Inhibition of ovarian cancer metastasis by adeno-associated virus-mediated gene transfer of nm23H1 in an orthotopic implantation model

scientific article published on March 2006

Inhibition of ovarian cancer metastasis by adeno-associated virus-mediated gene transfer of nm23H1 in an orthotopic implantation model is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1018815304
P356DOI10.1038/SJ.CGT.7700899
P698PubMed publication ID16179930
P5875ResearchGate publication ID7584006

P2093author name stringHe Y
Li J
Wang S
Chen G
Lu Y
Wang H
Zhou J
Ma D
Gao Q
Xing H
P2860cites workKAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2Q24318405
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Q24635316
Adhesion proteins in the biology of breast cancer: contribution of CD44.Q33688979
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapyQ35232341
Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenovirusesQ35837026
Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vectorQ35872651
Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell linesQ36114910
Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cellsQ40597125
Model for paraaortic lymph node metastasis produced by orthotopic implantation of ovarian carcinoma cells in athymic nude miceQ40605537
nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylationQ40613187
Suppression of human melanoma metastasis following introduction of chromosome 6 is independent of NME1 (Nm23).Q41113073
Effects of cytokine-mediated modulation of nm23 expression on the invasion and metastatic behavior of B16F10 melanoma cells.Q41379878
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expressionQ42048408
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectorsQ43716886
Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapyQ44313937
Peroral gene therapy of lactose intolerance using an adeno-associated virus vectorQ45753463
A phase I study of recombinant adenovirus vector-mediated intraperitoneal delivery of herpes simplex virus thymidine kinase (HSV-TK) gene and intravenous ganciclovir for previously treated ovarian and extraovarian cancer patientsQ45763897
A phase I trial of in vivo gene therapy with the herpes simplex thymidine kinase/ganciclovir system for the treatment of refractory or recurrent ovarian cancerQ45877962
Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cellsQ48229182
Downregulation of metastasis suppressor genes in malignant pheochromocytoma.Q54694695
Nm23-transfected MDA-mB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A31P nuclear magnetic resonance study in vivo and in vitroQ61703290
Reversal of oncogenesis by the expression of a major histocompatibility complex class I geneQ64380400
Gene therapy for cancerQ67514533
Suppression of invasive properties of colon cancer cells by a metastasis suppressor KAI1 geneQ74392360
A patient-like orthotopic implantation nude mouse model of highly metastatic human ovarian cancerQ77352902
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancerQ81430747
P433issue3
P921main subjectovarian cancerQ172341
cancer metastasisQ120912394
P304page(s)266-272
P577publication date2006-03-01
P1433published inCancer Gene TherapyQ15763088
P1476titleInhibition of ovarian cancer metastasis by adeno-associated virus-mediated gene transfer of nm23H1 in an orthotopic implantation model
P478volume13

Reverse relations

cites work (P2860)
Q38706321Adeno-associated virus (AAV) vectors in cancer gene therapy.
Q37629088Advanced new strategies for metastatic cancer treatment by therapeutic stem cells and oncolytic virotherapy
Q37242266Clinical-translational approaches to the Nm23-H1 metastasis suppressor
Q64376947Degradation of DAXX by adenovirus type 12 E1B-55K circumvents chemoresistance of ovarian cancer to cisplatin
Q58695696Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression
Q38019398Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene
Q30435922Learning therapeutic lessons from metastasis suppressor proteins
Q37696280Malignant ascites enhances migratory and invasive properties of ovarian cancer cells with membrane bound IL-6R in vitro
Q30444715Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application
Q37869335Metastasis-suppressor genes in clinical practice: lost in translation?
Q37150537Nm23H1 mediates tumor invasion in esophageal squamous cell carcinoma by regulation of CLDN1 through the AKT signaling
Q36102835Prognostic Value of NME1 (NM23-H1) in Patients with Digestive System Neoplasms: A Systematic Review and Meta-Analysis
Q54297112Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified.
Q36217061Recombinant adeno-associated viruses (rAAV2) facilitate the intraperitoneal gene delivery to cancer cells
Q39602242Regulation of Nm23-H1 and cell invasiveness by Kaposi's sarcoma-associated herpesvirus
Q38246971Regulation of the metastasis suppressor Nm23-H1 by tumor viruses
Q33805699The Nm23-H1 metastasis suppressor as a translational target
Q36429964The role of metastasis suppressor genes in metastatic dormancy
Q33261170Transcription analysis of TIMP-1 and NM23-H1 genes in glioma cell invasion
Q28295975Tumor-vascular interactions and tumor dormancy
Q43166003nm23H1 expression and its role in the evolution of non-gastrointestinal malignancies

Search more.