T cell recognition of antigen in vivo: role of the H-2 complex

scientific article published on August 1980

T cell recognition of antigen in vivo: role of the H-2 complex is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/BF02053976
P698PubMed publication ID6455762

P2093author name stringJ Sprent
R Korngold
K Molnar-Kimber
P2860cites workFunctional Activity of T Cells which Differentiate from Nude Mouse Precursors in a Congenic or Allogeneic Thymus GraftQ33707583
Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assayQ33903838
Interaction Between Antigen-Presenting Cells and Primed T Lymphocytes. An Assessment of Ir Gene Expression in the Antigen-Presenting CellQ34154332
The Role of I Region Gene Products in Macrophage - T Lymphocyte InteractionQ34154351
Influence of the Major Histocompatibility Complex on T-Cell ActivationQ34205764
In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 typeQ34321361
Role of major histocompatibility complex gene products in delayed-type hypersensitivityQ35012164
Nature of the antigenic complex recognized by T lymphocytes: specific sensitization by antigens associated with allogeneic macrophagesQ35028017
The somatic generation of immune recognitionQ35673404
Histocompatibility-linked immune response gene function in guinea pigs. Specific inhibition of antigen-induced lymphocyte proliferation by alloantiseraQ36272091
Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugatesQ36272251
Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytesQ36272607
Function of macrophages in antigen recognition by guinea pig T lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune responseQ36272651
Effect of recent antigen priming on adoptive immune responses. II. Specific unresponsiveness of circulating lymphocytes from mice primed with heterologous erythrocytesQ36272849
Independent populations of primed F1 guinea pig T lymphocytes respond to antigen-pulsed parental peritoneal exudate cellsQ36335481
Antigen presentation in the murine T-lymphocyte proliferative response. I. Requirement for genetic identity at the major histocompatibility complexQ36335803
H-2 effects on cell-cell interactions in the response to single non-H-2 alloantigens. II. H-2 D region control of H-7.1-specific stimulator function in mixed lymphocyte culture and susceptibility to lysis by H-7.1- specific cytotoxic cellsQ36336155
H-2 effects on cell-cell interactions in the response to single non-H-2 alloantigens. I. Donor H-2D region control of H-7.1-immunogenicity and lack of restriction in vivoQ36336226
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and ResponsivenessQ39576364
The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expressionQ39634636
Influence of Thymus Genotype on Acquisition of Responsiveness in Delayed-type HypersensitivityQ39646886
The role of H-2-linked genes in helper T-cell function. VI. Expression of Ir genes by helper T cellsQ39655894
Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strainQ39736459
Techniques for Separation and Selection of Antigen Specific LymphocytesQ39785486
T cell proliferation in the mixed lymphocyte culture does not necessarily result in the generation of cytotoxic T effector cellsQ39788638
T Lymphocyte Stimulation by Hapten-Conjugated Macrophages. A Model System for the Study of Immunocompetent Cell InteractionsQ39802469
T lymphocyte responses to Mls locus antigens involve recognition of H-2 I region gene productsQ39816014
Nature of the antigenic complex recognized by T lymphocytes. V. Genetic predisposition of independent F1 T cell subpopulations responsive to antigen-pulsed parental macrophagesQ39841534
Functions of macrophages in antibody responses in vitroQ39869384
Immunogenetic and biological aspects of in vitro lymphocyte allotransformation (MLR) in the mouseQ39869822
Allotype-specific analysis of anti-(TYR,GLU)-ALA-LYS antibodies produced by Ir-1A high and low responder chimeric miceQ36337172
The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T helpQ36339973
On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?Q36340069
Cytotoxic T cells recognize male antigen and H-2 as distinct entitiesQ36340116
Cellular and genetic control of antibody responses in vitro. III. Immune response gene regulation of accessory cell functionQ36340360
The immune response of allophenic mice to 2,4-dinitrophenyl (DNP)-bovine gamma globulin. I. Allotype analysis of anti-DNP antibodyQ36340433
