Single N277A substitution in C2 of simian immunodeficiency virus envelope influences vaccine-elicited CD4i neutralizing and anti-V2 antibody responses.

scientific article published on 30 March 2017

Single N277A substitution in C2 of simian immunodeficiency virus envelope influences vaccine-elicited CD4i neutralizing and anti-V2 antibody responses. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2017.03.062
P698PubMed publication ID28366604

P50authorL LiuQ73365179
P2093author name stringHui Wang
Zhiwei Chen
Ling Chen
Caijun Sun
Jia Guo
Lin Cheng
Linqi Zhang
Teng Zuo
Xian Tang
P2860cites workCharacterization and epitope mapping of neutralizing monoclonal antibodies produced by immunization with oligomeric simian immunodeficiency virus envelope proteinQ39592994
Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loopsQ39602333
F18, a novel small-molecule nonnucleoside reverse transcriptase inhibitor, inhibits HIV-1 replication using distinct binding motifs as demonstrated by resistance selection and docking analysis.Q39692280
Epitope mapping of two immunodominant domains of gp41, the transmembrane protein of human immunodeficiency virus type 1, using ten human monoclonal antibodiesQ40106699
Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strainsQ40621073
Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodiesQ40682865
Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodiesQ41621929
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Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccinesQ42230293
Posttranslational modifications within the HIV-1 envelope glycoprotein which restrict virus assembly and CD4-dependent infectionQ44030866
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Impact of glycosylation on antigenicity of simian immunodeficiency virus SIV239: induction of rapid V1/V2-specific non-neutralizing antibody and delayed neutralizing antibody following infection with an attenuated deglycosylated mutantQ45397780
A simplified method for the rapid fluorometric assessment of antibody-dependent cell-mediated cytotoxicity.Q52841139
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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1Q24645530
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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9Q27644478
Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 BindingQ27670829
Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep SequencingQ27671696
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Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeysQ28751926
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Broadly cross-reactive HIV-1-neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexesQ30706865
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B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.Q33373664
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Comprehensive analysis of pathogen-specific antibody response in vivo based on an antigen library displayed on surface of yeastQ33973410
Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain.Q33987417
Simian immunodeficiency virus infection evades vaccine-elicited antibody responses to V2 regionQ35549289
The highly conserved glycan at asparagine 260 of HIV-1 gp120 is indispensable for viral entryQ35604541
Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeysQ35729899
CCR5 antagonist TD-0680 uses a novel mechanism for enhanced potency against HIV-1 entry, cell-mediated infection, and a resistant variantQ35956560
Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeysQ36300153
Antigenic conservation and immunogenicity of the HIV coreceptor binding siteQ36403587
Mucosal priming with a replicating-vaccinia virus-based vaccine elicits protective immunity to simian immunodeficiency virus challenge in rhesus monkeysQ36827361
The principal neutralization determinant of simian immunodeficiency virus differs from that of human immunodeficiency virus type 1Q36839199
Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope proteinQ37207862
Human monoclonal antibodies and engineered antibody domains as HIV-1 entry inhibitorsQ37388409
A three-dimensional model to analyze drug-drug interactionsQ37794779
Primary SIVsm isolates use the CCR5 coreceptor from sooty mangabeys naturally infected in west Africa: a comparison of coreceptor usage of primary SIVsm, HIV-2, and SIVmacQ38942816
CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicityQ39370718
P433issue19
P407language of work or nameEnglishQ1860
P921main subjectSimian immunodeficiency virusQ1890246
P1104number of pages10
P304page(s)2582-2591
P577publication date2017-03-31
P1433published inVaccineQ7907941
P1476titleSingle N277A substitution in C2 of simian immunodeficiency virus envelope influences vaccine-elicited CD4i neutralizing and anti-V2 antibody responses
P478volume35

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