| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1039248703 |
| P356 | DOI | 10.1007/S12035-015-9548-9 |
| P698 | PubMed publication ID | 26607633 |
| P50 | author | Bianca Seminotti | Q80665150 |
| Marília Danyelle Nunes Rodrigues | Q86807699 | ||
| Abel Santamaría | Q88868534 | ||
| Moacir Wajner | Q89163680 | ||
| Guilhian Leipnitz | Q73319960 | ||
| P2093 | author name string | Ana Laura Colín-González | |
| Alexandre Umpierrez Amaral | |||
| Rafael Teixeira Ribeiro | |||
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| Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I | Q36025285 | ||
| Novel crosstalk between ERK MAPK and p38 MAPK leads to homocysteine-NMDA receptor-mediated neuronal cell death | Q36569325 | ||
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| CT and MR of the brain in glutaric acidemia type I: a review of 59 published cases and a report of 5 new patients | Q36687335 | ||
| Neuroinflammation and regulation of glial glutamate uptake in neurological disorders | Q36819684 | ||
| Hormetic dietary phytochemicals | Q37083908 | ||
| Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: a possible mechanism for brain injury in glutaric aciduria type I. | Q48367381 | ||
| Inhibition of brain glutamate decarboxylase by glutarate, glutaconate, and β-Hydroxyglutarate: Explanation of the symptoms in glutaric aciduria? | Q48403320 | ||
| Lysine intake and neurotoxicity in glutaric aciduria type I: towards a rationale for therapy? | Q48461876 | ||
| Time course of oxidative events in the hippocampus following intracerebroventricular infusion of quinolinic acid in mice | Q48501833 | ||
| Induction of oxidative stress in brain of glutaryl-CoA dehydrogenase deficient mice by acute lysine administration | Q48599620 | ||
| Regional development of glutamate dehydrogenase in the rat brain | Q48648481 | ||
| Test-strip method for measuring lactate in whole blood. | Q52521873 | ||
| Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology. | Q53938809 | ||
| 3-Hydroxyglutaric and glutaric acids are neurotoxic through NMDA receptors in vitro. | Q54644825 | ||
| Melatonin reduces oxidative neurotoxicity due to quinolinic acid: | Q59489064 | ||
| Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress | Q67493487 | ||
| The action of acute alcoholic intoxication on the antioxidant system and creatine kinase activity in the brain of rat embryos | Q67836358 | ||
| Differential investigation of the capacity of succinate oxidation in human skeletal muscle | Q70117911 | ||
| Glutathione reductase | Q70123854 | ||
| Glutathione S-transferase (transferase π) from human placenta is identical or closely related to glutathione S-transferase (transferase ϱ) from erythrocytes | Q70968101 | ||
| 44 Glutathione peroxidase | Q71070215 | ||
| Inhibition of creatine kinase by S-nitrosoglutathione | Q71448124 | ||
| Biochemical and molecular investigations in respiratory chain deficiencies | Q72792351 | ||
| Inhibition of synaptosomal [3H]glutamate uptake and [3H]glutamate binding to plasma membranes from brain of young rats by glutaric acid in vitro | Q73450645 | ||
| Semiautomated measurement of nitrate in biological fluids | Q74339100 | ||
| Pathogenesis of CNS involvement in disorders of amino and organic acid metabolism | Q37130117 | ||
| Homocysteine-NMDA receptor-mediated activation of extracellular signal-regulated kinase leads to neuronal cell death | Q37357144 | ||
| Kynurenines with neuroactive and redox properties: relevance to aging and brain diseases. | Q37623378 | ||
| Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms | Q37992617 | ||
| Quinolinic acid: an endogenous neurotoxin with multiple targets | Q38148752 | ||
| Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases | Q38175104 | ||
| Diabetes and the brain: oxidative stress, inflammation, and autophagy | Q38248610 | ||
| Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress | Q38355236 | ||
| Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis | Q38358203 | ||
| The kynurenine pathway and neurodegenerative disease. | Q38378952 | ||
| Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2. | Q40687391 | ||
| p38 MAPK-mediated transcriptional activation of inducible nitric-oxide synthase in glial cells. Roles of nuclear factors, nuclear factor kappa B, cAMP response element-binding protein, CCAAT/enhancer-binding protein-beta, and activating transcriptio | Q40727546 | ||
| Hypothesis: a role for quinolinic acid in the neuropathology of glutaric aciduria type I. | Q41356760 | ||
| Regulation of aortic CuZn-superoxide dismutase with copper. Effects in vivo | Q42100930 | ||
| Energetic dysfunction in quinolinic acid-lesioned rat striatum | Q42445269 | ||
| Glutaric acid stimulates glutamate binding and astrocytic uptake and inhibits vesicular glutamate uptake in forebrain from young rats | Q42466797 | ||
| Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III). | Q42482897 | ||
| Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice | Q42522447 | ||
