Inhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus

scientific article published on 13 January 2010

Inhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TVJL.2009.11.003
P698PubMed publication ID20074986

P2093author name stringHung J Liu
Ying C Wang
Feng L Lin
Ming H Liao
Wen L Shih
Wen T Ji
P2860cites workPhosphorylation and regulation of Akt/PKB by the rictor-mTOR complexQ24295120
Mechanism of activation of protein kinase B by insulin and IGF-1Q24309528
Activation of the N-Ras-PI3K-Akt-mTOR pathway by hepatitis C virus: control of cell survival and viral replicationQ27470019
Regulation of Hepatitis B Virus Replication by the Phosphatidylinositol 3-Kinase-Akt Signal Transduction PathwayQ27481454
Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR functionQ28254826
Protein synthesis in eukaryotes: the growing biological relevance of cap-independent translation initiationQ28278150
Apoptosis induced by bovine ephemeral fever virusQ28293068
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reactionQ28378871
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathwayQ29620730
Rhabdoviruses and the cellular ubiquitin-proteasome system: a budding interactionQ31016943
Bovine ephemeral fever: a reviewQ33537444
Cytopathogenesis and inhibition of host gene expression by RNA virusesQ34010277
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.Q35909879
The expanding TOR signaling networkQ36076060
Oncogenic PI3K deregulates transcription and translationQ36337966
Akt plays a critical role in replication of nonsegmented negative-stranded RNA virusesQ36424046
The TOR signalling network from yeast to man.Q36463859
DNA-activated protein kinase functions in a newly observed S phase checkpoint that links histone mRNA abundance with DNA replication.Q36639073
PI3K-Akt signaling and viral infectionQ37355200
Preferential translation of vesicular stomatitis virus mRNAs is conferred by transcription from the viral genomeQ39320821
Proteins of bovine ephemeral fever virusQ39569795
Bovine ephemeral fever virus-induced apoptosis requires virus gene expression and activation of Fas and mitochondrial signaling pathwayQ39838978
The PI3K inhibitor LY294002 prevents p53 induction by DNA damage and attenuates chemotherapy-induced apoptosis.Q40413928
The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondriaQ43884355
Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.Q44293983
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cellsQ44714283
Phosphatidylinositol 3-kinase confers resistance to encephalomyocarditis and herpes simplex virus-induced cell death through the activation of distinct downstream effectorsQ45735400
P433issue1
P921main subjectbovine ephemeral feverQ19000493
P304page(s)119-123
P577publication date2010-01-13
P1433published inThe Veterinary JournalQ15752615
P1476titleInhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus
P478volume187

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cites work (P2860)
Q90635238Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway
Q34440491Bovine ephemeral fever virus uses a clathrin-mediated and dynamin 2-dependent endocytosis pathway that requires Rab5 and Rab7 as well as microtubules
Q38920596Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF-κB pathways as well as Cox-2-mediated PGE2 /EP receptor signalling to enhance clathrin-mediated virus endocytosis
Q52624893Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.

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