Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target

scientific article published on 19 December 2005

Hirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.FEBSLET.2005.12.015
P698PubMed publication ID16380122
P5875ResearchGate publication ID256707724

P50authorYoung-Joon SurhQ91713697
Ki Won LeeQ110415815
Hyong Joo LeeQ110415817
P2093author name stringSung-Hoon Kim
Jung-Hwan Kim
Min-Won Lee
P2860cites workMetalloproteinases: role in breast carcinogenesis, invasion and metastasisQ24803225
Induction of cyclooxygenase-2 by the activated MEKK1 --> SEK1/MKK4 --> p38 mitogen-activated protein kinase pathwayQ28270455
Interleukin-1beta-induced cyclooxygenase-2 expression requires activation of both c-Jun NH2-terminal kinase and p38 MAPK signal pathways in rat renal mesangial cellsQ28568643
Matrix Metalloproteinase Inhibitors and Cancer--Trials and TribulationsQ29544430
Cancer chemoprevention with dietary phytochemicalsQ29617743
Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agentsQ34482337
Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progressionQ35829631
Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemopreventionQ35864033
Transcription factors and mitogen-activated protein kinases as molecular targets for chemoprevention with anti-inflammatory phytochemicalsQ35998653
Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells.Q40425703
Interleukin-1beta induces cyclo-oxygenase-2 expression in gastric cancer cells by the p38 and p44/42 mitogen-activated protein kinase signaling pathwaysQ40771510
Inhibition of cyclooxygenase-2 expression by diarylheptanoids from the bark of Alnus hirsuta var. sibiricaQ40883477
FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathwayQ44020732
Nonsteroidal antiinflammatory drugs and breast cancerQ44378169
Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-kappaB.Q44933923
Nonsteroidal antiinflammatory drugs and colorectal cancer.Q52882781
Vitamins, phytochemicals, diets, and their implementation in cancer chemopreventionQ57214430
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P1104number of pages8
P304page(s)385-392
P577publication date2005-12-19
P1433published inFEBS LettersQ1388051
P1476titleHirsutenone inhibits phorbol ester-induced upregulation of COX-2 and MMP-9 in cultured human mammary epithelial cells: NF-kappaB as a potential molecular target
P478volume580

Reverse relations

cites work (P2860)
Q37821237Anti-carcinogenic properties of curcumin on colorectal cancer
Q39324007Aromatic-turmerone attenuates invasion and expression of MMP-9 and COX-2 through inhibition of NF-κB activation in TPA-induced breast cancer cells
Q39625477Diarylheptanoid hirsutenone enhances apoptotic effect of TRAIL on epithelial ovarian carcinoma cell lines via activation of death receptor and mitochondrial pathway
Q33462048Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study
Q42829544Hirsutenone Directly Targets PI3K and ERK to Inhibit Adipogenesis in 3T3-L1 Preadipocytes
Q38957372Hirsutenone in Alnus extract inhibits akt activity and suppresses prostate cancer cell proliferation
Q38943759Low fucose containing bacterial polysaccharide facilitate mitochondria-dependent ROS-induced apoptosis of human lung epithelial carcinoma via controlled regulation of MAPKs-mediated Nrf2/Keap1 homeostasis signaling.
Q36616301Multiple molecular targets in cancer chemoprevention by curcumin
Q39682416Oleic acid promotes MMP-9 secretion and invasion in breast cancer cells.
Q34739513Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells
Q40150574Phenolic phytochemicals derived from red pine (Pinus densiflora) inhibit the invasion and migration of SK-Hep-1 human hepatocellular carcinoma cells
Q39739498Piceatannol inhibits phorbol ester-induced NF-kappa B activation and COX-2 expression in cultured human mammary epithelial cells
Q34074561Preparative isolation and purification of antioxidative diarylheptanoid derivatives from Alnus japonica by high-speed counter-current chromatography
Q35488214Tat peptide-admixed elastic liposomal formulation of hirsutenone for the treatment of atopic dermatitis in NC/Nga mice
Q35274707Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression
Q46318554The Genus Alnus, A Comprehensive Outline of Its Chemical Constituents and Biological Activities
Q38177256Therapeutic potential of curcumin in digestive diseases
Q80203138UDN glycoprotein inhibits activator protein-1 and matrix metalloproteinase-9 via blocking of oxygen radicals in HT-29 cells

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