| Evidence that 3-hydroxyglutaric acid interacts with NMDA receptors in synaptic plasma membranes from cerebral cortex of young rats. | Q42634601 | ||
| Use of guidelines improves the neurological outcome in glutaric aciduria type I. | Q42843854 | ||
| Mouse model of encephalopathy and novel treatment strategies with substrate competition in glutaric aciduria type I. | Q43124751 | ||
| Changes in thiol content and expression of glutathione redox system genes in the hippocampus and cerebellum in Alzheimer's disease | Q43566869 | ||
| Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues | Q43586101 | ||
| Contribution of reactive oxygen species to 3-hydroxyglutarate neurotoxicity in primary neuronal cultures from chick embryo telencephalons | Q43649228 | ||
| Potentiation of 3-hydroxyglutarate neurotoxicity following induction of astrocytic iNOS in neonatal rat hippocampal cultures | Q43650968 | ||
| Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B. | Q43815830 | ||
| Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons | Q43981149 | ||
| Ca(2+) and Na(+) dependence of 3-hydroxyglutarate-induced excitotoxicity in primary neuronal cultures from chick embryo telencephalons | Q44083758 | ||
| 3-Hydroxyglutaric acid induces oxidative stress and decreases the antioxidant defenses in cerebral cortex of young rats | Q44225349 | ||
| Glutaric acid induces oxidative stress in brain of young rats | Q44306271 | ||
| Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles | Q44373729 | ||
| Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum. | Q45258661 | ||
| JAK2 inhibition is neuroprotective and reduces astrogliosis after quinolinic acid striatal lesion in adult mice | Q45772805 | ||
| Kinetic characterization of l-[(3)H]glutamate uptake inhibition and increase oxidative damage induced by glutaric acid in striatal synaptosomes of rats | Q46310001 | ||
| Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis | Q46310683 | ||
| A diet-induced mouse model for glutaric aciduria type I. | Q46919023 | ||
| Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats. | Q46929065 | ||
| Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation. | Q46935800 | ||
| Early modulation of the transcription factor Nrf2 in rodent striatal slices by quinolinic acid, a toxic metabolite of the kynurenine pathway | Q46956458 | ||
| GM1 ganglioside prevents seizures, Na+,K+-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole | Q46975028 | ||
| Mitochondrial creatine kinase is a prime target of peroxynitrite-induced modification and inactivation. | Q47921911 | ||
| Rapid and irreversible inhibition of creatine kinase by peroxynitrite | Q48025871 | ||
| Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism | Q48099180 | ||
| Glutaric aciduria: biochemical and morphologic considerations | Q48295638 | ||
| Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system | Q48297749 | ||
| Induction of oxidative stress by chronic and acute glutaric acid administration to rats | Q48304908 | ||
| Evidence that quinolinic acid severely impairs energy metabolism through activation of NMDA receptors in striatum from developing rats. | Q48306465 | ||
| Nitric oxide synthase inhibition prevents acute quinolinate-induced striatal neurotoxicity | Q48357956 | ||
| P433 | issue | 9 | |
| P921 | main subject | knockout mouse | Q1364740 |
| Glutaric aciduria | Q5572455 | ||
| P304 | page(s) | 6459-6475 | |
| P577 | publication date | 2015-11-25 | |
| P1433 | published in | Molecular Neurobiology | Q15716645 |
| P1476 | title | Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I | |
| P478 | volume | 53 |
| Q88611012 | Evaluation of plasma biomarkers of inflammation in patients with maple syrup urine disease |
| Q90593426 | Evidence that Thiosulfate Inhibits Creatine Kinase Activity in Rat Striatum via Thiol Group Oxidation |
| Q48092571 | Experimental Evidence that In Vivo Intracerebral Administration of L-2-Hydroxyglutaric Acid to Neonatal Rats Provokes Disruption of Redox Status and Histopathological Abnormalities in the Brain |
| Q52092139 | Hypoxanthine Induces Neuroenergetic Impairment and Cell Death in Striatum of Young Adult Wistar Rats. |
| Q47299503 | Induction of Neuroinflammatory Response and Histopathological Alterations Caused by Quinolinic Acid Administration in the Striatum of Glutaryl-CoA Dehydrogenase Deficient Mice. |
| Q48589275 | Inter-relation between brain-derived neurotrophic factor and antioxidant enzymes in bipolar disorder |
| Q93177598 | Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers |
| Q64971283 | Neurological manifestations of organic acidurias. |
| Q48006992 | Quantitative profiling of neurotransmitter abnormalities in brain, cerebrospinal fluid, and serum of experimental diabetic encephalopathy male rat. |
| Q46302938 | Toxic Synergism Between Quinolinic Acid and Glutaric Acid in Neuronal Cells Is Mediated by Oxidative Stress: Insights to a New Toxic Model. |
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