Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions

scientific article published on 10 March 2017

Effects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M116.771634
P932PMC publication ID5409473
P698PubMed publication ID28283574

P2093author name stringSuresh V Ambudkar
Biebele Abel
Suneet Shukla
Eduardo E Chufan
P2860cites workNanodiscs for structural and functional studies of membrane proteinsQ38858495
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Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition stateQ41043571
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Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein.Q43099273
Nucleotide-induced structural changes in P-glycoprotein observed by electron microscopy.Q46416788
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Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with DibromobimaneQ57976930
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Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegansQ27673547
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Distinct conformational spectrum of homologous multidrug ABC transportersQ35152093
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Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.Q35604412
Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.Q35756130
The ATPase activity of the P-glycoprotein drug pump is highly activated when the N-terminal and central regions of the nucleotide-binding domains are linked closely togetherQ36137412
Drug-protein hydrogen bonds govern the inhibition of the ATP hydrolysis of the multidrug transporter P-glycoproteinQ36578713
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pumpQ36932440
Design, synthesis, and biological evaluation of (S)-valine thiazole-derived cyclic and noncyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1).Q37527758
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of PolyspecificityQ37591245
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectmicellesQ421110
P304page(s)7066-7076
P577publication date2017-03-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleEffects of a detergent micelle environment on P-glycoprotein (ABCB1)-ligand interactions
P478volume292

Reverse relations

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