Silencing of HIV-1 by AgoshRNA molecules

scientific article published on 29 May 2017

Silencing of HIV-1 by AgoshRNA molecules is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1085714783
P356DOI10.1038/GT.2017.44
P698PubMed publication ID28553929

P2093author name stringB Berkhout
A Harwig
E Herrera-Carrillo
P2860cites workTRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencingQ24306121
Importance of translation and nonnucleolytic ago proteins for on-target RNA interferenceQ24310424
MicroRNAs: target recognition and regulatory functionsQ24609584
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesisQ24621611
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genomeQ24802185
Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirologyQ25255128
Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2Q27661958
Asymmetry in the assembly of the RNAi enzyme complexQ27860763
Origins and Mechanisms of miRNAs and siRNAsQ27860822
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
A system for stable expression of short interfering RNAs in mammalian cellsQ27860875
Functional siRNAs and miRNAs Exhibit Strand BiasQ27861038
Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)Q28276146
Posttranscriptional regulation of microRNA biogenesis in animalsQ28282519
A dicer-independent miRNA biogenesis pathway that requires Ago catalysisQ28508177
Rational siRNA design for RNA interferenceQ29614450
Perspective: machines for RNAiQ29616378
Sequence features associated with microRNA strand selection in humans and fliesQ33500345
Minimal-length short hairpin RNAs: the relationship of structure and RNAi activityQ33572896
The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation siteQ33580358
Self-inactivating lentivirus vector for safe and efficient in vivo gene deliveryQ33786060
A Rev-independent human immunodeficiency virus type 1 (HIV-1)-based vector that exploits a codon-optimized HIV-1 gag-pol geneQ33804963
RNAi-inducing lentiviral vectors for anti-HIV-1 gene therapyQ34172916
Absence of DICER in monocytes and its regulation by HIV-1.Q34186317
Role of Dicer in posttranscriptional RNA silencingQ34749330
Comparison of siRNA-induced off-target RNA and protein effectsQ35641220
SHAPE-directed discovery of potent shRNA inhibitors of HIV-1.Q35876214
Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencingQ36305658
microRNAs associated with the different human Argonaute proteinsQ36341483
Human immunodeficiency virus type 1 escape is restricted when conserved genome sequences are targeted by RNA interferenceQ36483991
Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1Q37256335
Toward a durable anti-HIV gene therapy based on RNA interferenceQ37606516
The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiationQ37648485
Towards improved shRNA and miRNA reagents as inhibitors of HIV-1 replicationQ38210324
Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairsQ38902799
Dicer-independent processing of short hairpin RNAsQ39200306
A competitive cell growth assay for the detection of subtle effects of gene transduction on cell proliferation.Q39437932
Off-target and a portion of target-specific siRNA mediated mRNA degradation is Ago2 'Slicer' independent and can be mediated by Ago1.Q39797171
A systematic analysis of the effect of target RNA structure on RNA interferenceQ40118209
Pol III Promoters to Express Small RNAs: Delineation of Transcription InitiationQ40136826
Silencing of HIV-1 with RNA interference: a multiple shRNA approachQ40234514
The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interferenceQ40237024
Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1.Q40284337
Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibitionQ40589914
Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and TrimmingQ40739587
Deletion of the GPG motif in the HIV type 1 V3 loop does not abrogate infection in all cellsQ40907102
Titers of lentiviral vectors encoding shRNAs and miRNAs are reduced by different mechanisms that require distinct repair strategiesQ41068705
Characterization of cells of the myeloid-monocytic lineage (ML-1, HL-60, THP-1, U-937) chronically infected with the human immunodeficiency virus-1.Q41585291
Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-1LAI, HIV-1MAL, and HIV-1ELI.Q41655443
Human immunodeficiency virus infection in cells of myeloid-monocytic lineageQ41702984
Differentiating agents facilitate infection of myeloid leukemia cell lines by monocytotropic HIV-1 strainsQ41714762
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activityQ41845562
Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effectsQ41853149
Molecular Properties, Functional Mechanisms, and Applications of Sliced siRNA.Q42110364
Poly(A)-specific ribonuclease mediates 3'-end trimming of Argonaute2-cleaved precursor microRNAsQ42136359
Designing Ago2-specific siRNA/shRNA to Avoid Competition with Endogenous miRNAsQ42139003
Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activityQ42205586
Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytesQ43954074
Induction of an interferon response by RNAi vectors in mammalian cellsQ58235166
P433issue8
P304page(s)453-461
P577publication date2017-05-29
P1433published inGene TherapyQ15763095
P1476titleSilencing of HIV-1 by AgoshRNA molecules
P478volume24