Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response

scientific article published on 24 September 2014

Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01923-14
P932PMC publication ID4248989
P698PubMed publication ID25253344
P5875ResearchGate publication ID266152018

P50authorXavier CarnecQ29459058
Marion RussierQ57418055
Sylvain BaizeQ62808029
Stéphanie ReynardQ63922484
P2093author name stringAlexandra Fizet
P2860cites workCD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cellsQ24528149
Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon InductionQ27485881
Isolation of an arenavirus closely related to Lassa virus from Mastomys natalensis in south-east AfricaQ27485975
Cap binding and immune evasion revealed by Lassa nucleoprotein structureQ27665958
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppressionQ27666703
Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune SuppressionQ27677547
Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa virusesQ33964796
Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cellsQ33976118
Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virusQ34999702
Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virusQ35140402
Plasmacytoid dendritic cells are productively infected and activated through TLR-7 early after arenavirus infectionQ36041511
Pathogenic Old World arenaviruses inhibit TLR2/Mal-dependent proinflammatory cytokines in vitroQ36155495
Cleavage of the Junin virus nucleoprotein serves a decoy function to inhibit the induction of apoptosis during infectionQ36506841
Review of cases of nosocomial Lassa fever in Nigeria: the high price of poor medical practiceQ36905074
Production of CXC and CC chemokines by human antigen-presenting cells in response to Lassa virus or closely related immunogenic viruses, and in cynomolgus monkeys with lassa feverQ37464889
Human macrophages, but not dendritic cells, are activated and produce alpha/beta interferons in response to Mopeia virus infectionQ37511565
Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophagesQ38959283
An arenavirus RING (zinc-binding) protein binds the oncoprotein promyelocyte leukemia protein (PML) and relocates PML nuclear bodies to the cytoplasm.Q39577454
Arenavirus nucleoproteins prevent activation of nuclear factor kappa B.Q40285838
Role of interferons in the control of Lassa virus replication in human dendritic cells and macrophages.Q40481084
A prospective study of the epidemiology and ecology of Lassa feverQ40798878
Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virusQ41847342
Differential inhibition of type I interferon induction by arenavirus nucleoproteinsQ41937252
Protection of rhesus monkeys from Lassa virus by immunisation with closely related ArenavirusQ45894483
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectLassa virusQ1806636
P304page(s)13923-13927
P577publication date2014-09-24
P1433published inJournal of VirologyQ1251128
P1476titleExonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response
P478volume88

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cites work (P2860)
Q52625005A vaccine platform against arenaviruses based on a recombinant hyper-attenuated Mopeia virus expressing heterologous glycoproteins.
Q66679118Comparative Structure and Function Analysis of the RIG-I-Like Receptors: RIG-I and MDA5
Q40259618Development of Recombinant Arenavirus-Based Vaccines.
Q35487706Development of live-attenuated arenavirus vaccines based on codon deoptimization
Q64097889Hemorrhagic Fever-Causing Arenaviruses: Lethal Pathogens and Potent Immune Suppressors
Q36753696Influence of RNA Binding on the Structure and Dynamics of the Lassa Virus Nucleoprotein
Q59351260Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells
Q39337289Molecular pathogenesis of viral hemorrhagic fever.
Q39394740New World Arenavirus Biology.
Q63916866Non-Pathogenic Mopeia Virus Induces More Robust Activation of Plasmacytoid Dendritic Cells than Lassa Virus
Q26770021Nucleocapsid proteins: roles beyond viral RNA packaging
Q26742028Reporter-Expressing, Replicating-Competent Recombinant Arenaviruses
Q37543755Reverse Genetics Approaches to Control Arenavirus.
Q56913187The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model
Q40189592The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses
Q28392078Viral evasion of intracellular DNA and RNA sensing
Q63741077Virus⁻Host Interactions Involved in Lassa Virus Entry and Genome Replication
Q59354952Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells
Q40112265What can pestiviral endonucleases teach us about innate immunotolerance?

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