IL-15 protects intestinal epithelial cells

scientific article published on October 2006

IL-15 protects intestinal epithelial cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.200535173
P698PubMed publication ID16981178

P50authorJürgen SchölmerichQ1717698
Silvia Bulfone-PausQ7516970
Martin HausmannQ73799368
Hans H HerfarthQ88930936
Silvia KellermeierQ114734461
Florian ObermeierQ114734462
Nadja DungerQ114734463
Gerhard RoglerQ64750687
P2093author name stringUlrike G Strauch
Jürgen Bock
Werner Falk
Michael Stoeck
Stefan Kiessling
Erwin Duitman
P2860cites workDefects in mucosal immunity leading to Crohn's diseaseQ22242645
Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genesQ24312972
Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptorQ24313035
Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptorQ24323032
Role of interleukin 15 and interleukin 18 in inflammatory responseQ24675082
Interleukin 15 is a growth factor for human thymocytes with preferential effect on CD8(+)cellsQ73869484
Interleukin-15 preferentially promotes the growth of intestinal intraepithelial lymphocytes bearing gamma delta T cell receptor in miceQ73933718
CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated miceQ74456268
Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in ratsQ74522611
Interleukin-15 and its role in chronic inflammatory diseasesQ77158084
The structure and function of gamma c-dependent cytokines and receptors: regulation of T lymphocyte development and homeostasisQ77714086
Interferon-gamma (IFN-gamma)- and tumour necrosis factor (TNF)-induced nitric oxide as toxic effector molecule in chronic dextran sulphate sodium (DSS)-induced colitis in miceQ77774791
Intestinal epithelial cells both express and respond to interleukin 15Q28575535
Association between innate response to gliadin and activation of pathogenic T cells in coeliac diseaseQ34213073
Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cellsQ34299001
IL-15, a survival factor for kidney epithelial cells, counteracts apoptosis and inflammation during nephritisQ34790437
Interleukin-15 and the regulation of lymphoid homeostasis.Q34996773
Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.Q35760432
Intestinal epithelial cell regulation of mucosal inflammationQ35794610
Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptorQ36363861
Antibodies to interleukin 12 abrogate established experimental colitis in miceQ36365464
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's diseaseQ36370178
T helper 1 and T helper 2 cells are pathogenic in an antigen-specific model of colitisQ36376495
T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cellsQ36400646
CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammationQ38321426
Interleukin-2 receptor beta subunit-dependent and -independent regulation of intestinal epithelial tight junctionsQ40790831
Increased expression of IL-15 in the synovium of patients with rheumatoid arthritis compared with patients with Yersinia-induced arthritis and osteoarthritisQ41488596
IL-15 and IL-2: a matter of life and death for T cells in vivoQ42639989
Role of interleukin 15 in colitis induced by dextran sulphate sodium in miceQ42844890
Human intestinal epithelial cells secrete interleukin-1 receptor antagonist and interleukin-8 but not interleukin-1 or interleukin-6.Q43086543
The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo.Q43648190
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in miceQ44753508
Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Ralpha.Q45730303
CD45RChighCD4+ intestinal mucosal lymphocytes infiltrating in the inflamed colonic mucosa of a novel rat colitis model induced by TNB immunizationQ47769043
A role for IL-15 in rheumatoid arthritis?Q47982964
Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell developmentQ47997005
Interleukin 15 activity in the rectal mucosa of inflammatory bowel disease.Q48019542
IL-15 induces type 1 and type 2 CD4+ and CD8+ T cells proliferation but is unable to drive cytokine production in the absence of TCR activation or IL-12 / IL-4 stimulation in vitro.Q52014852
Interleukin-15 protects from lethal apoptosis in vivo.Q52998398
Differential regulation of human T lymphoblast functions by IL-2 and IL-15.Q52999502
Interleukin 15: a proinflammatory role in rheumatoid arthritis synovitisQ57232104
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritisQ57232110
The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritisQ57232112
Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: correlation with disease activityQ60017516
Intragraft IL-15 transcripts are increased in human renal allograft rejectionQ71469425
Unconventional T-cell activation by IL-15 in rheumatoid arthritisQ73034244
Colonic expression and synthesis of interleukin 13 and interleukin 15 in inflammatory bowel diseaseQ73053448
IL-15 and IL-15 receptor selectively regulate differentiation of common mucosal immune system-independent B-1 cells for IgA responsesQ73086186
Interleukin-15 is a potent survival factor in the prevention of spontaneous but not CD95-induced apoptosis in CD4 and CD8 T lymphocytes of HIV-infected individuals. Correlation with its ability to increase BCL-2 expressionQ73170785
Differential role for IL-2 and IL-15 in the inhibition of apoptosis in short-term activated human lymphocytesQ73454842
CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitisQ73475899
Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitisQ73513291
IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine productionQ73567308
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2691-2699
P577publication date2006-10-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleIL-15 protects intestinal epithelial cells
P478volume36

Reverse relations

cites work (P2860)
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