| scholarly article | Q13442814 |
| P50 | author | Martin Christian Michel | Q57055217 |
| P2093 | author name string | Dieter Rosskopf | |
| Karl H Jakobs | |||
| Martina Schmidt | |||
| Paschal A Oude Weernink | |||
| Christof Börgermann | |||
| Christian Rimmbach | |||
| Matthias B Stope | |||
| Maider López De Jesús | |||
| Viktoria N Ananaba | |||
| Yvonne Mahlke | |||
| P2860 | cites work | A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia | Q22004019 |
| Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP | Q22008544 | ||
| A family of cAMP-binding proteins that directly activate Rap1 | Q22008551 | ||
| Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3 | Q22253952 | ||
| Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs | Q22253953 | ||
| The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane | Q24297422 | ||
| Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family | Q24322586 | ||
| Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap | Q24564137 | ||
| An Eph receptor regulates integrin activity through R-Ras | Q24643888 | ||
| The ADP-ribosylation factor (ARF)-related GTPase ARF-related protein binds to the ARF-specific guanine nucleotide exchange factor cytohesin and inhibits the ARF-dependent activation of phospholipase D | Q28139704 | ||
| Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B | Q28205068 | ||
| A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase | Q28206321 | ||
| p63RhoGEF and GEFT are Rho-specific guanine nucleotide exchange factors encoded by the same gene | Q28255191 | ||
| GAP control: regulating the regulators of small GTPases | Q28271241 | ||
| The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras | Q28275924 | ||
| Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis | Q28343294 | ||
| A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A | Q28507307 | ||
| cAMP-GEFII is a direct target of cAMP in regulated exocytosis | Q28512994 | ||
| Crk activation of JNK via C3G and R-Ras | Q28609331 | ||
| A growing family of guanine nucleotide exchange factors is responsible for activation of ras-family GTPases | Q29040265 | ||
| R-Ras controls membrane protrusion and cell migration through the spatial regulation of Rac and Rho | Q33564310 | ||
| The unique N-terminus of R-ras is required for Rac activation and precise regulation of cell migration | Q33768553 | ||
| A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. | Q34156405 | ||
| Retroviral delivery of small interfering RNA into primary cells | Q34380512 | ||
| Integration of calcium and Ras signalling. | Q34623801 | ||
| Ras GTPases: integrins' friends or foes? | Q35564604 | ||
| Linking Rap to cell adhesion | Q36076035 | ||
| The small GTP-binding protein R-Ras can influence integrin activation by antagonizing a Ras/Raf-initiated integrin suppression pathway | Q36879109 | ||
| Heterologous expression and characterization of the human R-ras gene product | Q36919721 | ||
| The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon | Q40304833 | ||
| Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors | Q40524023 | ||
| R-Ras alters Ca2+ homeostasis by increasing the Ca2+ leak across the endoplasmic reticular membrane. | Q40670642 | ||
| Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity | Q40772047 | ||
| CalDAG-GEFIII activation of Ras, R-ras, and Rap1. | Q40876374 | ||
| Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3. | Q40886547 | ||
| Phospholipase D stimulation by receptor tyrosine kinases mediated by protein kinase C and a Ras/Ral signaling cascade. | Q40915861 | ||
| Muscarinic receptor-stimulated cytosol-membrane translocation of RhoA. | Q41126834 | ||
| The Ras-related protein R-ras interacts directly with Raf-1 in a GTP-dependent manner | Q42091003 | ||
| ADP ribosylation of Arg41 of Rap by ExoS inhibits the ability of Rap to interact with its guanine nucleotide exchange factor, C3G. | Q43547714 | ||
| Epac: a new cAMP target and new avenues in cAMP research | Q43859972 | ||
| Integrin activation by R-ras. | Q45995226 | ||
| R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis | Q46803107 | ||
| R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways. | Q53448525 | ||
| p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor. | Q54044454 | ||
| Inhibition of phospholipase C-ε by Gi-coupled receptors | Q56602292 | ||
| Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes | Q59074281 | ||
| P433 | issue | 31 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | G protein-coupled receptor | Q38173 |
| P304 | page(s) | 21837-21847 | |
| P577 | publication date | 2006-06-05 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation | |
| P478 | volume | 281 |
| Q24296340 | A phosphodiesterase 3B-based signaling complex integrates exchange protein activated by cAMP 1 and phosphatidylinositol 3-kinase signals in human arterial endothelial cells |
| Q35621991 | A short splicing isoform of afadin suppresses the cortical axon branching in a dominant-negative manner |
| Q39284158 | Allosteric Modulation of GPCRs: New Insights and Potential Utility for Treatment of Schizophrenia and Other CNS Disorders |
| Q27863934 | Cell physiology of cAMP sensor Epac |
| Q91121458 | Chromaffin Cells of the Adrenal Medulla: Physiology, Pharmacology, and Disease |
| Q36711265 | Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes |
| Q24293510 | Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin |
| Q24657902 | Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity |
| Q36421321 | Epac activation sensitizes rat sensory neurons through activation of Ras. |
| Q38065643 | Epac in cardiac calcium signaling. |
| Q34667012 | Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors |
| Q37051159 | Epac: effectors and biological functions |
| Q48146929 | Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B. |
| Q26829916 | Functional regulation of phospholipase D expression in cancer and inflammation |
| Q34295806 | Inflammatory signals enhance piezo2-mediated mechanosensitive currents |
| Q44056045 | InlB-mediated Listeria monocytogenes internalization requires a balanced phospholipase D activity maintained through phospho-cofilin |
| Q50126142 | Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment. |
| Q36981091 | Ion channel regulation by Ras, Rho, and Rab small GTPases. |
| Q44478653 | Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway. |
| Q48323009 | Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation |
| Q38166604 | Multiple facets of cAMP signalling and physiological impact: cAMP compartmentalization in the lung |
| Q28581578 | Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac |
| Q34399823 | Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders |
| Q37784750 | Orthosteric- and allosteric-induced ligand-directed trafficking at GPCRs |
| Q33624262 | Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair |
| Q37950792 | Phosphodiesterases and subcellular compartmentalized cAMP signaling in the cardiovascular system |
| Q34268347 | Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancer |
| Q36716517 | Phospholipase D signaling: orchestration by PIP2 and small GTPases |
| Q28567162 | Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation |
| Q36403779 | Ras family small GTPase-mediated neuroprotective signaling in stroke |
| Q30491431 | Real-time measurements of cAMP production in live Dictyostelium cells |
| Q34280449 | Regulation of PC12 cell differentiation by cAMP signaling to ERK independent of PKA: do all the connections add up? |
| Q27003242 | Role of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiology |
| Q37109688 | Small GTP-binding proteins and their regulators in cardiac hypertrophy |
| Q42238539 | The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells |
| Q35047496 | The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity |
| Q38934306 | The role of Epac in the heart. |
| Q37632467 | The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function |
| Q35827050 | Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras |
| Q60046831 | What's New in Endocrinology: The Chromaffin Cell |
| Q33866295 | [EXPRESS] Epac and Nociceptor Sensitization |
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