| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M509526200 |
| P698 | PubMed publication ID | 16230348 |
| P2093 | author name string | Hirofumi Kai | |
| Hiroki Yoshida | |||
| Jian-Dong Li | |||
| Hirofumi Jono | |||
| P2860 | cites work | A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway | Q21735927 |
| TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis | Q24314392 | ||
| Toll-like receptor signalling | Q24570126 | ||
| Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B | Q24630721 | ||
| The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor | Q24672820 | ||
| Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling | Q28141969 | ||
| Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain | Q28142613 | ||
| CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members | Q28201693 | ||
| Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB | Q28201706 | ||
| The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination | Q28201717 | ||
| Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction | Q28203920 | ||
| Themes and variations on ubiquitylation | Q28206411 | ||
| Regulatory functions of ubiquitination in the immune system | Q28213222 | ||
| NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway | Q28269436 | ||
| Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection | Q28587620 | ||
| Negative regulation of toll-like receptor-mediated immune responses | Q29619019 | ||
| Inhibition of p38 MAPK by glucocorticoids via induction of MAPK phosphatase-1 enhances nontypeable Haemophilus influenzae-induced expression of toll-like receptor 2. | Q34152480 | ||
| Exploitation of host epithelial signaling networks by respiratory bacterial pathogens | Q35103723 | ||
| The role of Toll-like receptor 2 in microbial disease and immunity | Q35134715 | ||
| Recognition of microbial infection by Toll-like receptors | Q35192575 | ||
| Synergistic activation of NF-kappaB by nontypeable Haemophilus influenzae and tumor necrosis factor alpha | Q35679713 | ||
| Inferences, questions and possibilities in Toll-like receptor signalling | Q35829752 | ||
| Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cells | Q37114758 | ||
| Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB. | Q39318861 | ||
| Negative regulation of JNK signaling by the tumor suppressor CYLD. | Q40501729 | ||
| Haemophilus influenzae type b-outer membrane protein complex glycoconjugate vaccine induces cytokine production by engaging human toll-like receptor 2 (TLR2) and requires the presence of TLR2 for optimal immunogenicity | Q40592090 | ||
| Transforming Growth Factor-β-Smad Signaling Pathway Negatively Regulates Nontypeable Haemophilus influenzae-induced MUC5AC Mucin Transcription via Mitogen-activated Protein Kinase (MAPK) Phosphatase-1-dependent Inhibition of p38 MAPK | Q40649602 | ||
| Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription | Q40703384 | ||
| Glucocorticoids synergistically enhance nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via a negative cross-talk with p38 MAP kinase. | Q40747952 | ||
| Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation | Q42957126 | ||
| Nontypeable Haemophilus influenzae lipoprotein P6 induces MUC5AC mucin transcription via TLR2-TAK1-dependent p38 MAPK-AP1 and IKKbeta-IkappaBalpha-NF-kappaB signaling pathways | Q46058384 | ||
| Epidermal growth factor receptor acts as a negative regulator for bacterium nontypeable Haemophilus influenzae-induced Toll-like receptor 2 expression via an Src-dependent p38 mitogen-activated protein kinase signaling pathway | Q46770898 | ||
| Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination | Q50119689 | ||
| P433 | issue | 49 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | toll-like receptor | Q408004 |
| P304 | page(s) | 41111-41121 | |
| P577 | publication date | 2005-10-17 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 AND TRAF7. | |
| P478 | volume | 280 |
| Q36076152 | A Structural View of Negative Regulation of the Toll-like Receptor-Mediated Inflammatory Pathway. |
| Q54341048 | A novel mutation of CYLD in a Chinese family with multiple familial trichoepithelioma. |
| Q35011162 | Bacterial LPS up-regulated TLR3 expression is critical for antiviral response in human monocytes: evidence for negative regulation by CYLD |
| Q37322774 | CYLD Promotes TNF-α-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells. |
| Q35412516 | CYLD negatively regulates nontypeable Haemophilus influenzae-induced IL-8 expression via phosphatase MKP-1-dependent inhibition of ERK. |
| Q35916665 | CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt |
| Q39210955 | CYLD, A20 and OTULIN deubiquitinases in NF-κB signaling and cell death: so similar, yet so different |
| Q35565726 | CYLD-mediated signaling and diseases. |
| Q37448141 | CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes |
| Q38239700 | Cell death and deubiquitinases: perspectives in cancer |
| Q42598404 | Cloning, promoter analysis and expression of the tumor necrosis factor receptor-associated factor 6 (TRAF6) in Japanese scallop (Mizuhopecten yessoensis). |
| Q38750090 | Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor. |
| Q36483175 | Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88. |
| Q37945451 | Deubiquitinases in cancer: new functions and therapeutic options. |
| Q98771233 | Deubiquitinating Enzyme: A Potential Secondary Checkpoint of Cancer Immunity |
| Q36229402 | Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses |
| Q42510282 | Deubiquitinating enzyme CYLD regulates the peripheral development and naive phenotype maintenance of B cells |
| Q33836097 | Deubiquitinating enzymes as promising drug targets for infectious diseases |
| Q37184075 | Deubiquitylation and regulation of the immune response |
| Q34613581 | Differential expression of Toll-like receptors in dendritic cells of patients with dengue during early and late acute phases of the disease |
| Q48109121 | Diffuse midline skull base meningiomas: identification of a rare and aggressive subgroup of meningiomas |
| Q38122815 | Emerging roles of E3 ubiquitin ligases in autophagy |
| Q57191736 | Genetic Alterations of TRAF Proteins in Human Cancers |
