Significance of various enzymes in the control of mutagenic and carcinogenic metabolites derived from aromatic structures

scientific article published on January 1984

Significance of various enzymes in the control of mutagenic and carcinogenic metabolites derived from aromatic structures is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1177/019262338401200414
P698PubMed publication ID6398501
P5875ResearchGate publication ID16796799

P2093author name stringF Oesch
P2860cites workGenetic expression of aryl hydrocarbon hydroxylase activity in the mouseQ33984668
Mammalian Epoxide Hydrases: Inducible Enzymes Catalysing the Inactivation of Carcinogenic and Cytotoxic Metabolites Derived from Aromatic and Olefinic CompoundsQ34213703
Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxidesQ35034447
Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cellsQ35986055
Enzymic reduction of aromatic hydrocarbon epoxides by the microsomal fraction of rat liverQ40335754
Mutagenicity of isomeric diol-epoxides of benzo[a]pyrene and benz[a]anthracene in S. typhimurium TA98 and TA100 and in V79 Chinese hamster cellsQ40813052
Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyreneQ40855580
Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localizationQ40855586
Purification and characterization of a new cytosolic glutathione S-transferase (glutathione S-transferase X) from rat liverQ42865655
Arene oxides: a new aspect of drug metabolismQ47853644
Inactivation of a diol epoxide by dihydrodiol dehydrogenase but not by two epoxide hydrolasesQ50214265
Metabolic activations of polycyclic hydrocarbons. Structure-activity relationships.Q53588151
Phylogenetic distribution of epoxide hydratase in different vertebrate species, strains and tissues measured using three substratesQ53982480
Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cellsQ59062603
Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxideQ59062693
Reduction of benzo(a)pyrene mutagenicity by dihydrodiol dehydrogenaseQ59089154
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)391-396
P577publication date1984-01-01
P1433published inToxicologic PathologyQ7830407
P1476titleSignificance of various enzymes in the control of mutagenic and carcinogenic metabolites derived from aromatic structures
P478volume12

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