| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1031680084 |
| P356 | DOI | 10.1186/1742-2094-8-187 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1186/1742-2094-8-187 |
| P932 | PMC publication ID | 3259120 |
| P698 | PubMed publication ID | 22208359 |
| P5875 | ResearchGate publication ID | 51971878 |
| P2093 | author name string | Hyeon-Sook Suh | |
| Leonid Tarassishin | |||
| Sunhee C Lee | |||
| P2860 | cites work | TLR3 ligation activates an antiviral response in human fetal astrocytes: a role for viperin/cig5 | Q24303885 |
| Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation | Q24523761 | ||
| An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist | Q24606097 | ||
| The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs | Q24627506 | ||
| Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155* | Q24627698 | ||
| MicroRNA-155 is induced during the macrophage inflammatory response | Q24683841 | ||
| Alternative activation of macrophages | Q27860939 | ||
| IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway | Q28190704 | ||
| Triggering the interferon antiviral response through an IKK-related pathway | Q28191761 | ||
| IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes | Q28245089 | ||
| TLR3 and TLR4 are innate antiviral immune receptors in human microglia: role of IRF3 in modulating antiviral and inflammatory response in the CNS. | Q42155544 | ||
| Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. | Q42431545 | ||
| Characterization of primary human fetal dissociated central nervous system cultures with an emphasis on microglia | Q42453595 | ||
| Interferon-beta activates multiple signaling cascades in primary human microglia | Q44030477 | ||
| Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation. | Q46311421 | ||
| Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. | Q48485596 | ||
| Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis. | Q48931506 | ||
| Expression of type II nitric oxide synthase in primary human astrocytes and microglia: role of IL-1beta and IL-1 receptor antagonist | Q71687791 | ||
| Differential induction of chemokines in human microglia by type I and II interferons | Q73372530 | ||
| IFNs are critical regulators of IL-1 receptor antagonist and IL-1 expression in human microglia | Q77123505 | ||
| Sensitization to TLR7 agonist in IFN-beta-preactivated dendritic cells | Q80257339 | ||
| Interleukin-1beta and the autoinflammatory diseases | Q83990604 | ||
| MasterCARD: a priceless link to innate immunity | Q28291111 | ||
| IL-28 and IL-29: newcomers to the interferon family | Q28293519 | ||
| Microglia: active sensor and versatile effector cells in the normal and pathologic brain | Q29547240 | ||
| Microglia: a sensor for pathological events in the CNS | Q29620556 | ||
| An autoinflammatory disease due to homozygous deletion of the IL1RN locus | Q33577198 | ||
| Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages | Q33710188 | ||
| Human neuronal cells possess functional cytoplasmic and TLR-mediated innate immune pathways influenced by phosphatidylinositol-3 kinase signaling. | Q33921332 | ||
| The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. | Q34140181 | ||
| Akt contributes to activation of the TRIF-dependent signaling pathways of TLRs by interacting with TANK-binding kinase 1. | Q34151749 | ||
| Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: a critical role for IRF3 | Q34160637 | ||
| Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling | Q34361655 | ||
| Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes | Q34365709 | ||
| Enhancement and diversification of IFN induction by IRF-7-mediated positive feedback | Q34532725 | ||
| Macrophages and microglia in the nervous system | Q34660547 | ||
| Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response | Q36098825 | ||
| Role of microglia in the central nervous system's immune response | Q36273686 | ||
| Microglial phenotype: is the commitment reversible? | Q36365630 | ||
| Glial toll-like receptor signaling in central nervous system infection and autoimmunity | Q36440629 | ||
| HIV-1 accessory proteins VPR and Vif modulate antiviral response by targeting IRF-3 for degradation | Q36559594 | ||
| Antiviral signaling through pattern recognition receptors | Q36693188 | ||
| Interleukin-1 and inflammatory neurodegeneration | Q36979642 | ||
| Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis. | Q37114231 | ||
| MicroRNAs: new regulators of immune cell development and function | Q37223449 | ||
| TLR4/MyD88/PI3K interactions regulate TLR4 signaling | Q37232951 | ||
| Critical regulation of early Th17 cell differentiation by interleukin-1 signaling | Q37250727 | ||
| Akt/GSK3 signaling in the action of psychotropic drugs | Q37301265 | ||
| Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans | Q37374938 | ||
| Do studies in humans better depict Th17 cells? | Q37506968 | ||
| Toll-like receptors in CNS viral infections | Q37581472 | ||
| Microglia in neurodegenerative disease | Q37710380 | ||
| Regulation of antitumor immune responses by the IL-12 family cytokines, IL-12, IL-23, and IL-27. | Q37795583 | ||
| Novel interferon-beta-induced gene expression in peripheral blood cells. | Q38299064 | ||