| Q35023017 | Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M. |
| Q42746137 | IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer |
| Q34730816 | IKBKE phosphorylation and inhibition of FOXO3a: a mechanism of IKBKE oncogenic function |
| Q42773716 | IMPDHII protein inhibits Toll-like receptor 2-mediated activation of NF-kappaB. |
| Q37851354 | IRAK-M regulation and function in host defense and immune homeostasis |
| Q34910947 | Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway |
| Q36637874 | IkappaB kinase complexes: gateways to NF-kappaB activation and transcription |
| Q54110117 | Importance of Validating Antibodies and Small Compound Inhibitors Using Genetic Knockout Studies-T Cell Receptor-Induced CYLD Phosphorylation by IKKε/TBK1 as a Case Study. |
| Q33346667 | Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells |
| Q36815462 | Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD. |
| Q37575463 | Interplay between Inflammation and Stemness in Cancer Cells: The Role of Toll-Like Receptor Signaling. |
| Q91975649 | Keeping Cell Death in Check: Ubiquitylation-Dependent Control of TNFR1 and TLR Signaling |
| Q33676038 | Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells |
| Q40312229 | MicroRNA miR-126-5p Enhances the Inflammatory Responses of Monocytes to Lipopolysaccharide Stimulation by Suppressing Cylindromatosis in Chronic HIV-1 Infection |
| Q26796229 | Molecular basis of hypohidrotic ectodermal dysplasia: an update |
| Q63247114 | Mutated cylindromatosis gene affects the functional state of dendritic cells |
| Q36645845 | Negative regulatory approaches to the attenuation of Toll-like receptor signaling |
| Q34150094 | PKCθ synergizes with TLR-dependent TRAF6 signaling pathway to upregulate MUC5AC mucin via CARMA1. |
| Q24643034 | Pathogen recognition and inflammatory signaling in innate immune defenses |
| Q38097498 | Pathogen recognition receptors: ligands and signaling pathways by Toll-like receptors |
| Q37225102 | Pattern-recognition receptor signaling regulator mRNA expression in humans and mice, and in transient inflammation or progressive fibrosis |
| Q94592174 | Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7 |
| Q28287502 | Protein phosphatase 4 negatively regulates LPS cascade by inhibiting ubiquitination of TRAF6 |
| Q36474924 | Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages |
| Q24645701 | Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes |
| Q41782395 | Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD |
| Q34285271 | Regulation of MyD88 Aggregation and the MyD88-dependent Signaling Pathway by Sequestosome 1 and Histone Deacetylase 6 |
| Q28588773 | Regulation of T cell development by the deubiquitinating enzyme CYLD |
| Q37769479 | Regulation of Toll-like receptor signaling in the innate immunity |
| Q36266490 | STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma |
| Q39992138 | Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate. |
| Q33900624 | Serum response factor controls CYLD expression via MAPK signaling pathway |
| Q38334794 | Signaling mechanisms regulating B-lymphocyte activation and tolerance |
| Q33355817 | Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2 |
| Q37728927 | Synergistic and feedback signaling mechanisms in the regulation of inflammation in respiratory infections |
| Q57801762 | TGF-β signaling pathway mediated by deubiquitinating enzymes |
| Q38840587 | TRAF3 signaling: Competitive binding and evolvability of adaptive viral molecular mimicry. |
| Q42773665 | TRAF7 protein promotes Lys-29-linked polyubiquitination of IkappaB kinase (IKKgamma)/NF-kappaB essential modulator (NEMO) and p65/RelA protein and represses NF-kappaB activation |
| Q37617439 | The Deubiquitinating Enzyme Cylindromatosis Dampens CD8+ T Cell Responses and Is a Critical Factor for Experimental Cerebral Malaria and Blood-Brain Barrier Damage |
| Q39844672 | The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon |
| Q64924690 | The Many Roles of Ubiquitin in NF-κB Signaling. |
| Q40112182 | The bacterium, nontypeable Haemophilus influenzae, enhances host antiviral response by inducing Toll-like receptor 7 expression: evidence for negative regulation of host anti-viral response by CYLD. |
| Q48326227 | The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis |
| Q43416524 | The long noncoding RNA MALAT1 regulates the lipopolysaccharide-induced inflammatory response through its interaction with NF-κB. |
| Q36875508 | The negative regulation of Toll-like receptor and associated pathways |
| Q36739316 | The papain-like protease of porcine epidemic diarrhea virus negatively regulates type I interferon pathway by acting as a viral deubiquitinase |
| Q37959350 | The seventh ring: exploring TRAF7 functions. |
| Q24305326 | The tumor suppressor CYLD regulates entry into mitosis |
| Q33384295 | The ubiquitin system, disease, and drug discovery |
| Q38126062 | Toll-like receptor 3 in viral pathogenesis: friend or foe? |
| Q55047168 | Transcriptional analyses provide new insight into the late-stage immune response of a diseased Caribbean coral. |
| Q37165388 | Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation |
| Q54976742 | Tumor necrosis factor α-induced protein 3 (A20) is dysregulated in pediatric Crohn disease. |
| Q33302126 | Tumor suppressor CYLD acts as a negative regulator for non-typeable Haemophilus influenza-induced inflammation in the middle ear and lung of mice |
| Q40607338 | Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner |
| Q36585593 | Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling |
| Q34503492 | Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets |
| Q28393834 | Uncoupling of Pyrin-only protein 2 (POP2)-mediated dual regulation of NF-κB and the inflammasome |
| Q35625506 | Update of cylindromatosis gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling |
| Q30653282 | Vinpocetine inhibits Streptococcus pneumoniae-induced upregulation of mucin MUC5AC expression via induction of MKP-1 phosphatase in the pathogenesis of otitis media |
| Q30361285 | YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB |
| Q54111924 | sNASP inhibits TLR signaling to regulate immune response in sepsis. |
Search more.