Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes

scientific article published on 11 March 2007

Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NM1522
P698PubMed publication ID17351626
P5875ResearchGate publication ID6454693

P2093author name stringJoseph M Backer
Marina V Backer
Francis G Blankenberg
Zoya Levashova
Kevin Claffey
Brian T Jehning
Vimalkumar Patel
P2860cites workProcessing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumorsQ24678647
Nontransgenic models of breast cancerQ24800700
The biology of VEGF and its receptorsQ27860704
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapyQ29547379
Microtumor growth initiates angiogenic sprouting with simultaneous expression of VEGF, VEGF receptor-2, and angiopoietin-2.Q31043193
Radiolabeled tracers for imaging of tumor angiogenesis and evaluation of anti-angiogenic therapiesQ31059628
Promises and pitfalls of anti-angiogenic therapy in clinical trialsQ35076995
Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesisQ35692056
The anti-angiogenic basis of metronomic chemotherapyQ35788112
Imaging angiogenesis: applications and potential for drug developmentQ36027611
Lessons from phase III clinical trials on anti-VEGF therapy for cancerQ36366446
Surface immobilization of active vascular endothelial growth factor via a cysteine-containing tag.Q40255479
In vivo tumor angiogenesis imaging with site-specific labeled (99m)Tc-HYNIC-VEGF.Q40280042
Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculatureQ40388042
Functionally active VEGF fusion proteinsQ40778735
Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: Binding, internalization, degradation, and biological effectsQ41941549
Control of radioactivity pharmacokinetics of 99mTc-HYNIC-labeled polypeptides derivatized with ternary ligand complexesQ43992762
Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endotheliaQ48600277
Imaging gastrointestinal tumours using vascular endothelial growth factor-165 (VEGF165) receptor scintigraphyQ57168246
Characterization of123I-vascular endothelial growth factor-binding sites expressed on human tumour cells: Possible implication for tumour scintigraphyQ57168258
Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent modelsQ73365474
Targeted in vivo labeling of receptors for vascular endothelial growth factor: approach to identification of ischemic tissueQ73562679
Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteinsQ77208238
Intracellular metabolic fate of radioactivity after injection of technetium-99m-labeled hydrazino nicotinamide derivatized proteinsQ77807280
A monoclonal antibody that blocks VEGF binding to VEGFR2 (KDR/Flk-1) inhibits vascular expression of Flk-1 and tumor growth in an orthotopic human breast cancer modelQ78844599
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)504-509
P577publication date2007-03-11
P1433published inNature MedicineQ1633234
P1476titleMolecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes
P478volume13

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