| The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture | Q38329706 | ||
| Aberrant expression of interferon regulatory factor 3 in human lung cancer. | Q39700615 | ||
| IRF3 mediates a TLR3/TLR4-specific antiviral gene program | Q40700858 | ||
| Regulation of RANTES chemokine gene expression requires cooperativity between NF-kappa B and IFN-regulatory factor transcription factors | Q40881595 | ||
| Interleukin-1, nitric oxide and reactive astrocytes | Q41198741 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P921 | main subject | inflammation | Q101991 |
| microglia | Q1622829 | ||
| P304 | page(s) | 187 | |
| P577 | publication date | 2011-12-30 | |
| P1433 | published in | Journal of Neuroinflammation | Q15716679 |
| P1476 | title | Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway | |
| P478 | volume | 8 |
| Q24810414 | Aberrant expression of interleukin-1β and inflammasome activation in human malignant gliomas |
| Q30279041 | Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway |
| Q38017580 | Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: relevance to human CNS diseases |
| Q110566803 | COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation |
| Q27303057 | Class I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion injury |
| Q47982879 | Correction to: Neuroimmune Response in Ischemic Preconditioning |
| Q41514646 | Effects of Toll-like receptor 3 on herpes simplex virus type-1-infected mouse neural stem cells |
| Q39766214 | H2S mitigates severe acute pancreatitis through the PI3K/AKT-NF-κB pathway in vivo |
| Q21559659 | HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells |
| Q33582709 | IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury |
| Q55059774 | IRF-3 gene polymorphisms are associated with the susceptibility to and the survival in chronic lymphocytic leukemia and could also serve as an auxiliary index. |
| Q38667448 | IRF6 regulates alternative activation by suppressing PPARγ in male murine macrophages |
| Q90750738 | Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains |
| Q38816350 | Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells |
| Q36715802 | Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators |
| Q39448303 | Interferon regulatory factor 3 alters glioma inflammatory and invasive properties |
| Q59350636 | Interferon regulatory factors 3 and 7 have distinct roles in the pathogenesis of alphavirus encephalomyelitis |
| Q27012493 | Interferon-regulatory factors determine macrophage phenotype polarization |
| Q38192651 | Interferons in the central nervous system: a few instruments play many tunes. |
| Q52646149 | Interleukin-1β Signaling in Dendritic Cells Induces Antiviral Interferon Responses. |
| Q36866426 | KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages |
| Q33586594 | LPS and IL-1 differentially activate mouse and human astrocytes: role of CD14 |
| Q47386444 | Macrophage polarization and meta-inflammation |
| Q42461711 | Mesenchymal stem cells induce the ramification of microglia via the small RhoGTPases Cdc42 and Rac1. |
| Q92408379 | MicroRNA Regulated Macrophage Activation in Obesity |
| Q92702834 | Microglia Mediated Neuroinflammation: Focus on PI3K Modulation |
| Q38360452 | Microglia and neuroprotection |
| Q34649089 | Microglia regulate the number of neural precursor cells in the developing cerebral cortex |
| Q92860088 | Modulation of Type-I Interferon Response by hsa-miR-374b-5p During Japanese Encephalitis Virus Infection in Human Microglial Cells |
| Q39317715 | Modulators of microglial activation and polarization after intracerebral haemorrhage |
| Q50020348 | Morphological and functional changes of microglia cultured under different oxygen concentrations and the analysis of related mechanisms. |
| Q38927962 | Neuroimmune Response in Ischemic Preconditioning. |
| Q52659651 | Paclitaxel treatment and PC1/3 knockdown in macrophages is a promising anti-glioma strategy as revealed by proteomics and cytotoxicity studies. |
| Q54941819 | Paeoniflorin exerts neuroprotective effects by modulating the M1/M2 subset polarization of microglia/macrophages in the hippocampal CA1 region of vascular dementia rats via cannabinoid receptor 2. |
| Q30755643 | Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation |
| Q36476232 | Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia |
| Q38732518 | Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice. |
| Q64098521 | Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures |
| Q35999736 | Protective Effects of Edaravone in Adult Rats with Surgery and Lipopolysaccharide Administration-Induced Cognitive Function Impairment |
| Q89598217 | Regulation of 8-Hydroxydaidzein in IRF3-Mediated Gene Expression in LPS-Stimulated Murine Macrophages |
| Q37744777 | Regulation of microglial activation in stroke |
| Q89605003 | Role of Infiltrating Microglia/Macrophages in Glioma |
| Q37126135 | Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging |
| Q39166204 | Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways. |
| Q58610974 | TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity |
| Q33668659 | Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain |
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