Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences

scientific article published on 22 July 2011

Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00395-011-0208-6
P932PMC publication ID3640464
P698PubMed publication ID21785893
P5875ResearchGate publication ID51518171

P50authorRoberto BolliQ56166630
P2093author name stringNing Chen
Wei Tan
Li Luo
Buddhadeb Dawn
Xiaoping Zhu
Qianhong Li
Yiru Guo
Qinghui Ou
Wen-Jian Wu
Fangping Yuan
Gregory N Hunt
P2860cites workGene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequencesQ40258000
Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase geneQ40662320
Gene Therapy With Inducible Nitric Oxide Synthase Protects Against Myocardial Infarction via a Cyclooxygenase-2–Dependent MechanismQ41935847
H(mox-1) constitutes an adaptive response to effect antioxidant cardioprotection: A study with transgenic mice heterozygous for targeted disruption of the Heme oxygenase-1 geneQ43556487
Attenuation of myocardial injury by postconditioning: role of hypoxia inducible factor-1alphaQ43880892
Adenoviral gene transfer to the heart during cardiopulmonary bypass: effect of myocardial protection technique on transgene expressionQ44695348
Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapyQ45428897
Heme oxygenase-1 pathway is involved in delayed protection induced by heat stress against cardiac ischemia-reperfusion injuryQ45712655
AAV vectors and cardiovascular disease: targeting TNF receptor in the heart: clue to way forward with AAV?Q45872009
Heme oxygenase-1 overexpression protects rat hearts from cold ischemia/reperfusion injury via an antiapoptotic pathway.Q45977008
Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrestQ48356691
HO-1 gene overexpression enhances the beneficial effects of superparamagnetic iron oxide labeled bone marrow stromal cells transplantation in swine hearts underwent ischemia/reperfusion: an MRI study.Q51596271
Mild exercise training, cardioprotection and stress genes profile.Q54563988
Echocardiographic assessment of left ventricular mass and systolic function in miceQ72187935
Induction of heme oxygenase-1 can act protectively against cardiac ischemia/reperfusion in vivoQ73300071
Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic miceQ74236314
Cardioprotection: nitric oxide, protein kinases, and mitochondriaQ79780264
HO-1 induction by HIF-1: a new mechanism for delayed cardioprotection?Q80367378
Heme oxygenase-1: the "emerging molecule" has arrivedQ28207978
Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubinQ28235160
Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitisQ28287835
The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase geneQ30454405
The late phase of preconditioningQ33926118
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.Q34168942
Adeno-associated virus: a key to the human genome?Q34459999
Adeno-associated virus vectors can be efficiently produced without helper virusQ34479933
The late phase of preconditioning and its natural clinical application--gene therapyQ34633367
Pharmacological and clinical aspects of heme oxygenaseQ34759206
Ischemic preconditioning. Experimental facts and clinical perspective.Q35021556
Recombinant adeno-associated virus: formulation challenges and strategies for a gene therapy vector.Q35096367
Administration of a CO-releasing molecule at the time of reperfusion reduces infarct size in vivoQ35525303
Triphenyltetrazolium staining of irreversible ischemic injury following coronary artery occlusion in ratsQ35835080
Targeted integration of adeno-associated virus (AAV) into human chromosome 19Q35936149
The innate immune response to adenovirus vectorsQ36026547
Modulation of ventricular function through gene transfer in vivoQ36067860
Cytoprotective effects of heme oxygenase in acute renal failureQ36136514
Heme oxygenase and the cardiovascular-renal systemQ36144605
How many transcription factors does it take to turn on the heme oxygenase-1 gene?Q36600797
Heme oxygenase -1 gene therapy: recent advances and therapeutic applicationsQ36789532
Intracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine modelsQ36806912
Gene therapy with iNOS provides long-term protection against myocardial infarction without adverse functional consequencesQ36829373
Cardioprotection afforded by inducible nitric oxide synthase gene therapy is mediated by cyclooxygenase-2 via a nuclear factor-kappaB dependent pathwayQ36845202
Evidence for an essential role of cyclooxygenase-2 as a mediator of the late phase of ischemic preconditioning in miceQ36952718
Demonstration of an early and a late phase of ischemic preconditioning in miceQ36982103
Gene transfer of inducible nitric oxide synthase affords cardioprotection by upregulating heme oxygenase-1 via a nuclear factor-{kappa}B-dependent pathwayQ37401916
AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS.Q37622300
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectgene therapyQ213901
P304page(s)1367-1377
P577publication date2011-07-22
P1433published inBasic Research in CardiologyQ2453360
P1476titleGene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences
P478volume106

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cites work (P2860)
Q44728568Association of bilirubin with coronary artery calcification and cardiovascular events in the general population without known liver disease: the Heinz Nixdorf Recall study
Q47895659Delayed remote ischemic preconditioning produces an additive cardioprotection to sevoflurane postconditioning through an enhanced heme oxygenase 1 level partly via nuclear factor erythroid 2-related factor 2 nuclear translocation
Q40258000Gene transfer as a strategy to achieve permanent cardioprotection I: rAAV-mediated gene therapy with inducible nitric oxide synthase limits infarct size 1 year later without adverse functional consequences
Q42407527Gene transfer of heme oxygenase-1 using an adeno-associated virus serotype 6 vector prolongs cardiac allograft survival
Q84732981Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of
Q92698553HO-1 overexpression and underexpression: Clinical implications
Q38860810Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival
Q38823562Heme Oxygenases in Cardiovascular Health and Disease
Q38262595Heme oxygenase-1: an emerging therapeutic target to curb cardiac pathology
Q31081214Inhaled carbon monoxide provides cerebral cytoprotection in pigs
Q91433898Modulation of the monocyte/macrophage system in heart failure by targeting heme oxygenase-1
Q40247945Plasma bilirubin values on admission and ventricular remodeling after a first anterior ST-segment elevation acute myocardial infarction.
Q36109838The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning
Q38115527Therapeutic approaches to limit hemolysis-driven endothelial dysfunction: scavenging free heme to preserve vasculature homeostasis
Q37174071Tongguan Capsule Protects against Myocardial Ischemia and Reperfusion Injury in Mice
Q33847244Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome

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