| P2093 | author name string | Huaxi Xu | |
| | Stuart A Lipton | |
| | Xian Zhang | |
| | Jiankun Cui | |
| | Francesca-Fang Liao | |
| | Ruishan Wang | |
| | Yun-wu Zhang | |
| | Kun Zhou | |
| P2860 | cites work | Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE | Q22010705 |
| | Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity | Q22010912 |
| | Purification and cloning of amyloid precursor protein beta-secretase from human brain | Q22010914 |
| | BACE2 functions as an alternative alpha-secretase in cells | Q24291363 |
| | The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate | Q24291471 |
| | Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients | Q24633400 |
| | BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein | Q24675964 |
| | The amyloid precursor protein: beyond amyloid | Q24680465 |
| | The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics | Q27860914 |
| | Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease | Q28140038 |
| | Interactions between Alzheimer's disease and cerebral ischemia--focus on inflammation | Q28174277 |
| | Expression and activity of beta-site amyloid precursor protein cleaving enzyme in Alzheimer's disease | Q28278732 |
| | The transcription factor Yin Yang 1 is an activator of BACE1 expression | Q28573507 |
| | HIF-1 alpha is required for solid tumor formation and embryonic vascularization. | Q28588778 |
| | Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase | Q29042710 |
| | BACE1 is the major beta-secretase for generation of Abeta peptides by neurons | Q32063781 |
| | Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation | Q33731523 |
| | The role of cerebral ischemia in Alzheimer's disease | Q33950413 |
| | BACE1 (beta-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time | Q33970104 |
| | Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma | Q34249625 |
| | Transcriptional regulation of PEN-2, a key component of the gamma-secretase complex, by CREB | Q34353695 |
| | Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor | Q34475374 |
| | Pathological and physiological functions of presenilins | Q34803524 |
| | Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression | Q35214758 |
| | HIF-1: an oxygen and metal responsive transcription factor | Q35630605 |
| | Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation | Q36105134 |
| | BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo | Q36321125 |
| | Effect of ischemic neuronal insults on amyloid precursor protein processing | Q40263442 |
| | Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels | Q40269989 |
| | Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways | Q40497465 |
| | Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1. | Q40581861 |
| | Altered processing of amyloid precursor protein in the human neuroblastoma SH-SY5Y by chronic hypoxia | Q44242849 |
| | Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease | Q44270458 |
| | BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease | Q44722202 |
| | Increased beta-secretase activity and expression in rats following transient cerebral ischemia | Q44878523 |
| | Dementia after ischemic stroke: a population-based study in Rochester, Minnesota (1960-1984) | Q45071059 |
| | Brain-specific knock-out of hypoxia-inducible factor-1alpha reduces rather than increases hypoxic-ischemic damage. | Q46448177 |
| | Accelerated accumulation of N- and C-terminal beta APP fragments and delayed recovery of microtubule-associated protein 1B expression following stroke in aged rats. | Q47750610 |
| | Stable association of presenilin derivatives and absence of presenilin interactions with APP. | Q47834589 |
| | Increased BACE1 maturation contributes to the pathogenesis of Alzheimer's disease in Down syndrome | Q48481016 |
| | Risk of dementia after stroke in a hospitalized cohort: results of a longitudinal study | Q50599916 |
| | Expression and distribution of beta amyloid precursor protein and beta amyloid peptide in reactive astrocytes after transient middle cerebral artery occlusion. | Q53243101 |
| | Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia. | Q53378635 |
| | Knockdown of hypoxia-inducible factor-1alpha by siRNA inhibits C2C12 myoblast differentiation. | Q54634455 |
| P433 | issue | 15 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hypoxia | Q105688 |
| P1104 | number of pages | 8 | |
| P304 | page(s) | 10873-10880 | |
| P577 | publication date | 2007-02-15 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation | |
| P478 | volume | 282 | |