The role of H-2 linked genes in helper T-cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper T cells each specific for antigen and one set of parental H-2 productsQ36340749
Gene complementation in the T-lymphocyte proliferative response to poly (Glu55Lys36Phe9)n. A demonstration that both immune response gene products must be expressed in the same antigen-presenting cellQ36341092
Nature of T-cell macrophage interaction in helper-cell induction in vitro. II. Two stages of T-helper-cell differentiation analyzed in irradiation and allophenic chimerasQ36341283
Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cellsQ36341427
The in vitro generation and sustained culture of nude mouse cytolytic T-lymphocytesQ36341555
Adaptive differentiation of murine lymphocytes. II. The thymic microenvironment does not restrict the cooperative partner cell preference of helper T cells differentiating in F1 leads to F1 thymic chimerasQ36341593
T-cell populations specifically depleted of alloreactive potential cannot be induced to lyse H-2-different virus-infected target cellsQ36341706
H-2 antigens of the thymus determinelymphocyte specificityQ36341908
The histocompatibility restrictions on macrophage T-helper cell interaction determine the histocompatibility restrictions on T-helper cell B-cell interactionQ36342042
The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigensQ36342063
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrowQ36342244
T cells recognize minor histocompatibility antigens on H-2 allogeneic cellsQ36342916
Delayed-type hypersensitivity to allogeneic cells in mice. III. Sensitivity to cell-surface antigens coded by the major histocompatibility complex and by other genesQ36342929
The specific binding of Listeria monocytogenes-immune T lymphocytes to macrophages. I. Quantitation and role of H-2 gene productsQ36343002
Distinct Ir genes for helper and killer cells in the cytotoxic response to H-Y antigenQ36343026
Functional analysis of T cells expressing Ia antigens. I. Demonstration of helper T-cell heterogeneityQ36343076
Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expressionQ36343082
Suppression of T cells specific for the nonthymic parental H-2 haplotype in thymus-grafted chimerasQ36343268
Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinantsQ36343343
Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complexQ36358161
Collaboration of allogeneic T and B lymphocytes in the primary antibody response to sheep erythrocytes in vitroQ36358453
The allogeneic bisection of carrier-specific enhancement of monoclonal B-cell responsesQ36358547
In vitro cell-mediated immune responses to the male specific(H-Y) antigen in miceQ36358603
The major histocompatibility complex determines susceptibility to cytotoxic T cells directed against minor histocompatibility antigensQ36358831
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinantsQ36359104
T-lymphocyte-enriched murine peritoneal exudate cells. II. Genetic control of antigen-induced T-lymphocyte proliferationQ36359167
T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cellsQ36359717
Cell-mediated immunity and the major histocompatibility complexQ39877107
Cross-reactivity exists between Mlsa and Mlsd lymphocyte-activating determinants as demonstrated by the negative clonal selection of responder cells in a mixed lymphocyte reactionQ39891545
Genetics and immunology of sex-linked antigensQ39907579
Thymus and antigen-reactive cellsQ40005247
Immunologic complementation between thymus and marrow cells--a model for the two-cell theory of immunocompetence.Q40005259
H–2 restriction and non-restriction of T-cell-mediated cytotoxicity against mouse mammary tumour targetsQ40205661
Early cellular events in a systemic graft-vs.-host reaction. II. Autoradiographic estimates of the frequency of donor lymphocytes which respond to each Ag-B-determined antigenic complexQ40309613
The role of Langerhans cells in allergic contact hypersensitivity. A review of findings in man and guinea pigsQ40525519
Lymphocytes as Models for the Study of Mammalian Cellular DifferentiationQ40643388
In vitro induction of tumor-specific immunity. III. Lack of requirement for H-2 compatibility in lysis of tumor targets by T cells activated in vitro to oncofetal and plasmacytoma antigensQ40643617
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigensQ40649920
In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cellsQ40658124
