A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement

scientific article published on 12 January 2015

A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005186908
P356DOI10.1186/SCRT540
P932PMC publication ID4417240
P698PubMed publication ID25582222
P5875ResearchGate publication ID272023167

P50authorSantiago G MiriukaQ37838835
Gustavo SevleverQ57014307
Marcela Nilda GarcíaQ109265509
P2093author name stringLeonardo Romorini
Alejandra Guberman
Claudia Solari
María Questa
Gabriel Neiman
María Elida Scassa
Carlos Luzzani
Ximena Garate
Ana Lía Errecalde
Darío Fernandez Espinosa
P2860cites workPathogen-free, plasma-poor platelet lysate and expansion of human mesenchymal stem cellsQ21245484
Derivation of multipotent mesenchymal precursors from human embryonic stem cellsQ24813785
Monitoring lymphocyte proliferation in vitro and in vivo with the intracellular fluorescent dye carboxyfluorescein diacetate succinimidyl esterQ28248444
Donor age of human platelet lysate affects proliferation and differentiation of mesenchymal stem cellsQ28729211
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissueQ29620725
Mesenchymal stem cell population derived from human pluripotent stem cells displays potent immunomodulatory and therapeutic propertiesQ33861809
Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor.Q33862395
Feeder-free growth of undifferentiated human embryonic stem cellsQ34093315
One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coatingQ34211784
Concise review: isoforms of OCT4 contribute to the confusing diversity in stem cell biologyQ34234499
Functional and differential proteomic analyses to identify platelet derived factors affecting ex vivo expansion of mesenchymal stromal cellsQ34507997
Oct-4 expression in adult human differentiated cells challenges its role as a pure stem cell marker.Q34611461
Human embryonic stem cell-derived mesoderm-like epithelium transitions to mesenchymal progenitor cells.Q34938156
Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitroQ35155712
Human embryonic stem cell-derived mesenchymal stromal cellsQ35681446
Derivation and immunological characterization of mesenchymal stromal cells from human embryonic stem cellsQ36563069
In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cellsQ37081650
Concise review: Induced pluripotent stem cell-derived mesenchymal stem cells: progress toward safe clinical products.Q37200221
Long-term in vitro expansion alters the biology of adult mesenchymal stem cellsQ37269767
Good manufacturing practices production of mesenchymal stem/stromal cells.Q37804393
Human embryonic stem cell-derived mesenchymal progenitors: an overviewQ37806175
Platelet lysate as replacement for fetal bovine serum in mesenchymal stromal cell culturesQ38165928
Novel embryoid body-based method to derive mesenchymal stem cells from human embryonic stem cellsQ38491284
Alternatives to the use of fetal bovine serum: human platelet lysates as a serum substitute in cell culture media.Q39435150
Enrichment of human ESC-derived multipotent mesenchymal stem cells with immunosuppressive and anti-inflammatory properties capable to protect against experimental inflammatory bowel disease.Q39512034
Selective isolation and differentiation of a stromal population of human embryonic stem cells with osteogenic potential.Q39651691
Analysis of OCT4 expression in an extended panel of human tumor cell lines from multiple entities and in human mesenchymal stem cells.Q39913781
Brief report--human embryonic stem cell-derived mesenchymal progenitors possess strong immunosuppressive effects toward natural killer cells as well as T lymphocytesQ39920526
Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extractQ40168400
An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.Q40450006
Long-term culture of human embryonic stem cells in feeder-free conditionsQ40595172
Induced pluripotent stem cell generation using a single lentiviral stem cell cassetteQ40721564
Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosisQ41900937
Epigenetic rejuvenation of mesenchymal stromal cells derived from induced pluripotent stem cellsQ42625062
The immunosuppressive effect of Wharton's jelly stromal cells depends on the timing of their licensing and on lymphocyte activationQ43193050
Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.Q43222889
Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applicationsQ43898390
Generation of a pool of human platelet lysate and efficient use in cell culture.Q45992553
The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapyQ47923503
Human platelet lysate allows expansion and clinical grade production of mesenchymal stromal cells from small samples of bone marrow aspirates or marrow filter washouts.Q50942078
Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells.Q51216266
Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery.Q54462820
Derivation of Clinically Compliant MSCs from CD105+, CD24− Differentiated Human ESCsQ56915439
Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric PopulationQ59713756
Immunomodulative efficacy of bone marrow-derived mesenchymal stem cells cultured in human platelet lysateQ84878975
P921main subjectmesenchymal stem cellQ1922379
P304page(s)6
P577publication date2015-01-12
P1433published inStem Cell Research & TherapyQ14390536
P1476titleA therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement
P478volume6

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cites work (P2860)
Q37352691AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival.
Q40328895Characterization of Tunneling Nanotubes in Wharton's jelly Mesenchymal Stem Cells. An Intercellular Exchange of Components between Neighboring Cells
Q64069386Comparison of human isogeneic Wharton's jelly MSCs and iPSC-derived MSCs reveals differentiation-dependent metabolic responses to IFNG stimulation
Q58702140Current Strategies to Generate Human Mesenchymal Stem Cells In Vitro
Q37432824Cyclin Kinase-independent role of p21CDKN1A in the promotion of nascent DNA elongation in unstressed cells.
Q57158902Extracellular vesicles from pluripotent stem cell-derived mesenchymal stem cells acquire a stromal modulatory proteomic pattern during differentiation
Q64080348Generation of iPSCs from Jaw Periosteal Cells Using Self-Replicating RNA
Q35974864Human Pluripotent Stem Cells and Derived Neuroprogenitors Display Differential Degrees of Susceptibility to BH3 Mimetics ABT-263, WEHI-539 and ABT-199
Q54966071Identification of the miRNAome of early mesoderm progenitor cells and cardiomyocytes derived from human pluripotent stem cells.
Q91703857Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells Are Functionally and Genetically Different From Bone Marrow-Derived Mesenchymal Stromal Cells
Q26770191Mesenchymal stem cells and immunomodulation: current status and future prospects
Q48301241Optimized human platelet lysate as novel basis for a serum-, xeno-, and additive-free corneal endothelial cell and tissue culture.
Q38999248Pluripotent Stem Cells as a Robust Source of Mesenchymal Stem Cells
Q64249676Production of Mesenchymal Stem Cells Through Stem Cell Reprogramming
Q26747501Strategies to Optimize Adult Stem Cell Therapy for Tissue Regeneration
Q26765255Use of platelet lysate for bone regeneration - are we ready for clinical translation?

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