C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L.

scientific article published on December 2005

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NCHEMBIO746
P698PubMed publication ID16370373

P50authorRene E ToesQ42494390
Sylvie FournelQ43231249
Cornelis J. M. MeliefQ21552049
Pascal SchneiderQ40058302
P2093author name stringAlberto Bianco
Olivier Chaloin
Johan Hoebeke
Weimin Sun
Hélène Dumortier
Sébastien Wieckowski
Mohammed Habib
Rienk Offringa
Gilles Guichard
Jean-Christophe Peter
Nathalie Trouche
Bernard Vray
P2860cites workThe role of polar interactions in the molecular recognition of CD40L with its receptor CD40Q42846482
T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactionsQ47982736
Help for cytotoxic-T-cell responses is mediated by CD40 signallingQ47982749
Kinetic analysis of adenovirus fiber binding to its receptor reveals an avidity mechanism for trimeric receptor-ligand interactions.Q51603795
CD40 ligand-induced apoptosis is Fas-independent in human multiple myeloma cells.Q54053672
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacyQ58235013
Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesisQ71704445
CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaBQ74145390
Minimal cross-linking and epitope requirements for CD40-dependent suppression of apoptosis contrast with those for promotion of the cell cycle and homotypic adhesions in human B cellsQ74527755
Analysis of the oligomeric requirement for signaling by CD40 using soluble multimeric forms of its ligand, CD154Q74602347
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primatesQ77890140
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40Q77966184
Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and InhibitorsQ88519588
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activationQ24677534
Ligand-receptor binding revealed by the TNF family member TALL-1Q27641102
2 A crystal structure of an extracellular fragment of human CD40 ligandQ27732546
CD40-CD40 ligandQ28143324
Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand bindingQ28293146
Small molecule cytokine mimeticsQ33547168
Role of CD28/CD80-86 and CD40/CD154 costimulatory interactions in host defense to primary herpes simplex virus infectionQ33835246
Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosisQ33835268
The role of CD40 in peripheral T cell tolerance and immunityQ34067144
Synthetic multivalent ligands in the exploration of cell-surface interactionsQ34096477
The molecular architecture of the TNF superfamilyQ34109796
Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.Q35834680
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicityQ36400613
Small peptides as potent mimetics of the protein hormone erythropoietinQ36802815
Peptide agonist of the thrombopoietin receptor as potent as the natural cytokineQ36864987
Dimerization of cell surface receptors in signal transductionQ40579106
P433issue7
P304page(s)377-382
P577publication date2005-12-01
P1433published inNature Chemical BiologyQ904026
P1476titleC3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L
P478volume1