays a central role in cardiac dysfunction during polymicrobial sepsisQ36825545
Toll-like receptor 9 promotes cardiac inflammation and heart failure during polymicrobial sepsisQ37019795
The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis.Q37045970
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.Q37120814
Continuous terlipressin versus vasopressin infusion in septic shock (TERLIVAP): a randomized, controlled pilot studyQ37360357
Bench-to-bedside review: Beta-adrenergic modulation in sepsis.Q37623067
Complications associated with pulmonary artery catheters: a comprehensive clinical reviewQ37706486
Proteoglycans in health and disease: the multiple roles of syndecan sheddingQ37788814
Toll-like receptor 4 stimulation initiates an inflammatory response that decreases cardiomyocyte contractilityQ37815210
Lipopolysaccharide and sepsis-associated myocardial dysfunctionQ37850260
Role of toll-like receptors in cardiovascular diseasesQ37854080
Management of myocardial dysfunction in severe sepsis.Q37867058
Characterization of cardiac dysfunction in sepsis: an ongoing challengeQ38172334
Myocardial depression in sepsis: from pathogenesis to clinical manifestations and treatmentQ38209176
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trialQ38316900
Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trialQ38443276
Levosimendan reduces mortality in patients with severe sepsis and septic shock: A meta-analysis of randomized trialsQ38533057
Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.Q39029084
Cardiac fibroblasts: contributory role in septic cardiac dysfunctionQ39200106
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.Q40367577
Detection of Myocardial Dysfunction in Septic Shock: A Speckle-Tracking Echocardiography Study.Q40511368
Is early ventricular dysfunction or dilatation associated with lower mortality rate in adult severe sepsis and septic shock? A meta-analysisQ40657906
Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.Q40733888
Impact of Dobutamine in Patients With Septic Shock: A Meta-Regression AnalysisQ40748583
Sequential N-Terminal Pro-B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin Measurements During Albumin Replacement in Patients With Severe Sepsis or Septic ShockQ40908825
Soluble Heparan Sulfate in Serum of Septic Shock Patients Induces Mitochondrial Dysfunction in Murine CardiomyocytesQ40925027
Circulating Histones Are Major Mediators of Cardiac Injury in Patients With Sepsis.Q41134828
Continuous cardiac output measurement by un-calibrated pulse wave analysis and pulmonary artery catheter in patients with septic shock.Q41343987
Myocardial Dysfunction in Severe Sepsis and Septic Shock: No Correlation With Inflammatory Cytokines in Real-life Clinical SettingQ41543244
The Role of Uncoupling Protein 2 During Myocardial Dysfunction in a Canine Model of Endotoxin ShockQ41590175
Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serumQ41903981
Evaluation of left ventricular systolic function revisited in septic shock.Q42176944
G protein and adenylate cyclase complex-mediated signal transduction in the rat heart during sepsisQ42442342
Intraaortic balloon support for myocardial infarction with cardiogenic shockQ42664790
Ivabradine: a preliminary observation for a new terapeutic role in patients with multiple organ dysfunction syndromeQ42871311
Efficacy and safety of dopamine versus norepinephrine in the management of septic shockQ43256319
Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trialQ43412778
Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsisQ43707142
Infusion of methylene blue in human septic shock: a pilot, randomized, controlled studyQ43757721
Infusion of the beta-adrenergic blocker esmolol attenuates myocardial dysfunction in septic ratsQ43995613
Association between mitochondrial dysfunction and severity and outcome of septic shockQ44074137
IL-1beta and IL-6 act synergistically with TNF-alpha to alter cardiac contractile function after burn traumaQ44188428
Postlipopolysaccharide oxidative damage of mitochondrial DNA.Q44248025
Profound but reversible myocardial depression in patients with septic shockQ44250178
Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis modelQ44290150
Protective role of PARK2/Parkin in sepsis-induced cardiac contractile and mitochondrial dysfunctionQ45793639
The Ca2+-sensitizer levosimendan improves oxidative damage, BNP and pro-inflammatory cytokine levels in patients with advanced decompensated heart failure in comparison to dobutamineQ46515116
Mechanisms of cardiac depression caused by lipoteichoic acids from Staphylococcus aureus in isolated rat heartsQ46618537
Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemiaQ46862129
High-mobility group box 1 (HMGB1) impaired cardiac excitation-contraction coupling by enhancing the sarcoplasmic reticulum (SR) Ca(2+) leak through TLR4-ROS signaling in cardiomyocytesQ46878398
The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effectsQ46902596
Influence of levosimendan on organ dysfunction in patients with severely reduced left ventricular function undergoing cardiac surgeryQ47877301
Use of a Short-Acting β1 Blocker During Endotoxemia May Reduce Cerebral Tissue Oxygenation if Hemodynamics are Depressed by a Decrease in Heart RateQ47885980
Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthasesQ47891975
Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesisQ47911806
Clinical management of the cardiovascular failure in sepsisQ48496620
Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazoleQ48642254
Competitive and noncompetitive inhibition of myocardial cytochrome C oxidase in sepsisQ48917473
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameGermanQ188
P921main subjectsepsisQ183134
P1104number of pages12
P304page(s)479-490
P577publication date2017-07-04
P1433published inAnaesthesistQ1192168
P1476titleHeart in sepsis : Molecular mechanisms, diagnosis and therapy of septic cardiomyopathy
P478volume66

Reverse relations

cites work (P2860)
Q48124080Ablation of the Right Cardiac Vagus Nerve Reduces Acetylcholine Content without Changing the Inflammatory Response during Endotoxemia.
Q110566803COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation
Q91741502Combination era, using combined vasopressors showed benefits in treating septic shock patients: a network meta-analysis of randomized controlled trials
Q52608545Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning.
Q64947650Levosimendan as a new force in the treatment of sepsis-induced cardiomyopathy: mechanism and clinical application.
Q64235524Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes
Q88412505[Sharpen the classical view of septic cardiomyopathy]

Search more.