Generation of T helper cells in vitro. IV. F1 T helper cells primed with antigen-pulsed parental macrophages are genetically restricted in their antigen-specific helper activityQ40666442
T cells specific for hapten-modified self are precommitted for self major histocompatibility complex antigens before encounter with the haptenQ40676778
Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. I. Failure to collaborate with B cells of the opposite parental strain not associated with active suppressionQ40676798
Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of thQ40676806
Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complexQ40685944
Idiotype-specific T helper cells are required to induce idiotype-positive B memory cells to secrete antibodyQ40690288
Role of the H-2 complex in induction of T helper cells in vivo. I. Antigen-specific selection of donor T cells to sheep erythrocytes in irradiated mice dependent upon sharing of H-2 determinants between donor and hostQ40690826
Two subgroups of T helper cells in F1 hybrid mice revealed by negative selection to heterologous erythrocytes in vivoQ40693510
Nature of T cell-macrophage interaction in helper cell inductionin vitro I. Evidence for genetic restriction of T cell-macrophage interactions prior to T cell primingQ40695350
Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complexQ40701083
T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cellsQ40701106
Studies on the generation and expression of H-2-controlled T helper function in chimeric mice: Evidence for two levels of H-2 restrictionQ40728646
Ia antigen expression on human epidermal Langerhans cellsQ40792234
Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cellsQ41367783
Selection of cytotoxic T-cell precursors specific for minor histocompatibility determinants. I. Negative selection across H-2 barriers induced with disrupted cells but not with glutaraldehyde-treated cells: evidence for antigen processingQ41789078
On the role of the H-2 histocompatibility complex in determining the specificity of cytotoxic effector cells sensitized against syngeneic trinitrophenyl-modified targetsQ41816941
The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigensQ41833807
Antibody response of C3H in equilibrium (CKB X CWB)F1 tetraparental mice to poly-L(Tyr,Glu)-poly-D,L-Ala-poly-L-Lys immunizationQ41879326
Minor H antigens introduced on H-2 different stimulating cells cross-react at the cytotoxic T cell level during in vivo primingQ41895196
The specific selection of recirculating lymphocytes by antigen in normal and preimmunized ratsQ41898561
Helper function of T cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated F1 hybrid recipients. I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivoQ42118420
Effect of recent antigen priming on adoptive immune responses. IV. Antigen-induced selective recruitment of recirculating lymphocytes to the spleen demonstrable with a microculture systemQ42137715
In vivo requirement for a radiation-resistant cells in the immune response to sheep erythrocytesQ42206069
Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complexQ42259756
Allogeneic carrier-specific enhancement of hapten-specific secondary B-cell responsesQ42941082
Antigen-induced selective recruitment of circulating lymphocytesQ44125070
Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cellsQ44354770
Helper T cells recognise antigen and macrophage surface components simultaneously.Q52241720
H-2 dependence of co-operation between T and B cells in vivo.Q53765275
Cell interactions in the immune response in vitro. I. Metabolic activities of T cells in a collaborative antibody response.Q54586871
The cross-linking of proteins with glutaraldehyde and its use for the preparation of immunoadsorbents.Q54645824
The function and interrelationships of T-cell receptors, Ir genes and other histocompatibility gene productsQ66875394
Adaptive differentiation of murine lymphocytes. I. Both T and B lymphocytes differentiating in F1 transplanted to parental chimeras manifest preferential cooperative activity for partner lymphocytes derived from the same parental type correspondingQ66877735
Cytotoxic T lymphocytes recognise allogeneic tolerated TNP-conjugated cellsQ66884284
Five types of lymphocytes (lg− θ−, lg− θ+ weak, lg− θ+strong, lg+ θ− and lg+ θ+) characterized by double immunofluorescence and electrophoretic mobility Organ distribution in normal and nude miceQ66888042
