A Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting

scientific article

A Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CHEM.201604903
P698PubMed publication ID27935144

P50authorMichael OttQ57008971
Nadja C. BigallQ57394191
P2093author name stringYu Xie
Andreas Kirschning
Asha Balakrishnan
David Candito
Jan Frederick Miethe
Katja Seidel
Liang-Liang Wang
P2860cites workFunctionalisation of magnetic nanoparticles for applications in biomedicineQ56058016
The Stille Reaction, 38 Years LaterQ56482541
A Small-Molecule Drug Conjugate for the Treatment of Carbonic Anhydrase IX Expressing TumorsQ57911941
Ansamitocin, a group of novel maytansinoid antibiotics with antitumour properties from NocardiaQ59080536
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applicationsQ29615464
Mutational biosynthesis--a tool for the generation of structural diversity in the biosynthesis of antibioticsQ33211659
Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineeringQ33301352
Recent developments in the maytansinoid antitumor agentsQ35622324
Design and Application of Magnetic-based Theranostic Nanoparticle SystemsQ36940177
Potent antibody drug conjugates for cancer therapyQ37469585
Merging chemical synthesis and biosynthesis: a new chapter in the total synthesis of natural products and natural product librariesQ37996334
Preparation of thermocleavable conjugates based on ansamitocin and superparamagnetic nanostructured particles by a chemobiosynthetic approachQ38944991
Efficacy of anti-RON antibody Zt/g4-drug maytansinoid conjugation (Anti-RON ADC) as a novel therapeutics for targeted colorectal cancer therapyQ38949778
Magnetically triggered dual functional nanoparticles for resistance-free apoptotic hyperthermiaQ39053731
Combined muta- and semisynthesis: a powerful synthetic hybrid approach to access target specific antitumor agents based on ansamitocin P3.Q39428470
Noninvasive remote-controlled release of drug molecules in vitro using magnetic actuation of mechanized nanoparticles.Q39672199
Tumor delivery and in vivo processing of disulfide-linked and thioether-linked antibody-maytansinoid conjugatesQ39778685
Disulfide-linked antibody-maytansinoid conjugates: optimization of in vivo activity by varying the steric hindrance at carbon atoms adjacent to the disulfide linkage.Q53259778
Applications of magnetic nanoparticles in biomedicineQ56031415
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2265-2270
P577publication date2016-12-09
P1433published inChemistry—A European JournalQ898737
P1476titleA Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting
P478volume23

Reverse relations

Q40183635Synthesis of Magnetic-Nanoparticle/Ansamitocin Conjugates-Inductive Heating Leads to Decreased Cell Proliferation In Vitro and Attenuation Of Tumour Growth In Vivo.cites workP2860

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