The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions

scientific article published on 14 November 2006

The promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00510.2006
P698PubMed publication ID17106062
P5875ResearchGate publication ID6691797

P50authorChristopher B NewgardQ87867408
P2093author name stringDonald K Scott
Danhong Lu
Pili Zhang
John W Haycock
Alex J Lange
Chris Doumen
Kim B Pedersen
Marcel Charbonnet
P2860cites workThe role of HNF1alpha, HNF3gamma, and cyclic AMP in glucose-6-phosphatase gene activationQ24336697
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding proteinQ24555088
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcriptionQ24561983
Triggering and amplifying pathways of regulation of insulin secretion by glucoseQ27863677
Hepatocyte nuclear factor-1 acts as an accessory factor to enhance the inhibitory action of insulin on mouse glucose-6-phosphatase gene transcriptionQ28513198
c-Myc is required for the glucose-mediated induction of metabolic enzyme genesQ28568372
Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal ratsQ28572235
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liverQ28583240
Comparison of DNA sequences with protein sequences.Q30471433
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemiaQ30794086
Glucose regulation of the acetyl-CoA carboxylase promoter PI in rat hepatocytesQ30988773
A dominant-negative inhibitor of CREB reveals that it is a general mediator of stimulus-dependent transcription of c-fosQ33771493
Direct role of ChREBP.Mlx in regulating hepatic glucose-responsive genesQ34387089
Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.Q34461739
Isolation of a cDNA for the catalytic subunit of rat liver glucose-6-phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP.Q36751840
Regulation of rat liver glucose-6-phosphatase gene expression in different nutritional and hormonal states: gene structure and 5'-flanking sequenceQ36826589
Glucose-6-phosphatase activity in islets from ob/ob and lean mice and the effect of dexamethasoneQ38296000
Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genesQ38345565
Intestinal glucose-dependent expression of glucose-6-phosphatase: involvement of the aryl receptor nuclear translocator transcription factor.Q40446912
A distal region involving hepatocyte nuclear factor 4alpha and CAAT/enhancer binding protein markedly potentiates the protein kinase A stimulation of the glucose-6-phosphatase promoter.Q40511864
Quantification and glucocorticoid regulation of glucocorticoid receptor transcripts in two human leukemic cell linesQ40634573
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretionQ40871524
Differential role of hepatocyte nuclear factor-1 in the regulation of glucose-6-phosphatase catalytic subunit gene transcription by cAMP in liver- and kidney-derived cell linesQ40886678
Glucose induces glucose 6-phosphatase hydrolytic subunit gene transcription in an insulinoma cell line (INS-1).Q40976117
Adenovirus-mediated expression of the catalytic subunit of glucose-6-phosphatase in INS-1 cells. Effects on glucose cycling, glucose usage, and insulin secretionQ41089209
Stimulation of glucose-6-phosphatase gene expression by glucose and fructose-2,6-bisphosphateQ41110631
Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagonQ41817493
A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulinQ42437256
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequenceQ42477315
ChREBP rather than USF2 regulates glucose stimulation of endogenous L-pyruvate kinase expression in insulin-secreting cellsQ42522956
Regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Use of the stable transfection approach to locate an insulin responsive sequenceQ42810951
Regulation of the glucose-6-phosphatase gene by glucose occurs by transcriptional and post-transcriptional mechanisms. Differential effect of glucose and xylitolQ43510347
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcriptionQ43560420
Marked disparity between age‐related changes in dopamine and other presynaptic dopaminergic markers in human striatumQ44612066
A modest glucokinase overexpression in the liver promotes fed expression levels of glycolytic and lipogenic enzyme genes in the fasted state without altering SREBP-1c expressionQ44692685
ChREBP*Mlx is the principal mediator of glucose-induced gene expression in the liverQ50336015
Glucose regulates in vivo glucose-6-phosphatase gene expression in the liver of diabetic rats.Q51581844
A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.Q53441453
P433issue3
P304page(s)E788-801
P577publication date2006-11-14
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleThe promoter for the gene encoding the catalytic subunit of rat glucose-6-phosphatase contains two distinct glucose-responsive regions
P478volume292

Reverse relations

cites work (P2860)
Q34117649A retrospective review of the roles of multifunctional glucose-6-phosphatase in blood glucose homeostasis: Genesis of the tuning/retuning hypothesis
Q90118074Carbohydrate response element binding protein (ChREBP) correlates with colon cancer progression and contributes to cell proliferation
Q58600361ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners
Q35903586ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β-Cell Line
Q36109313ChREBP mediates glucose-stimulated pancreatic β-cell proliferation
Q39221068Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis
Q39913741Expression and function of alphabeta1 integrins in pancretic beta (INS-1) cells
Q54538841Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes.
Q36128130Functional Analysis of Mouse G6pc1 Mutations Using a Novel In Situ Assay for Glucose-6-Phosphatase Activity and the Effect of Mutations in Conserved Human G6PC1/G6PC2 Amino Acids on G6PC2 Protein Expression
Q35603371Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin
Q39233300Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter
Q28256072Glucose-6-phosphatase catalytic subunit gene family
Q46716195Hepatic glucose sensing via the CREB coactivator CRTC2.
Q47270010Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice.
Q36311553Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation
Q33699177Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose
Q35796929O-GlcNAcylation increases ChREBP protein content and transcriptional activity in the liver
Q58795278Recent insights into the role of ChREBP in intestinal fructose absorption and metabolism
Q41517260Sequence variation between the mouse and human glucose-6-phosphatase catalytic subunit gene promoters results in differential activation by peroxisome proliferator activated receptor gamma coactivator-1alpha
Q35543390Species-specific inhibitor sensitivity of angiotensin-converting enzyme 2 (ACE2) and its implication for ACE2 activity assays
Q27316318The Caenorhabditis elegans Myc-Mondo/Mad complexes integrate diverse longevity signals
Q36748118The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells
Q39152848The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism
Q39216040The regulation and role of carbohydrate response element binding protein in metabolic homeostasis and disease.
Q28299919The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs
Q33874328c-Myc is required for the CHREBP-dependent activation of glucose-responsive genes

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