Macrophage Ia antigens. I. macrophage populations differ in their expression of Ia antigensQ67253568
Can tolerant allogeneic cells restore nude mice?Q67353188
Specific unresponsiveness of recirculating lymphocytes ater exposure to histocompatibility antigen in F 1 hybrid ratsQ68760146
The H-2D and H-2K regions of the major histocompatibility system and the M locus of the mouse investigated by parabiosisQ70007455
Regulation by the H-2 gene complex of macrophage-lymphoid cell interactions in secondary antibody responses in vitroQ36359776
The effect of allogeneic presensitization on H-Y graft survival and in vitro cell-mediated responses to H-y antigenQ36359795
Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigensQ36359978
T-cell-dependent B-cell stimulation is H-2 restricted and antigen dependent only at the resting B-cell levelQ36360899
H-2 gene complex restricts transfer of delayed-type hypersensitivity in miceQ37466327
Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregionQ37586710
Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder miceQ37586973
The influence of thymus on the development of MHC restrictions exhibited by T-helper cellsQ38595843
Induction of H-2-restricted cytotoxic T cells: in vivo induction has the appearance of being unrestrictedQ39164207
Tolerance to histocompatibility determinants in tetraparental bone marrow chimerasQ39314527
Two genes in the major histocompatibility complex control immune responseQ39338895
The role of macrophages in the generation of T-helper cells. I. The requirement for macrophages in helper cell induction and characteristics of the macrophage-T cell interactionQ39353253
Role of the Murine Major Histocompatibility Complex in the Specificity of in vitro T-Cell-Mediated Lympholysis Against Chemically-Modified Autologous LymphocytesQ39383683
T cell function in bone marrow chimeras: absence of host-reactive T cells and cooperation of helper T cells across allogeneic barriersQ39383698
Specificity of Virus-Immune Effector T Cells for H-2K or H-2D Compatible Interactions: Implications for H-Antigen DiversityQ39383715
Two Different VH Gene Products Make Up the T-Cell ReceptorsQ39414474
On the Possibility of Multiple T-cell ReceptorsQ39448568
Responsiveness to HY Antigen Ir Gene Complementation and Target Cell SpecificityQ39449141
The role of Ia antigens in T cell activationQ39449149
Genetic control of the immune response to Thy-1 antigensQ39475222
The immune response genes of the major histocompatibility complexQ39475236
A dual recognition model for cytotoxic T cells based on thymic selection of precursors with low affinity for Self H-2 antigensQ39489681
A hypothesis to relate the specificity of T lymphocytes and the activity of I region-specific Ir genes in macrophages and B lymphocytesQ39491805
Apparent lack of H-2 restriction of allograft rejectionQ39506429
Expression and Function of Idiotypes on LymphocytesQ39509367
A subpopulation of adherent accessory cells bearing both I-A and I-E or C subregion antigens is required for antigen-specific murine T lymphocyte proliferationQ39515162
Role of H-2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo1Q39526566
Alloreactivity, the Development of the T Cell Repertoire and the Understanding of T Cell FunctionQ39526572
The Influence of the Major Histocompatibility Complex on the Function of T-Helper Cells in Antibody FormationQ39526580
Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H-2-Restriction-Specificity and in H-2 Linked Ir Gene ControlQ39526586
The Influence of Thymus H-2 Antigens on the Specificity of Maturing Killer and Helper CellsQ39526592
Cell types required for H-2-restricted cytotoxic responses generated by trinitrobenzene sulfonate-modified syngeneic cells or trinitrophenyl-conjugated proteinsQ39548557
Determinant Selection and Macrophage Function in Genetic Control of the Immune ResponseQ39558237
In vitro evidence from anti-hapten antibody responses for T helper and suppressor cells directed against major histocompatibility antigens in the mouse. Participation of I region determinants in the induction of T helper cellsQ39572550
P433issue2
P304page(s)213-245
P577publication date1980-08-01
P1433published inSeminars in ImmunopathologyQ15724576
P1476titleT cell recognition of antigen in vivo: role of the H-2 complex
P478volume3

Reverse relations

cites work (P2860)
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