Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells.

scientific article published on 3 October 2006

Heparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M513414200
P698PubMed publication ID17020882

P50authorMichael P. O'ConnellQ79188035
P2093author name stringDavid L Glaser
Eileen M Shore
Frederick S Kaplan
Paul C Billings
Xiangyang Jiao
P2860cites workMutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndromeQ24320198
Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradientsQ28204970
Hereditary multiple exostoses and heparan sulfate polymerizationQ28213553
Cell-surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordinQ28512603
Heparan sulfate is required for bone morphogenetic protein-7 signalingQ28570924
A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblastsQ28588836
Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesisQ28589851
Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functionsQ28609232
Functions of cell surface heparan sulfate proteoglycansQ29618521
Action range of BMP is defined by its N-terminal basic amino acid coreQ34113614
Cell surface heparan sulfate proteoglycans and lipoprotein metabolismQ34158646
Genetic dissection of proteoglycan function in Drosophila and C. elegansQ34211782
Different heparan sulfate proteoglycans serve as cellular receptors for human papillomavirusesQ34227402
Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist NogginQ34279840
Heparan sulfate proteoglycan as a plasma membrane carrierQ35084374
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineageQ36235105
Low doses and high doses of heparin have different effects on osteoblast-like Saos-2 cells in vitroQ40575533
Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressivaQ41174010
Human bone morphogenetic protein 2 contains a heparin-binding site which modifies its biological activityQ41211589
Internalization and stepwise degradation of heparan sulfate proteoglycans in rat hepatocytesQ43832500
Distinct endocytic pathways regulate TGF-β receptor signalling and turnoverQ44419411
Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycansQ47070505
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activityQ47070543
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signallingQ47070638
Spatial regulation of Wingless morphogen distribution and signaling by Dally-like proteinQ47071991
Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins.Q51837891
Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.Q52086756
Developmental Regulation of Neural Response to FGF-1 and FGF-2 by Heparan Sulfate ProteoglycanQ52225676
Endocytosis and signaling: a relationship under development.Q53139509
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectheparan sulfate proteoglycansQ66589633
P304page(s)1080-1086
P577publication date2006-10-03
P1433published inJournal of Biological ChemistryQ867727
P1476titleHeparan sulfate proteoglycans (HSPGs) modulate BMP2 osteogenic bioactivity in C2C12 cells
P478volume282